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Reuters
The declining effectiveness of antibiotics may make tens of thousands more U.S. patients vulnerable to potentially fatal infections after surgery or chemotherapy, researchers estimate. Up to half of pathogens causing surgical site infections and more than a quarter of bugs leading to infections after chemotherapy are already resistant to antibiotics commonly used in the U.S., the researchers calculate based on an analysis of previously published studies.
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Food and Drug Administration via Infection Control Today
The Food and Drug Administration has approved Genvoya — a fixed-dose combination tablet containing elvitegravir, cobicistat, emtricitabine and tenofovir alafenamide — as a complete regimen for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older. The Centers for Disease Control and Prevention estimates that 1.2 million persons ages 13 years and older are living with HIV infection, and that more than another 150,000 persons in this age range have HIV but are unaware of their infection.
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The Washington Post
Scientists from the Centers for Disease Control and Prevention have identified a puzzling and unsettling new cancer like condition in a 41-year-old man, who is believed to have become ill through a common stomach bug. The case — the first known transmission of cancer cells from a parasite to a human — involves an HIV patient from Colombia who developed multiple, large tumors in various parts of his body.
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University of Chicago Medical Center via ScienceDaily
Introducing certain bacteria into the digestive tracts of mice with melanoma can help their immune systems attack tumor cells. The gains were comparable to treatment with anti-cancer drugs known as checkpoint inhibitors. The combination of bacteria and anti-PD-L1 nearly abolished tumor outgrowth, report scientists.
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PRODUCT SHOWCASE
DARK Daily
More than 300 of the nation's leading quality improvement practitioners in clinical laboratory operations came together recently to share, learn and master the best approaches to improving the quality of medical laboratory operations in ways that improve performance and productivity even while delivering substantial reductions in cost.
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Medical News Today
Some strains of the malaria parasite can take on another form that allows them to hide in the liver. So, if the main thrust of an anti-malaria campaign is targeting the blood stage of the parasite, then it could be undermined by relapses caused by the parasites in the liver.
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Boston University Medical Center via Medical Xpress
Researchers have identified a new regulatory pathway that may play an important role in basal-like breast cancer, a particularly aggressive form of breast cancer often referred to as "triple negative." This pathway may serve as a target for the development of an effective therapeutic.
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Maine Standards Company, LLC Launches VALIDATE® HbA1c For Easier
Calibration Verification / Linearity Testing. VALIDATE® HbA1c is a liquid,
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ranges. Visit www.mainestandards.com or call 1-800-377-9684 for more information.
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The Hill
The diagnostics community has an opportunity to weigh in on the proposed rule from the Centers for Medicare and Medicaid Services that will implement laboratory payment reform provisions of the Protecting Access to Medicare Act. This rule has the potential to make a significant impact on the delivery of laboratory diagnostics.
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The Rockefeller University via Lab Manager
DNA replication is essential to all life, yet many basic mechanisms in that process remain unknown to scientists. The structure of the replisome — a block of proteins responsible for unwinding the DNA helix and then creating duplicate helices for cell division — is one such mystery.
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It’s like having my own Flow cytometry lab at my finger tips. Finally, a simple way to bring flow cytometry CD4 testing in-house. MORE
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Outbreak News Today
Although gonorrhea susceptibility to the antibiotic cefixime has been improving in recent years, suggesting a halt of a drift towards antibiotic resistance, data for 2014 indicates a worsening of susceptibility, according to a study in the Nov. 3 issue of JAMA. Treatments for gonorrhea have been repeatedly jeopardized by anti-microbial resistance.
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