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Outbreak News Today
A novel class of anti-microbials that inhibits the function of a key disease-causing component of bacteria could be effective in fighting methicillin-resistant Staphylococcus aureus, one of the major drug-resistant bacterial pathogens, according to researchers at Georgia State University. Their study showed that small molecule analogs that target the functions of SecA, a central part of the general bacterial secretion system required for viability and virulence, have potent antimicrobial activities, reduce the secretion of toxins and can overcome the effect of efflux pumps, which are responsible for multidrug resistance.
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Whitehead Institute for Biomedical Research via ScienceDaily
A map has been created of the DNA loops that comprise the 3-D structure of the human genome and contribute to gene regulation in human embryonic stem cells. The location of genes and regulatory elements within this chromosomal framework will help scientists better navigate their genomic research, establishing relationships between mutations and disease development.
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Medical News Today
An international collaboration of scientists has revealed the molecular function of a protein essential for replication of H5N1 influenza virus. A subdomain of the viral polymerase undergoes large-scale structural reorganization to enable an essential part of the polymerase to enter the nucleus of the infected cell, where the viral genome is replicated. This study, published in the Journal of the American Chemical Society, illustrates how the flexibility of a protein allows it to adapt its function, facilitating infection of the host.
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American Chemical Society via Lab Manager
In a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich source of disease-fighting polyphenols, can help protect against the development of Alzheimer's disease.
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DARK Daily
Expect the topic of diagnostic mistakes to get more media attention in coming years. That is consistent with the efforts of healthcare policymakers to improve patient safety while making it easier for consumers to access information about the quality and cost when selecting hospitals, physicians and medical laboratories.
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Johns Hopkins University Carey Business School via Infection Control Today
The annual delivery of influenza vaccine to the American public is hardly a straight shot from federal health officials to vaccine manufacturers to physicians to patients. A recurring and vexing part of the process is a supply-chain hitch that can leave patients waiting for flu shots even when the supply of the medicine is abundant.
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Outbreak News Today
Chipotle has found itself in more bad press as another outbreak linked to one of their restaurants is at the center of a norovirus outbreak in Boston.
Earlier, Boston College Student Health reported more than 80 Boston College students have come in to Health Services with gastrointestinal symptoms, including vomiting and diarrhea. All of these students indicated that they had eaten at the Chipotle Mexican Grill restaurant in Cleveland Circle during the past weekend.
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It’s like having my own Flow cytometry lab at my finger tips. Finally, a simple way to bring flow cytometry CD4 testing in-house. MORE
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Colorado State University via Lab Manager
A one-of-a-kind instrument built at Colorado State University lets scientists map cellular composition in three dimensions at the nanoscale, allowing researchers to watch how cells respond to new medications at the most minute level ever observed. The new mass-spectral imaging system is the first of its kind in the world, and its applications are just beginning to surface, said Carmen Menoni, a distinguished professor in the Department of Electrical and Computer Engineering.
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Genetic Engineering & Biotechnology News
Investigators at the University of Oregon have recently uncovered molecular events experienced by stem cells as they age, which could provide new avenues toward the discovery of novel therapies for cancer and neurological disorders. The researchers noticed that these changes arise in Drosophila during the development of the central nervous and at that time a specific protein is expressed, blocking tumor formation.
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