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AST
With the growing concern about the Coronavirus (COVID-19), the AST has published FAQ pages and other resources for both professionals and patients.
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AST
On April 27, infectious disease specialists answered some of the common COVID-19 questions of transplant recipients. VIEW VIDEO
AST
Information regarding COVID-19 is changing rapidly. This document will be updated with the evolving issues related to medication access and drug shortages/supply chain issues within the United States of America during the pandemic.
AST
The ATC 2020 Virtual Congress is set to launch May 30, 2020! This year's event will deliver an all-new, OnDemand virtual experience that will bring together professionals working in all aspects of solid organ and tissue transplantation to hear the newest research, connect across disciplines, and advance the specialty.
Attendees can earn up to 149.5 CME, ACPE, ANCC, CEPTC Credit/Contact hours and will have over 1 year of OnDemand session access.
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Veloxis Pharmaceuticals
Now you can see the different ways that different formulations are released and absorbed in the gastrointestinal system. You’ll also have the opportunity to explore comparative pharmacokinetic results in rapid metabolizers, efficacy data over 2 years, and safety information.
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AST
The AST Board of Directors election is now open. If you are an eligible member of the AST, check your email for information on how to vote. More information about the nominees can be found here.
AST
CareDx, Inc., in collaboration with the AST Research Network, is seeking proposals for "Utility of Donor Derived Cell Free DNA."
The submission deadline has been extended to June 19, 2020, to support the needs of transplant professionals during the COVID-19 pandemic. The start of the grant term will remain October 1, 2020.
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Veloxis Pharmaceuticals
 Explore this phase 3 randomized, double-blind, double-dummy, multicenter, multinational, non-inferiority trial published in the American Journal of Transplantation. The study examined treatment failures defined as BPAR, graft failure, death, and delayed graft
function at 3 months and 12 months.
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AST
Visit the AST Member Spotlight page to read about Thomas Schiano's current projects.
Interested in being featured in the AST Member Spotlight? Please contact rpaulin@myast.org for more information.
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AST
The Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients Act would extend Medicare coverage of immunosuppressive drugs for kidney transplant recipients, which is currently limited to just 36 months. Please take a moment to contact your Members of Congress about this important legislation. Contact Congress Today
AST
Transplant professionals have increasing demands on their time. Finding time in one’s day to attend conferences or to read journals is challenging. Transplant in 10 is intended to provide transplant professionals with short, easily accessible videos on key and updated topics in 10 minutes.
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| Upcoming Education Events
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AST
Signaling through the Inhibitory Fc Receptor FcgRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity
May 19, 2020 | 2 pm ET | Online Activity
For more information, click here.
HCV NAT+/- in Thoracic Organ Transplantation: Where Are We Now and What's Next?
May 20, 2020 | 2 pm ET | Online Activity
For more information, click here.
HCV NAT+/- in Abdominal Organ Transplantation: Where Are We Now and What's Next?
May 27, 2020 | 2 pm ET | Online Activity
For more information, click here.
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Labs@HOME is a mobile phlebotomy in-home blood draw service to aid in specimen collection directly from a patient’s home. Clinicians can order and customize a number of infectious disease and transplant-related testing remotely.
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American Journal of Transplantation
In light of changes in donor/recipient case‐mix and increased cold ischemia times under KAS, there is some concern that cPRA 100% recipients might be doing poorly under KAS. We used granular, single‐center data on 109 cPRA 100% deceased donor kidney transplant (DDKT) recipients to study post‐KAS post‐transplant outcomes not readily available in national registry data.
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American Journal of Transplantation
Non‐invasive biomarker profiles of acute rejection (AR) could impact the management of liver transplant (LT) recipients. Peripheral blood was collected following LT for discovery (Northwestern University (NU)) and validation (NIAID CTOT‐14 study). Blood gene profiling was paired with biopsies showing AR or ADNR (acute dysfunction no rejection) as well as stable graft function samples (Transplant eXcellent – TX).
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Journal of the American Society of Nephrology
For the transplant specialist, microbiology represents a series of potential tools with which to probe the human immune system. We assume that, for each pathogen, the immunocompromised host will demonstrate reduced resistance to infection, atypical clinical signs and symptoms, more rapid progression, and greater mortality. There are few data that guide the clinician for modification of immunosuppressive regimens for specific infections. Confronted with novel coronavirus-19 infection (COVID-19), clinicians have strong opinions regarding the best immunosuppressive manipulations on the basis of extensive, but uncontrolled experience with other infections.
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American Journal of Transplantation
The purpose of the STAR 2019 Working Group was to build on findings from the initial STAR report to further clarify the expectations, limitations, perceptions, and utility of alloimmune assays that are currently in use or in development for risk assessment in the setting of organ transplantation. The goal was to determine the precision and clinical feasibility/utility of such assays in evaluating both memory and primary alloimmune risks.
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The Journal of Heart and Lung Transplantation
Donor heart allocation in the United States is managed by United Network for Organ Sharing (UNOS); however, donor heart selection is managed by individual transplant centers. Consequently, donor offer acceptance practice varies significantly: in 2017-2018 the Scientific Registry of Transplant Recipients (SRTR) Offer Acceptance Ratio ranged from 0.22 (less likely than average to accept an offer) to 3.69.1 This study sought to determine if local competition was associated with donor selection practices for adult heart transplantation.
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