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AST
A number of transplant organizations from around the world continue their partnership to create a second educational webinar for the organ donation and transplantation communities. Our goal is to share experiences to date and respond to your questions about the impact of COVID-19 on organ donation and transplantation.
This second Town Hall was recorded on April 13, 2020. The recording is now available on AST’s YouTube channel. To view the recording, click here.
AST
It is with great regret that we inform you the in-person ATC in Philadelphia must be canceled. We thank all of you for your patience and understanding while we have evaluated the status of ATC 2020. To view the full status on ATC 2020 and FAQ's, click here.
We are diligently working to transform our in-person program to ATC 2020’s Virtual Program that will showcase the latest research and advances made by the transplant community over the past year. More information will be provided on this in the coming weeks.
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AST
With the growing concern about the Coronavirus (COVID-19), the AST has published FAQ pages and other resources for both professionals and patients.
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Promoted by
Veloxis Pharmaceuticals
Now you can see the different ways that different formulations are released and absorbed in the gastrointestinal system. You’ll also have the opportunity to explore comparative pharmacokinetic results in rapid metabolizers, efficacy data over 2 years, and safety information.
Watch Video
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AST
Information regarding COVID-19 is changing rapidly. This document will be updated with the evolving issues related to medication access and drug shortages/supply chain issues within the United States of America during the pandemic.
Veloxis Pharmaceuticals
 Explore this phase 3 randomized, double-blind, double-dummy, multicenter, multinational, non-inferiority trial published in the American Journal of Transplantation. The study examined treatment failures defined as BPAR, graft failure, death, and delayed graft
function at 3 months and 12 months.
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AST
CareDx, Inc., in collaboration with the AST Research Network, is seeking proposals for "Utility of Donor Derived Cell Free DNA."
The submission deadline has been extended to June 19, 2020, to support the needs of transplant professionals during the COVID-19 pandemic. The start of the grant term will remain October 1, 2020.
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AST
Like most non-profit organizations, the AST has many valuable relationships that contribute to its continued growth and sustainability. To give our partners the opportunity to showcase their current initiatives and news, the AST posted its April 2020 Partner's Blog.
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| Public Policy and Advocacy Updates
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AST
The AST endorsed efforts by Sen. Baldwin (D-WI) in a letter to applaud her introduction of S. 3584, the Workers First Protection Act. The bill seeks to the issuance of a comprehensive emergency temporary standard to protect workers against the COVID-19 pandemic.
The AST drafted a letter to the Majority and Minority Leaders regarding the critical need for PPE and other resources to effectively combat the COVID-19 virus.
The Society joined more than 200 other organizations in a letter to the Administration asking for immediate action to alleviate the critical shortage across the nation of ventilators and personal protective equipment resulting from the COVID-19 pandemic.
The AST Joined a number of organizations in a letter to request significant long-term investment in public health infrastructure that is critical to support the public health system as it rebuilds from the COVID-19 crisis and prepares for future public health demands.
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TruGraf® - The 1st and only non-invasive test to rule out “silent" subclinical rejection in stable kidney transplant recipients
The only test to be reimbursed as an alternative to surveillance biopsies
Developed by Clinicians for Clinicians
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AST
As the House and Senate develop additional stimulus and relief legislative packages, it is critical that increased funding for a greater production of supplies and PPE becomes available to protect the medical community. It is important that our legislators know that this is critical for their constituents. Please contact your legislators today.
AST
The Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act would extend Medicare coverage of immunosuppressive drugs for kidney transplant recipients, which is currently limited to just 36 months. Please take a moment to contact your Members of Congress about this important legislation. Contact Congress Today
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Promoted by
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AST
Transplant professionals have increasing demands on their time. Finding time in one’s day to attend conferences or to read journals is challenging. Transplant in 10 is intended to provide transplant professionals with short, easily accessible videos on key and updated topics in 10 minutes.
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| Upcoming Education Events
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AST
The survival advantage of pancreas after kidney transplant
May 4, 2020 | 2 pm ET | Online Activity
For more information, click here.
Signaling through the Inhibitory Fc Receptor FcgRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity
May 19, 2020 | 2 pm ET | Online Activity
For more information, click here.
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Journal of Hepatology via ScienceDirect
Recurrence of primary biliary cholangitis (PBC) after liver transplantation (LT) is frequent and able to impair graft and patient survival. Ursodeoxycholic acid (UDCA) is the current standard therapy for PBC. This study investigated the effect of preventive exposure to UDCA on the incidence and long-term consequences of PBC recurrence after LT.
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American Journal of Kidney Diseases
For weeks we watched as Wuhan, China was ravaged by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), wondering what the future had in store for
us. On Jan. 21, 2020, the first case of COVID-19 on U.S. soil was identified 20 miles north of
Seattle in the town of Everett, Wash. On Friday Feb. 28, the nation's first reported
death due to COVID-19 infection was disclosed, followed by the second mortality case a mere 48
hours later. Both were end-stage renal disease (ESRD) patients dialyzing with Northwest Kidney
Centers in our ambulatory clinics, and subsequently under the care of our Hospital Services
team. Over the course of that weekend, our organization was brought to the forefront of the
COVID-19 pandemic, mandating an immediate and coordinated response.
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The Journal of Heart and Lung Transplantation
The number of potential pediatric heart transplant recipients continues to exceed the number of donors, and consequently the waitlist mortality remains significant. Despite this, around 40 percent of all donated organs are not used and are discarded. This document evaluates factors responsible for discarding donor hearts and makes recommendations regarding donor heart acceptance. The aim of this statement is to ensure that no usable donor heart is discarded, wait-list mortality is reduced, and post-transplant survival is not adversely impacted.
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Kidney International
The outcome of SARS-CoV2 infection in patients who have received a kidney allograft and are being treated with immunosuppression is unclear. This article describes 20 kidney transplant recipients, median age of transplant 13 years, baseline eGFR 36.5 with SARS-CoV2 induced pneumonia.
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Banff Digital Pathology Working Group
The Banff Digital Pathology Working Group (DPWG) was formed in the time leading up to and during the joint American Society for Histocompatibility and Immunogenetics (ASHI)/Banff Meeting, Sept. 23-27, 2019, held in Pittsburgh, Pa. At the meeting, the 14th Banff Conference, presentations directly and peripherally related to the topic of "digital pathology" were presented; and discussions before, during, and after the meeting have resulted in a list of issues to address for the DPWG. Included are practice standardization, integrative approaches for study classification, scoring of histologic parameters, algorithm classification, and precision diagnosis.
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