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Research shows how superbug DNA helps predict transmission routes
Infection Control Today
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Researchers at Ohio State University have discovered a new class of treatment against methicillin-resistant Staphylococcus aureus as well as evidence of a growing need to quickly genotype individual strains of the organism most commonly referred to as a "superbug." The two separate studies were funded by the Ohio State Center for Clinical and Translational Science with a goal of increasing the MRSA knowledge-base from both a basic science "bench" perspective, as well as using real-time data from infected communities to determine how MRSA spreads.
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Dealing with infectious samples is risky enough.
Why increase your risk by overlooking transport regulations?
Saf-T-Pak provides the solutions required for 49 CFR compliance:
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Infant DNA tests speed diagnosis of rare diseases
The New York Times
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A new method of quickly analyzing the DNA of newborns, zeroing in on mutations that can cause disease, published in the magazine Science Translational Medicine, is a proof of concept – a demonstration in four babies that it is possible to quickly scan a baby's entire DNA and pinpoint a disease-causing mutation in a couple of days instead of the more typical weeks or months. The study's investigators said the test could be one of the first practical fruits of the revolution in sequencing an individual's entire DNA.
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Japanese scientists: Mouse stem cells used to produce eggs
Los Angeles Times
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Reaching a long-sought milestone, Japanese researchers have demonstrated in mice that eggs and sperm can be grown from stem cells and combined to produce healthy offspring, pointing to new treatments for infertility. If the achievement can be repeated in humans — and experts said they are optimistic that such efforts will ultimately succeed — the technique could make it easier for women in their 30s or 40s to become mothers. It could also help men and women whose reproductive organs have been damaged by cancer treatments or other causes.
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Integrated laboratory models
Advance for Administrators of the Laboratory
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If you're a lab professional visiting a foreign land, you should have no problem finding a common conversation topic. A recent study confirms the challenges you are facing in your lab are likely to be the same in most of the developed world.
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Is mass spectrometry ready to challenge ELISA for medical laboratory testing applications?
Dark Daily
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There is a growing role for mass spectrometry in clinical laboratory testing. However, the pace of adoption will depend on further technology enhancements, in tandem with new clinical applications yet to emerge from research laboratories. One such innovation was announced by researchers at the Department of Energy's Pacific Northwest National Laboratory, who developed a new technique that uses mass spec to identify protein biomarkers associated with cancer and other diseases.
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CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
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As a leader in fully automated immunoassay testing systems, Grifols USA Diagnostic Division’s premier product, the TRITURUS® ELISA System is an open, fully automated, multi-test and multi-batch immunoassay system. Grifols USA is a major distributor of quality IVD ELISA tests for Infectious Disease, Autoimmune Diseases and many other disease states. Grifols’ Diagnostic products take the complexity out of clinical diagnostic testing.
1-800-379-0957. diaginfo@grifols.com
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Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit clevelandcliniclabs.com.
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New England pharmacy linked to deadly meningitis outbreak issues recall
The Associated Press via the Chicago Tribune
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The pharmacy that distributed a steroid linked to an outbreak of fungal meningitis has issued a voluntary recall of all of its products, calling the move a precautionary measure. The New England Compounding Center announced the recall. The company said in a news release that the move was taken out of an abundance of caution because of the risk of contamination.
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Squaring genetic vs clinical findings in familial polyposis
Medscape Medical News
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Familial adenomatous polyposis is caused by mutations in the APC gene and 2 different, or biallelic mutations, in the MUTYH gene. However, not all patients with colorectal polyposis are found to carry mutations on these genes. In addition, it is unclear how the extent of polyp burden or the age at development of the first adenoma corresponds to the likelihood of finding mutations in either of these two genes.
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Might smallpox virus help fight a lethal breast cancer?
HealthDay
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New animal research suggests it may be possible to use a form of smallpox virus to infect and kill the tumor cells of a particularly virulent form of breast cancer. To date, this novel approach to attacking what's known as triple-negative breast cancer has centered exclusively around work with mice. By loading up the live "vaccinia" virus in the smallpox vaccine with a specific type of protein, researchers found they could target and disable these particular cancer cells.
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New technologies and methods push imaging capabilities
Laboratory Equipment
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Imaging used to be simply defined as the representation of an object's external form. That definition no longer holds true as researchers now look for more than just an image. They look for more information within an image, such as fluorescent tags, mechanobiological parameters, internal structures, fabrication while imaging and the characterization of materials as yet undefined.
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Study finds increase in fraud in research journals
The Associated Press via Newser
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Fraud in scientific research, while still rare, is growing at a troubling pace, a new study finds. A review of retractions in medical and biological peer-reviewed journals finds the percentage of studies withdrawn because of fraud or suspected fraud has jumped substantially since the mid-1970s. In 1976, there were fewer than 10 fraud retractions for every 1 million studies published, compared with 96 retractions per million in 2007.
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Breast cancer needle biopsy in 'granular' detail
Medscape Medical News
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There are now even more reasons to use less invasive, more efficient needle biopsy in the diagnosis of breast cancer. In a study of 1,135 breast cancer patients in Vermont, needle biopsy – and the related preoperative diagnosis of cancer — improved surgical outcomes, compared with open biopsy.
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New supercomputer speeds cancer genome analysis to seconds
FierceHealthIT
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The launch of a new genomic supercomputing platform that can speed cancer genome analysis from months to seconds is the result of a collaboration between NantHealth, a health technology company founded by billionaire Patrick Soon-Shiong, and several other well-known companies, including Blue Shield of California, Verizon, Bank of America, AT&T, Intel and Hewlett-Packard. The platform analyzed more than 6,000 cancer genomes from more than 3,000 patients with 19 different cancer types in a total time span of 69 hours — or one patient analysis every 47 seconds. Typically, genomic analysis takes roughly eight to 10 weeks to complete.
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Gen Y physicians — including young pathologists — bring different goals and values to their practice of medicine
Dark Daily
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As they hire young pathologists, pathology groups and clinical laboratories will need to factor in the generational preferences of these Gen Y physicians. Gen Y doctors take a much different approach to the practice of medicine than the Gen X and baby boomer doctors who preceded them. It will be important for clinical laboratories and pathology groups serving Gen Y physicians to understand these important differences.
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