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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Feb. 14, 2013


Registry analysis: Inferior early posttransplant outcomes for recipients of right versus left deceased donor kidneys
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Anatomical differences between right and left kidneys could influence transplant outcome. Receipt of a right kidney is a risk factor for inferior outcomes in the first year after transplantation. A higher incidence of surgical complications suggests the shorter right renal vein may be contributory. The higher susceptibility of right kidneys to injury should be considered in organ allocation. More


Live webinars Feb. 20, March 6 — free to AST members
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Two new webinars in the Timely Topics in Transplantation Webinar Series are now open for registration. "New Strategies in Hepatitis Management after Solid Organ Transplantation" airs on Wednesday, Feb. 20 at 2 p.m. EST. "Meeting the Challenges of Resistance" airs on Wednesday, March 6 at 1 p.m. EST. Visit to register. The fee for non-members is only $25 per webinar.

Invite your colleagues to join AST
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Strengthen the transplant community and get the opportunity to win an iPad or AST bucks when you invite your colleagues to join AST. Pay it forward and tell a colleague why you're a member. You'll help them grow personally and professionally, and you'll be recognized for your referral at ATC, on the AST website, and in AST eNews. For details and guidelines, click here.

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Membership dues reminder
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If you have not yet remitted payment for your 2013 membership dues, please do so immediately to ensure that you continue to receive all of the benefits of membership with the AST, including discounted meeting registration. Your dues must be paid no later than April 1 in order to be eligible for member discounted registration rates to the American Transplant Congress in Seattle. Renewing your membership is easy. Simply log in to the AST website and click on "Renew My Membership" to pay your dues online. A confirmation email will be sent to you once your payment is processed.


COP Executive Committee call for nominations reminder
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Nominations are now being taken for executive committee open positions in 10 Communities of Practice (COPs). The deadline to submit nominations is Feb. 22. To nominate yourself or a fellow colleague, you (the nominator) and the nominee must both be a member of that specific COP. Nominees must be an AST member in good standing. If you need to verify your or the nominee's COP membership, please feel free to contact Jason Polinsky at with your membership verification request. To submit a nomination, simply follow the links to forms for the co-chair positions and committee member-at-large positions.

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Low-dose steroids associated with milder histological changes after pediatric liver transplantation
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Controversy remains about the role of protocol liver biopsy for symptom-free recipients and about the long-term use of low-dose steroids after pediatric liver transplantation (LT). A recent national cross-sectional study examined pediatric recipients who underwent LT between 1987 and 2007. Researchers concluded continuing low-dose steroids indefinitely after pediatric LT may have a positive effect on the long-term histological state of the liver graft. More

Radiation exposure high prior to kidney transplantation
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A study found kidney transplant recipients are exposed to large amounts of ionizing radiation from medical imaging as part of their pre-transplant evaluation. Dr. Anup M. Patel and colleagues at Saint Barnabas Medical Center in Livingston, N.J., reviewed the medical records of 172 kidney transplant recipients who underwent 905 medical imaging procedures involving ionizing radiation. Of these, 28 were exposed to high dose (more than 50 and up to 100 mSv) and 23 were exposed to very high dose (more than 100 mSv) cumulative effective radiation. .

Related article:
Ionizing radiation exposure among kidney transplant recipients due to medical imaging during the pretransplant evaluation (Clinical Journal of the American Society of Nephrology)

Outcome of pediatric heart transplantation recipients treated with ventricular assist device
Pediatric Transplantation    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A recent study was conducted to evaluate the long-term prognosis of pediatric HTx patients treated with VAD before transplantation. The clinical data of six patients bridged to HTx with Berlin Heart EXCOR pediatric device were analyzed retrospectively. It is suggested that the prognosis of pediatric HTx patients treated with VAD before transplantation is not inferior to that of other HTx patients. More

Post-chemo woman pregnant after ovary tissue transplant
The Conversation    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For the first time ever in Australia, a woman whose chemotherapy rendered her infertile has become pregnant using ovarian tissue taken from her body before her cancer treatment, a new study reports. Chemotherapy commonly kills the eggs in a woman's ovaries but the radical new technique, which has only been successful in 20 cases world wide, offers new hope to women who hope to conceive after cancer treatment.

Related article:
First Australian pregnancy after ovarian tissue cryopreservation and subsequent autotransplantation (Medical Journal of Australia)

Significance of and risk factors for the development of central airway stenosis after lung transplantation
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Central airways stenosis (CAS) after lung transplant is a poorly understood complication. Objectives of a recent study were to determine if CAS was associated with chronic rejection or worse survival after transplant as well as to identify factors associated with CAS in a large cohort of lung transplant recipients. More

Association between plasma cyclic guanosine monophosphate levels and hemodynamic instability during liver transplantation
Liver Transplantation    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The activation of cyclic guanosine monophosphate (cGMP) production in patients with end-stage liver disease (ESLD) has been associated with hemodynamic instability during orthotopic liver transplantation (OLT). The aim of this prospective, observational study was to investigate the involvement of cGMP in the mediation of profound hypotension during liver graft reperfusion. More

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Hormonal imbalance in relation to exercise intolerance and ventilatory inefficiency in chronic heart failure
The Journal of Heart and Lung Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Skeletal muscle wasting is associated with altered catabolic/anabolic balance and poor prognosis in patients with chronic heart failure (CHF). A study recently evaluated catabolic and anabolic abnormalities in relation to disease severity in CHF patients. Researchers concluded enhanced catabolic status is significantly associated with exercise intolerance, ventilatory inefficiency and chronotropic incompetence in CHF patients, suggesting a significant contributing mechanism to their limited functional status. More

Characterization and quantification of porcine circulating endothelial cells
Xenotransplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Endothelial damage is a critical step in the development of (xeno) transplantation-related and cardiovascular pathology. In humans, the amount of circulating endothelial cells (CEC) correlates to disease intensity and functions as a valuable damage marker. While (xeno) transplantation and cardiovascular research is regularly performed in porcine models, the paucity of antibodies against porcine endothelium epitopes hinders the use of CEC as damage marker. A recent study aimed to develop a method for porcine CEC detection using anti-human antibodies against porcine endothelium epitopes. More

Donor risk factors, retrieval technique, preservation and ischemia/reperfusion injury in pancreas transplantation
Current Opinion in Organ Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pancreas transplantation is still hampered by a high incidence of early graft loss, and organ quality concerns result in high nonrecovery/discard rates. Demographic donor characteristics, surgical retrieval strategy, preservation fluid and ischemia time are crucial factors in the process of organ selection and are discussed in this review. More

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