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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   April 25, 2014


Scientific retreat of international transplants skin cancer collaborative and skin cancer in organ transplant patients in Europe
American Journal of Transplantation (login required)
The International Transplant Skin Cancer Collaborative is an organization of more than 300 physicians and scientists focused on the study of dermatologic changes following solid organ transplantation. Transplant patients have a 100-fold increased risk of developing skin cancer. In October 2012, ITSCC and its European counterpart Skin Cancer in Organ Transplant Patients Europe held a joint biennial retreat in Essex, Mass., to discuss novel findings in the pathogenesis and management of skin cancer in solid organ transplant recipients. This meeting report is a summary of the novel findings discussed.
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AST + ESOT Joint Meeting: Personalized Transplantation: From New Diagnostics to New Therapeutics
Oct. 17-19
Madrid, Spain

Come to Spain this fall as we explore:
  • New Options to Improve Immunosuppressive Therapy: Belatacept, Anti CD40 trial (ASKP1240), Anti- IL-6 and Tacrolimus formulations
  • Novel Diagnostics: Donor DNA - Biomarker of Graft Injury, In vivo Live Imaging of the Immune Response and Tolerance Profile
  • Novel Targets for Immunosuppression: B-cells, Plasma Cells and Complement
  • Personalized Medicine: Technique and Technology: Sequencing for TCR Repertoire, Pharmacogenetics, Epigenetics and Mixed Chimerism
  • Cellular Strategies to Optimize Long Term Outcomes: T-regs, Mesenchymal Cells, Facilitator Cells
Be a part of the program! Submit your clinical, translational and basic abstracts on Novel Immune Monitoring and/or Diagnostics and Immunosuppression Strategies. Abstract Submission Deadline: Sunday, June 29.

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The Business of Transplantation Webinar Series is back!
Building on the original eight topics in the Business of Transplantation webinar series, a new five-webinar series launches on Wednesday, May 14 at 2 p.m. EST. Read more about the topics and register for the May and June webinars now at The 2014 Business of Transplantation series will cover new SRTR reporting methodologies, OPO finance and quality programs, OPO/transplant center collaborations and healthcare changes.
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UNOS resources on KPD and new kidney allocation system
More than half of the eligible kidney transplant hospitals currently participate in the OPTN KPD Pilot Program, but for those that don’t, a video is now available to provide more information. The video describes the mission and goals of the program, outlines the benefits of the program for hospitals, and explains how the program increases patient access to transplants.  

UNOS also offers  ongoing educational activities (live and on demand) to help transplant professionals begin preparations for the kidney allocation system changes coming later this year.  Visit to access all UNOS resources.

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UCLA Immunogenetics Center

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The University Of Utah Department Of Surgery is seeking applications for a faculty member to join the multi-organ transplant team at the assistant professor level. This is an opportunity to join an expanding program and a cohesive group of transplant surgeons focused on excellence. The candidate should be board certified in general surgery and have completed an ASTS approved transplantation surgery fellowship. Apply here
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To induce or not to induce: a 21st century evaluation of lung transplant immunosuppression's effect on survival
Clinical Transplantation (login required)
The impact of induction immunosuppression on long-term survival in lung transplant recipients remains unclear. Authors of this study sought to evaluate the effect of contemporary induction immunosuppression agents in lung transplant recipients' survival, utilizing national registry data.
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Review: Desensitization in kidney transplantation
Clinical Transplantation (login required)
More than half of the kidney transplant candidates awaiting transplantation are sensitized to human leukocyte antigens. Desensitization to HLAs involves treatment with immunomodulating therapies designed to reduce levels of anti-HLA antibodies in order to make kidney transplantation possible.
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Predictors of post-traumatic psychological growth in the late years after lung transplantation
Clinical Transplantation (login required)
Although lung transplantation improves quality of life, most psychosocial research focuses on adverse psychological and social functioning outcomes. Positive effects, particularly in the late-term years as physical morbidities increase, have received little attention. We provide the first data on a psychological benefit — post-traumatic growth (PTG) — and we focused on long-term survivors.
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Missed last week's issue? See which articles your colleagues read most.

    Survival of recipients of livers from donation after circulatory death who are relisted and undergo retransplant for graft failure (American Journal of Transplantation)
Prolonged immunosuppression preserves nonsensitization status after kidney transplant failure (Transplantation (login required))
Renal function preservation with the mTOR inhibitor, Everolimus, after lung transplant (Clinical Transplantation)
Public attitudes and beliefs about living kidney donation (Transplantation)
Severe muscle depletion predicts postoperative length of stay but is not associated with survival after liver transplantation (Liver Transplantation)

Don't be left behind. Click here to see what else you missed.

Explaining the racial difference in AKI incidence
Journal of the American Society of Nephrology (login required)
African Americans face higher risk of AKI than Caucasians. The extent to which this increased risk is because of differences in clinical, socioeconomic, or genetic risk factors is unknown. Authors evaluated 10,588 African-American and Caucasian participants in the Atherosclerosis Risk in Communities study, a community-based prospective cohort of middle-aged individuals.
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Early hospital readmissions post-kidney transplantation are associated with inferior clinical outcomes
Clinical Transplantation (login required)
Unplanned hospital readmissions are common early post-kidney transplantation. Authors investigated the relationship between early hospital readmissions and clinical outcomes in a single-center retrospective study that included all adult kidney transplant patients between 2004 and 2008 with follow-up to December 2012.
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