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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Jan. 31, 2013


Iraq vet undergoes successful double-arm transplant
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A U.S. Army infantryman who lost all four limbs in a 2009 roadside explosion in Iraq has undergone radical transplant surgery that may help him regain use of his arms. In December, the 26-year-old infantryman had successful surgery — a rare double arm transplant — at Johns Hopkins Hospital in Baltimore. More


Live webinars Feb. 13 and 20 — free to AST members
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"Understanding Your Scientific Registry for Transplant Recipients (SRTR) Data" is part of the Business of Transplantation webinar series and airs at 2 p.m. EST on Wednesday, Feb. 13. Register ahead of time at "New Strategies in Hepatitis Management after Solid Organ Transplantation" is part of the Timely Topics in Transplantation webinar series, and registration will open soon at Visit either website for details on webinars in March and beyond!

Membership dues reminder
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If you have not yet remitted payment for your 2013 membership dues, please do so immediately to ensure that you continue to receive all of the benefits of membership with the AST, including discounted meeting registration. Your dues must be paid no later than April 1, 2013 in order to be eligible for member-discounted registration rates to the American Transplant Congress in Seattle. Renewing your membership is easy. Simply log in to the AST website and click on "Renew My Membership" to pay your dues online. A confirmation email will be sent to you once your payment is processed.

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Pay it forward: Invite your colleagues to join AST
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Take part in AST's member-get-a-member program for your chance to win prizes. Talk to your fellow transplantation team members about the AST benefits you find most valuable, and encourage them to join. You'll strengthen the community and help them grow personally and professionally. For each new member you recruit, you will be entered to win an iPad or AST bucks. You will also receive recognition at ATC, on the AST website, and in AST eNews. For more details and guidelines, click here.

CEOT: View the full program
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There is still time to register for the first annual Cutting Edge of Transplantation (CEOT) meeting this Feb. 14-16 in Scottsdale, Ariz. The full program is available online, including rapid-fire abstract presentations and speed roundtable discussions with subject-matter experts.


COP Executive Committee call for nominations
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Nominations are now being taken for executive committee open positions in 10 Communities of Practice (COPs). The deadline to submit nominations is Feb. 22. To nominate yourself or a fellow colleague, you (the nominator) and the nominee must both be a member of that specific COP. Nominees must be an AST member in good standing. If you need to verify your or the nominee's COP membership, please feel free to contact Jason Polinsky at with your membership verification request. To submit a nomination, simply follow the links to forms for the co-chair positions and committee member-at-large positions.

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Blockade of p-selectin sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro, in vivo
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Donor-specific HLA antibodies significantly lower allograft survival, but as yet there are no satisfactory therapies for prevention of antibody-mediated rejection. Intracapillary macrophage infiltration is a hallmark of antibody-mediated rejection, and macrophages are important in both acute and chronic rejection. The purpose of a recent study was to investigate the Fc-independent effect of HLA I antibodies on endothelial cell activation, leading to monocyte recruitment. More

Pre-liver transplant antiviral therapy reduced risk for HCV recurrence
Healio    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Patients with chronic hepatitis C who underwent antiviral treatment before liver transplant were less likely to experience recurrence following transplantation in a recent study. More

Lungs from heavy smokers may be effective for double-lung transplant
Fox News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study found that lungs from selectively chosen donors who have had an extensive smoking history, performed just as well in adult, double-lung transplants as lungs from non-smokers. According to Dr. Sharven Taghavi, a surgical specialist at Temple and one of the study's lead authors, the decision to look at smokers was a result of the desperate need for other avenues for organ recipients. More

High genetic barrier nucleos(t)ide analogue(s) for prophylaxis from hepatitis b virus recurrence after liver transplantation
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The combination of hepatitis B immunoglobulin (HBIG) and nucleos(t)ide analogues [NA(s)] is considered as the standard of care for prophylaxis against HBV recurrence after liver transplantation (LT), but the optimal protocol is controversial. We evaluated the efficacy of the newer NAs with high genetic barrier (hgbNA) [i.e. entecavir (ETV) or tenofovir (TDF)] with or without HBIG as prophylaxis against HBV recurrence after LT. More

Interleukin-28B polymorphism in hepatitis C and liver transplantation
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The discovery of interleukin-28B (IL-28B) single-nucleotide polymorphisms has opened an important new area of research in liver transplantation (LT) for hepatitis C virus (HCV). Both recipient- and donor-derived IL-28B genotypes affect the post-LT treatment response, with sustained virological response (SVR) rates oscillating from >50 percent in homozygotes for the favorable allele (up to 90 percent when this is present in both the recipient and the donor) to less than 15 percent in homozygotes for the unfavorable allele and from 30 percent to more than 50 percent in heterozygotes. More

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Portable heart lets transplant patients go home
MedPage Today (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Patients who received a portable artificial heart were able to return home to await a successful human heart transplant, researchers said. Out of 13 patients who were at imminent risk of death from biventricular failure, and who received a portable pneumatic pulsatile Total Artificial Heart, 12 successfully made it to transplantation, reported Dr. Vigneshwar Kasirajan from the Virginia Commonwealth University Pauley Heart Center in Richmond, Va., and colleagues at the Society of Thoracic Surgeons annual meeting. More

Tumor biology and pre-transplant locoregional treatments determine outcomes in patients with T3 hepatocellular carcinoma undergoing liver transplantation
Clinical Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Liver transplantation is the optimal treatment for patients with hepatocellular carcinoma (HCC) and cirrhosis. This study was conducted to determine the impact of pre-transplant locoregional therapy (LRT) on HCC and researchers' experience with expansion to United Network of Organ Sharing Region 4 T3 (R4T3) criteria. More

Transumbilical portal venous catheterization: A useful adjunct in left lobe living donor liver transplantation
Clinical Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
To improve the processes used for perfusion of the explanted graft and measuring the portal venous pressure in adult living donor transplantation, researchers performed transumbilical portal venous catheterization to reopen the umbilical vein and insert the catheter for seven adult patients undergoing left lobe LDLT. More

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