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SOCIETY NEWS

Take part in AST's Pay it Forward Campaign and enter to win an iPad or AST Bucks
AST
The greatest compliment we can receive is a new member referral, so we want to recognize those of you who consistently enhance our society by recruiting new members.

For each new member that you recruit, your name will be entered to win one of three prizes. Additionally, you’ll receive recognition for your efforts at the 2015 American Transplant Congress (ATC), on the AST website, and in the AST eNews. Encourage your colleagues to complete a membership application by April 15, 2015 so that they can register for the ATC at the member discounted registration rate.

Talk to your colleagues about the benefits of AST membership that you find most valuable. By encouraging your colleagues to join today, you’ll both strengthen the transplant community and help each other grow personally and professionally! For further details please visit: http://www.myAST.org/payitforward.
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Free March Webinars
AST
1. Hepatitis C Treatment in Non-liver Solid Organ Transplant Recipients
Tuesday, March 17, 2 p.m. EST.
Register today at www.myAST.org/T3 - free for AST members.
The recent availability of interferon-free, all-oral, antiviral drug combinations to treat of chronic hepatitis C provides an opportunity to revise management algorithms to optimize the care of non-liver transplant candidates and recipients.

2. Monitoring the Alloresponse Before and After Transplantation: 
Tuesday, March 31, 2 p.m. EST.
Register today at www.myAST.org/T3 - free for AST members.
Review the available data on pre- and post-transplant immune monitoring and how incorporating specific tests may help us diagnose, predict, and better treat our transplant recipients.

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UPCOMING EVENTS IN TRANSPLANTATION


Mark your calendar! AST Town Hall and Excellence in Transplantation Reception at ATC
AST
We invite all AST members to attend the AST Town Hall meeting at ATC on Monday, May 4 at 5:45 p.m. This meeting provides a forum for open discussion between AST membership and leadership about key issues impacting our society and field of transplantation. In addition, we'll announce the Board of Directors election results, welcome the first group of FAST inductees, honor AST volunteer leaders, and award the 2015 research grants.
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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


OTHER NEWS


Call for Council Nominations from the Alliance
Organ Donation and Transplantation Alliance
The Organ Donation and Transplantation Alliance (The Alliance) is seeking nominations of individuals to serve on the newly created Leadership and Innovation Council. This Council will be composed of not only organ donation and transplantation industry leaders but also innovative leaders from other industries including, but not limited to, higher education, healthcare, technology and business. The Council will facilitate leadership networking and innovative idea exchange, testing and implementation within the organ donation and transplantation community in an effort to save and heal more lives.

Visit http://organdonationalliance.org/education/leadership-council/ to download and complete the form. Forms must be completed and submitted by Friday, March 20. Please contact LeAnn Swanson at lswanson@odt-alliance.org with any questions.

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COMMITMENT TO CARE
Raptor's mission is to develop and commercialize life-altering therapeutics that treat rare, debilitating, and often fatal diseases.
LEARN MORE
Advertise here!

To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.
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TRANSPLANT NEWS


Solid organ transplantation from hepatitis B virus–positive donors: Consensus guidelines for recipient management
American Journal of Transplantation
Use of organs from donors testing positive for hepatitis B virus (HBV) may safely expand the donor pool. The American Society of Transplantation convened a multidisciplinary expert panel that reviewed the existing literature and developed consensus recommendations for recipient management following the use of organs from HBV positive donors. Transmission risk is highest with liver donors and significantly lower with non-liver (kidney and thoracic) donors.
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Renal function in de novo liver transplant recipients receiving different prolonged-release tacrolimus regimens—The DIAMOND study
American Journal of Transplantation
DIAMOND: multicenter, 24-week, randomized trial investigating the effect of different once-daily, prolonged-release tacrolimus dosing regimens on renal function after de novo liver transplantation. Arm 1: prolonged-release tacrolimus (initial dose 0.2mg/kg/day); Arm 2: prolonged-release tacrolimus (0.15–0.175mg/kg/day) plus basiliximab; Arm 3: prolonged-release tacrolimus (0.2mg/kg/day delayed until Day 5) plus basiliximab. All patients received MMF plus a bolus of corticosteroid (no maintenance steroids).
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Outcomes after heart transplantation for amyloid cardiomyopathy in the modern era
American Journal of Transplantation
We conducted a review of patients undergoing heart transplantation (HT) at our institution for amyloid cardiomyopathy (ACM) between 2008 and 2013. Complete follow-up was available for all patients. Nineteen patients with ACM underwent HT during the study period, accounting for 9.4 percent of all HT performed at our institution during this period. Amyloid subtype was light chain (AL) in 9 patients and transthyretin (ATTR) in 10 (2 wild-type, 7 familial, 1 unknown).
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Racial and ethnic disparities in pediatric renal allograft survival in the United States
Kidney International
This study was undertaken to describe the association of patient race/ethnicity and renal allograft survival among the national cohort of pediatric renal allograft recipients. Additionally, we determined whether racial and ethnic differences in graft survival exist among individuals living in low- or high-poverty neighborhoods and those with private or public insurance.
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Liver sharing and organ procurement organization performance
Liver Transplantation
Whether the liver allocation system shifts organs from better performing organ procurement organizations (OPOs) to poorer performing OPOs has been debated for many years. Models of OPO performance from the Scientific Registry of Transplant Recipients make it possible to study this question in a data-driven manner. We investigated whether each OPO's net liver import was correlated with 2 performance metrics [observed to expected (O:E) liver yield and liver donor conversion ratio] as well as 2 alternative explanations [eligible deaths and incident listings above a Model for End-Stage Liver Disease (MELD) score of 15].
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    HLA epitopes as viewed by antibodies: What is it all about? (American Journal of Transplantation via PubMed)
Free March Webinars (AST)
Renal function in de novo liver transplant recipients receiving different prolonged-release tacrolimus regimens—the DIAMOND study (American Journal of Transplantation)
Serum sodium and survival benefit of liver transplantation (Liver Transplantation)
OPTN/SRTR 2013 Annual Data Report: Liver (American Journal of Transplantation)

Don't be left behind. Click here to see what else you missed.
 



AST eNews

Colby Horton, Vice President of Publishing, 469.420.2601
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Julie Bernhard, Executive Editor, 469.420.2647  
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