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The Wistar Institute via ScienceDaily
Scientists have successfully engineered novel DNA-encoded monoclonal antibodies targeting Zaire Ebolavirus that were effective in preclinical models. Study results showed that DMAbs were expressed over a wide window of time and offered complete and long-term protection against lethal virus challenges.
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Medical News Today
New research finds that the cancer cells in a particularly aggressive form of pancreatic cancer rely heavily on a key protein to grow and spread. The findings may soon lead to new treatments and prevention strategies.
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Infectious Disease Advisor
Chronic pain is a frequent comorbidity in people living with HIV, with a 2014 systematic review finding a 54 percent point prevalence. Causes of pain vary from the direct effect of HIV-induced peripheral neuropathy, neuropathic pain secondary to chronic inflammation, opportunistic infection and adverse effects from exposure to antiretroviral therapy.
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Broad Institute of MIT and Harvard via Lab Manager
The human genome has its own proofreaders and editors, and their handiwork is not as haphazard as once thought.
When DNA's double helix is broken after damage from, say, exposure to X-rays, molecular machines perform a kind of genetic "auto-correction" to put the genome back together — but those repairs are often imperfect.
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Outbreak News Today
In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.
The findings, published in Molecular and Cellular Proteomics, are especially important since the microbe, Neisseria gonorrhoeae, is considered a “superbug” because of its resistance to all classes of antibiotics available for treating infections.
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Prepare for leadership in a fast-growing field with the M.S. in Medical Laboratory Science at the University of Vermont, a Public Ivy and top 100 research university where close faculty-student mentorship enables the study of medical laboratory science emphasizing research, teaching, and advanced clinical practice.
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HealthDay News
A majority of Americans believe the health threat posed by antibiotic resistance is real and pressing, a new survey shows.
The survey of more than 1,000 adults found that 65 percent believe antibiotic resistance is a public health problem, and 81 percent are worried that antibiotic resistance will make more infections difficult to treat or even deadly.
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News-Medical.Net
New results from a long-running trial to identify which new drugs or combinations of drugs are most effective in which types of breast cancer, show that two genomic tests are bringing the era of truly personalized medicine ever nearer.
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École Polytechnique Fédérale de Lausanne via Laboratory Equipment
There is no doubt that gut bacteria have become one of the most important focuses of biological and medical research. Over the years, we have learned that the different populations of bacteria that inhabit the gut can often have significant effects on various functions of the body, including the immune system.
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Centers for Disease Control and Prevention via Infection Control Today
New data from the Centers for Disease Control and Prevention show tickborne diseases are again on the rise. In 2017, state and local health departments reported a record number of cases of tickborne disease to CDC.
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Purdue University via Medical Xpress
New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires' disease, findings that could have broad implications for development of medicines to fight disease and infection.
"Our immune system protects us from deadly infections, but successful pathogens have evolved many effective ways to subvert its function," said Zhao-Qing Luo, a Purdue University professor of biological sciences and member of the Purdue Institute for Inflammation, Immunology and Infectious Diseases, who led the research.
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Is regenerative medicine the next big thing in Hematology testing?
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SeraSub® is a synthetic serum for use as a component in preparing standards and controls for in-vitro diagnostic tests. Learn more
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Quanta Magazine
Stem cells, famous for replenishing the body’s stockpile of other cell types throughout life, may have an additional, unforeseen ability to cache memories of past wounds and inflammation. New studies in the skin, gut and airways suggest that stem cells, often in partnership with the immune system, can use these memories to improve the responses of tissues to later injuries and pathogenic assaults.
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