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Registry analysis: Inferior early posttransplant outcomes for recipients of right versus left deceased donor kidneys
American Journal of Transplantation (subscription required)
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Anatomical differences between right and left kidneys could influence transplant outcome. Receipt of a right kidney is a risk factor for inferior outcomes in the first year after transplantation. A higher incidence of surgical complications suggests the shorter right renal vein may be contributory. The higher susceptibility of right kidneys to injury should be considered in organ allocation.
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Live webinars Feb. 20, March 6 — free to AST members
AST
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Two new webinars in the Timely Topics in Transplantation Webinar Series are now open for registration. "New Strategies in Hepatitis Management after Solid Organ Transplantation" airs on Wednesday, Feb. 20 at 2 p.m. EST. "Meeting the Challenges of Resistance" airs on Wednesday, March 6 at 1 p.m. EST. Visit www.a-s-t.org/t3 to register. The fee for non-members is only $25 per webinar.
Invite your colleagues to join AST
AST
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Strengthen the transplant community and get the opportunity to win an iPad or AST bucks when you invite your colleagues to join AST. Pay it forward and tell a colleague why you're a member. You'll help them grow personally and professionally, and you'll be recognized for your referral at ATC, on the AST website, and in AST eNews. For details and guidelines, click here.
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Identify Antibodies That May Compromise Graft Survival
- Detect Presence of Complement Fixing Antibodies
- Investigate risk of developing Antibody Mediated Rejection (AMR)
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For Research Use Only. Not for use in diagnostic procedures.
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Membership dues reminder
AST
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If you have not yet remitted payment for your 2013 membership dues, please do so immediately to ensure that you continue to receive all of the benefits of membership with the AST, including discounted meeting registration. Your dues must be paid no later than April 1 in order to be eligible for member discounted registration rates to the American Transplant Congress in Seattle. Renewing your membership is easy. Simply log in to the AST website and click on "Renew My Membership" to pay your dues online. A confirmation email will be sent to you once your payment is processed.
COP Executive Committee call for nominations reminder
AST
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Nominations are now being taken for executive committee open positions in 10 Communities of Practice (COPs). The deadline to submit nominations is Feb. 22. To nominate yourself or a fellow colleague, you (the nominator) and the nominee must both be a member of that specific COP. Nominees must be an AST member in good standing. If you need to verify your or the nominee's COP membership, please feel free to contact Jason Polinsky at jpolinsky@ahint.com with your membership verification request. To submit a nomination, simply follow the links to forms for the co-chair positions and committee member-at-large positions.
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PRODUCT SHOWCASES
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Genetic testing can be a cost-effective way to increase the number of living related donor transplants. Mutational analysis may help direct long-term treatment plans, including pre-operative screening of potential kidney transplant recipients and living related donors.
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✓ Hypothermic preservation of a single kidney using physiologic pulsatile preservation and membrane oxygenation: a proven technology from Waters Medical Systems (more than 40 years clinical experience)
✓ Simplifies the perfusion process (provides more options to view, chart, and trend data, offers web-based remote monitoring, and a transportable design)
✓ Meets or exceeds current FDA standards and AOPO and UNOS Preservation Guidelines.
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When it comes to saving lives, MNX understands organ transplant logistics. Every shipment is urgent, and every step critical. That’s why MNX offers specialty services that are tailored for organ transportation. From expedited ground service to charter flights, MNX has the proven experience and operational resources you can count on.
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FEATURED COMPANIES
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Transplant IV Biologics and Oral Immunosuppressives specializing in Desensitization and AMR Treatment and Prevention. MORE
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Hormonal imbalance in relation to exercise intolerance and ventilatory inefficiency in chronic heart failure
The Journal of Heart and Lung Transplantation (subscription required)
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Skeletal muscle wasting is associated with altered catabolic/anabolic balance and poor prognosis in patients with chronic heart failure (CHF). A study recently evaluated catabolic and anabolic abnormalities in relation to disease severity in CHF patients. Researchers concluded enhanced catabolic status is significantly associated with exercise intolerance, ventilatory inefficiency and chronotropic incompetence in CHF patients, suggesting a significant contributing mechanism to their limited functional status.
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Characterization and quantification of porcine circulating endothelial cells
Xenotransplantation (subscription required)
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Endothelial damage is a critical step in the development of (xeno) transplantation-related and cardiovascular pathology. In humans, the amount of circulating endothelial cells (CEC) correlates to disease intensity and functions as a valuable damage marker. While (xeno) transplantation and cardiovascular research is regularly performed in porcine models, the paucity of antibodies against porcine endothelium epitopes hinders the use of CEC as damage marker. A recent study aimed to develop a method for porcine CEC detection using anti-human antibodies against porcine endothelium epitopes.
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Donor risk factors, retrieval technique, preservation and ischemia/reperfusion injury in pancreas transplantation
Current Opinion in Organ Transplantation (subscription required)
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Pancreas transplantation is still hampered by a high incidence of early graft loss, and organ quality concerns result in high nonrecovery/discard rates. Demographic donor characteristics, surgical retrieval strategy, preservation fluid and ischemia time are crucial factors in the process of organ selection and are discussed in this review.
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