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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Jan. 3, 2013


The association of center performance evaluations and kidney transplant volume in the US
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Report cards evaluating transplant center performance have received significant attention in recent years corresponding with the Centers for Medicare and Medicaid Services issue of the 2007 Conditions of Participation. The primary aim was to evaluate the association of report card evaluations with transplant center volume. Researchers utilized data from the Scientific Registry of Transplant Recipients (SRTR) along with six consecutive program-specific reports from January 2007 to July 2009 for adult kidney transplant centers. Among 203 centers, 46 (23 percent) were low performing with statistically significantly lower than expected 1-year graft or patient survival at least once during the study period. More

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Register now for CEOT
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The first annual Cutting Edge of Transplantation (CEOT) meeting is right around the corner. Register now to take advantage of the buy one registration, get one half off deal. Join the experts from Feb. 14-16 in Scottsdale, Ariz., to discuss controversies and challenges related to B cells and antibodies in transplantation. Learn more about this informative meeting by reading the latest Speaker Spotlight, and then register with your colleagues.

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Antibody Mediated Rejection in Liver Transplantation meeting March 2013 in Dallas
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Antibody mediated rejection is a well known and feared entity in all solid organ transplants – except the liver. Previous studies and literature regarding liver allografts have been inconsistent, and mounting evidence has shown the pathologic potential of DSA in liver and SLKT recipients. The goal of this conference is to bring about a meeting of the minds to define AMR in liver transplantation and forge a path for future research in this burgeoning area of research. Program information is available at To register visit


Study: Most living donors would do it again
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A German study found that living kidney donation is safe and most donors report that they would donate again. Still, a small percentage of living kidney donors may experience physical or mental discomforts following donation. Researchers studied 128 living kidney donors and found that less than 10 percent of them reported impaired quality of life directly related to kidney donation. More

The relationship of socio-demographic factors and satisfaction with social support at 5, 10 years after heart transplantation
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Despite the fact that social support has been found to be important to cardiovascular health, there is a paucity of information regarding the relationship between social support and outcomes long term after heart transplantation (HT). The purposes of a recent study were to examine demographic and psychosocial characteristics and their relationship to social support after HT and to identify whether socio-demographic variables are predictors of satisfaction with social support post-HT. More

Transplanted genetically-modified adipose cells offer potential therapy for liver diseases
Medpage Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their injection into the spleen of mice modeling liver disease, to their characterization as "hepatic precursors," and to their subsequent migration through the spleen before engrafting at regenerating sites in the liver by bioluminescent imaging. More

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Declining liver utilization for transplantation in the United States and the impact of donation after cardiac death
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Worsening donor liver quality resulting in decreased organ utilization may be contributing to the recent decline in liver transplants nationally. Researchers conducted a study to examine trends in donor liver utilization and the relationship between donor characteristics and nonuse. The United Network for Organ Sharing database was used to to review all deceased adult organ donors in the United States from whom at least one solid organ was transplanted into a recipient. More

Study: Iron oxide nanoparticles effective for labeling human endothelial cells
Medical News Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team of researchers from three medical institutions in Guangzhou, China, have found that iron oxide nanoparticles (INOPS) are a useful contrast agent for in vivo magnetic resonance tracking of transplanted human endothelial cells. However, the impact of INOPS on the cells varies with a number of factors including the INOPS load. They found that the percentage of iron-labeled cells was significantly lower after 48 hours post-transplantation than at 24 hours post-transplantation. They also found that high INOPS concentration can affect cell activity. High INOPS concentration can induce cell death (apoptosis). More

Low-dose valacyclovir effective for cytomegalovirus prophylaxis
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Low-dose valacyclovir prophylaxis reduces the incidence of cytomegalovirus (CMV) disease in CMV-negative renal transplant recipients who receive a renal allograft from a CMV-infected donor, new findings suggest. It also results in high patient and graft survival rates. More

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Simulation of changes in myocardial tissue properties during left ventricular assistance with a rotary blood pump
Artificial Organs    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers considered a mathematical model to investigate changes in geometric and hemodynamic indices of left ventricular function in response to changes in myofiber contractility and myocardial tissue stiffness during rotary blood pump support. The simulations showed that indices of ventricular geometry, left ventricular shortening fraction, and ejection fraction had the same response to variations in myofiber contractility and myocardial tissue stiffness. Hemodynamic measures showed an inverse relation compared with geometric measures. More

Efficacy of the retreatment of hepatitis C virus infections after liver transplantation: Role of an aggressive approach
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A sustained virological response (SVR) is achieved by 30 percent of naive liver transplantation (LT) recipients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV). Almost no data are available about retreatment. The aim of this study was to assess the efficacy, tolerability and SVR predictors of retreatment. More

Rhinovirus and other respiratory viruses exert different effects on lung allograft function that are not mediated through acute rejection
Clinical Transplantation    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Community acquired respiratory virus (CARV) infections in lung transplant recipients (LTR) have been associated with adverse outcomes, including acute rejection (AR) and decline in allograft function, in some but not in all studies. In a recent study, Spirometry and transbronchial biopsy results of LTR diagnosed with CARV infection over a two-year period were extracted from clinical records. More

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