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AST Cutting Edge of Transplantation happening next week
AST
Register today to secure your spot at this intimate meeting that focuses on long-term graft survival. CEOT features a truly cutting edge experience: a unique program and a truly interactive experience. More than 30 talks tackle the problem of long-term graft survival through new technology, targets and therapeutics.

Beyond meeting hours, there's a multitude of both on-site activities and things to do in the local area. Take a hike along the hotel's walking trail consider a kayaking or hiking adventure with our Arizona Outback Adventures partner. Get some retail therapy at the nearby outlets or just relax by the pool.

This activity is jointly sponsored by Global Education Group and the American Society of Transplantation. Continuing education credit will be offered for physicians, nurses, pharmacists, and transplant coordinators. For full credit details check here. For information about accreditation of this program, please contact Global at 303-395-1782 or inquire@globaleducationgroup.com.

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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


Participate in the AST Institutional Support Program
AST
The AST offers numerous programs for transplant professionals and the support of the community is critically important to the success of the society's programs. By participating in the Institutional Support Program, your center's tax-deductible contribution of $3,000 will increase exposure for your center through electronic marketing, literature, and signage displays, as well as these other valuable benefits. In addition, your institution will be seen throughout the transplant community as having a vested interest in advancing the field of transplantation and improving patient care. Click here to participate in AST's Institutional Support Program, or contact Liz Piegzik, AST Associate Meeting Manager at lpiegzik@myAST.org.

AST thanks the following organizations for their participation in the 2014 Institutional Support Program:
    University of Michigan Transplant Center
    Children's Hospital of Pittsburgh of UPMC

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Become an AST Corporate Affiliate
AST
The AST Corporate Affiliates Program provides an exciting opportunity for companies to support the work of the AST and receive tangible benefits throughout the year.

Benefits of participation include increased visibility, enhanced engagement opportunities, access to new marketing tools, and up-to-date communication about the latest research and advocacy efforts in the field of transplantation. In addition to these benefits, companies participating in this program are invited to meet annually with senior AST leadership to engage in strategic discussions about key issues impacting the field of transplantation.

Click here for additional information, or contact Liz Piegzik, Associate Meeting Manager, at lpiegzik@myAST.org.

AST thanks the following companies for their participation in the 2014 Corporate Affiliates Program:
    Genentech, A Member of the Roche Group
    Novartis Pharmaceuticals
    Roche Diagnostics Corporation
    Veloxis Pharmaceuticals

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New kidney policy webinar on demand and live webinars in February
AST
View AST's webinar on the new OPTN/UNOS kidney allocation policy when it's convenient for you at www.myAST.org/T3.

Register now for these upcoming webinars: Feb. 18 at 2 p.m. EST: Complying with New UNOS Living Donor Care Policies (free to AST members, $25 for non-members) Feb. 21 at 4 p.m. EST: Pathology Webinar for Fellows (free to everyone)

Check out www.myAST.org/education for all upcoming and on demand webinars!

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TRANSPLANT NEWS


Utility of gene expression profiling score variability to predict clinical events in heart transplant recipients
Transplantation (login required)
Gene expression profiling test scores have primarily been used to identify heart transplant recipients who have a low probability of rejection at the time of surveillance testing. It has been hypothesized that the variability of gene expression profiling test scores within a patient may predict risk of future events of allograft dysfunction or death.
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Usefulness of pulmonary capillary wedge pressure as a correlate of left ventricular filling pressures in pulmonary arterial hypertension
The Journal of Heart and Lung Transplantation (login required)
Pulmonary arterial hypertension (PAH) is characterized by a pulmonary capillary wedge pressure (PCWP) of ≤15 mm Hg, given a normal left ventricular filling pressure (LVFP). However, recent studies have shown that, in PAH patients, diagnosis based on PCWP can erroneously classify a significant number of patients compared with diagnosis based on left ventricular end-diastolic pressure (LVEDP). Therefore, we sought to compare the diagnostic accuracy of end-expiratory PCWP and LVEDP measurements in patients suspected of having pulmonary hypertension (PH).
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Featured Advertisers




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The University Of Utah Department Of Surgery is seeking applications for a faculty member to join the multi-organ transplant team at the assistant professor level. This is an opportunity to join an expanding program and a cohesive group of transplant surgeons focused on excellence. The candidate should be board certified in general surgery and have completed an ASTS approved transplantation surgery fellowship. Apply here
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Myocardial regeneration of the failing heart
Heart Failure Reviews (login required)
Human heart failure (HF) is one of the leading causes of morbidity and mortality worldwide. Currently, heart transplantation and implantation of mechanical devices represent the only available treatments for advanced HF. Two alternative strategies have emerged to treat patients with HF. One approach relies on transplantation of exogenous stem cells (SCs) of non-cardiac or cardiac origin to induce cardiac regeneration and improve ventricular function.
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A new classification system for chronic lung allograft dysfunction
The Journal of Heart and Lung Transplantation (login required)
Although survival after lung transplantation has improved significantly during the last decade, chronic rejection is thought to be the major cause of late mortality. The physiologic hallmark of chronic rejection has been a persistent fall in forced expiratory volume in 1 second associated with an obstructive ventilatory defect, for which the term bronchiolitis obliterans syndrome (BOS) was defined to allow a uniformity of description and grading of severity throughout the world.
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Study: Prerecovery liver biopsy in the brain-dead donor
Liver Transplantation (login required)
Prerecovery liver biopsy can potentially to decrease futile recovery and increase utilization of marginal brain-dead donor livers. A case-control study was conducted to examine the logistics, safety, histological precision and liver utilization associated with PLB in BDDs. Twenty-three cases between January 2008 and January 2013 were compared to two groups: 48 sequential and 69 clinically matched controls.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Crossmatch-positive liver transplantation in patients receiving thymoglobulin-rituximab induction (Transplantation)
Liver transplantation versus liver resection in the treatment of hepatocellular carcinoma: A meta-analysis of observational studies (Transplantation)
The extent and predictors of waiting time geographic disparity in kidney transplantation in the US (Transplantation)
Sarcopenia is a prognostic factor in living donor liver transplantation (Liver Transplantation)

Don't be left behind. Click here to see what else you missed.


Impact of IgM and IgG3 Anti-HLA alloantibodies in primary renal allograft recipients
Transplantation (login required)
With standard IgG donor-specific anti-HLA antibody (DSA) testing, it is unclear which immunoglobulin-G (IgG) DSA positive patients will fail. Authors looked further into the immune response by studying immunoglobulin-M (IgM) and IgG subclass 3 (IgG3) DSA to determine if these identify the IgG DSA patients at highest risk for allograft loss.
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Donor hemodynamic profile presages graft survival in donation after cardiac death liver transplantation
Liver Transplantation (login required)
Obligatory exposure to a period of warm ischemia is the defining feature of liver allografts from donation after cardiac death (DCD) donors. Authors explored novel methods for characterizing the dynamic aspects of donor warm ischemia that might be useful in assessing organ quality. The hemodynamic profile during donor warm ischemia was retrospectively studied for 110 Maastricht category III DCD donors.
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