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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   May 09, 2014

 




SOCIETY NEWS

Upcoming Free Webinars and Webinars on Demand
AST
The following webinars and journal club are scheduled for May; all are free to AST members and are available on demand after the live air date.
  • Fellows Webinar on Donor Acceptance, Wed., May 7; register online
  • Business of Transplantation Webinar on CUSUM and Bayesian Charts (new SRTR reporting methodologies); register online
  • Webinar on Role of HLA Testing in Pre- and Post-transplant Monitoring for SOT, Tues., April 22; register online
  • Journal Club on Risk of End-Stage Renal Disease Following Live Kidney Donation, Thurs., May 29; register online
AST also offers popular webinars and journal clubs on demand at www.myAST.org/T3, www.myAST.org/content/fellows-live-webinar-series, and www.myAST.org/journalclub.
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AST endorses Capitol Hill legislation establishing beneficiary equity in the hospital readmission program
AST
The AST has been working closely with the office of Congressman Jim Renacci (R-OH) to garner support for his legislation (HR 4188) that seeks to exempt organ transplantation, ESRD, and other targeted conditions from classification as an admission for purposes of penalties under the Affordable Care Act (ACA). AST believes this legislative proposal is an essential and necessary step for protecting certain patient populations that would otherwise be compromised under the current law policy for hospital readmissions. The Society is working to garner cosponsors, support from Leadership in the House of Representatives as well as a Senate champion to introduce companion legislation. Read the letter here or read a complete analysis of the legislation here.
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ATC 2015: Call for Programs Open!
AST
The 2015 American Transplant Congress Program Planning Committee is now accepting program proposals for scientific sessions to be held May 2-6, 2015 in Philadelphia. Participate in the call for programs and share your experience and knowledge with leaders in the transplantation community from across the globe. The deadline to submit proposals is May 30, 2015. Click here to submit your program proposal.
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TRANSPLANT NEWS


The management of antibody-mediated rejection in the first presensitized recipient of a full-face allotransplant
American Journal of Transplantation (login required)
Authors report on the management of the first full-face transplantation in a sensitized recipient with a positive preoperative crossmatch and subsequent antibody-mediated rejection (AMR). The recipient is a 45-year-old female who sustained extensive chemical burns, with residual poor function and high levels of circulating anti-HLA antibodies. With a clear immunosuppression plan and salvage options in place, a full-face allotransplant was performed using a crossmatch positive donor.
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Preoperative Cylex assay predicts rejection risk in patients with kidney transplant
Clinical Transplantation (login required)
The ImmuKnow assay measures cell-mediated immunity by quantifying ATP release from CD4+ T-cells in peripheral blood. Herein, authors hypothesized that this assay could predict complications associated with over-/under-immunosuppression in patients with kidney transplant.
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Recurrence of hepatocellular carcinoma: Importance of mRECIST response to chemoembolization and tumor size
American Journal of Transplantation (login required)
Determining risk for recurrence of hepatocellular carcinoma following liver transplantation is an important clinical need. Authors assessed consecutive patients who underwent LT for HCC following sequential transarterial chemoembolization. Treatment response was assessed using modified response evaluation criteria in solid tumors (mRECIST) categories: complete response, partial response, stable disease and progressive disease. Cox proportional hazard models were used to predict HCC recurrence.
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Survey: Education and informed consent about increased risk donor kidneys
Transplant Infectious Disease (login required)
Transplant providers must understand the definition of increased risk donor organs to effectively educate transplant candidates and obtain informed consent. This study surveyed non-physician providers from 20 transplant centers about their educational and informed consent practices of IRD kidneys.
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Survey: Impact of repeat testing of living kidney donors within 14 days of the transplant procedure
Transplant Infectious Disease (login required)
A transmission of human immunodeficiency virus from a live kidney donor prompted recommendations by the New York State Department of Health and the US Centers for Disease Control and Prevention that all live donors undergo additional screening for HIV, hepatitis B virus and hepatitis C virus within 7–14 days of the donation procedure. There are concerns that re-screening will result in delays and cancelled transplants.
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Featured Advertisers


UCLA Immunogenetics Center


The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
University of Utah - Multi-Organ Transplant Surgeon

The University Of Utah Department Of Surgery is seeking applications for a faculty member to join the multi-organ transplant team at the assistant professor level. This is an opportunity to join an expanding program and a cohesive group of transplant surgeons focused on excellence. The candidate should be board certified in general surgery and have completed an ASTS approved transplantation surgery fellowship. Apply here
2013 USIEC Excellence Award Winner

OTTR is pleased to be recognized for Excellence in Software by USIEC and for receiving CIBMTR Certification. Please contact us at ottr.com to see how we can help you.


Study: Artificial hearts may help patients awaiting transplants
By Joy Burgess
Although experts still consider artificial hearts risky, recent research found that artificial hearts might prove helpful to patients with heart failure while they await heart transplants. Patients with severe heart failure — specifically those dealing with end-stage cardiomyopathy — may not live long enough to receive a heart transplant from an organ donor, but an artificial heart can help prolong life until a transplant becomes available.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    First-in-human study of the safety and efficacy of TOL101 induction to prevent kidney transplant rejection (American Journal of Transplantation)
Procurement for visceral organ transplantation: where to cannulate and how to perfuse? (Current Opinion in Organ Transplantation)
Acute rejection linked to ketoconazole (Renal & Urology News)
Subnormothermic machine perfusion for ex vivo preservation and recovery of the human liver for transplantation (American Journal of Transplantation)
Diarrhea caused by viruses in transplant recipients (Transplant Infectious Disease)

Don't be left behind. Click here to see what else you missed.


A multi-institutional study of malignancies after heart transplantation and a comparison with the general United States population
The Journal of Heart and Lung Transplantation (login required)
The purpose of these studies was to determine the incidence and survival of patients with specific malignancies with respect to age and transplant year and to compare the data with the normal non-transplant population.
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Need a lung? Humanized pig organs for transplant will be available in the near future
Tech Times
J. Craig Venter announced its team up with Lung Biotechnology Inc. of United Therapeutics Corp. to cultivate pig lungs that could possibly address the need for organ transplant for patients with later stages of lung disease. Synthetic Genomics Inc. is a private company that develops and commercializes genomic advancements in different industries. The companies entered into a multi-year agreement to research and develop humanized pig lungs with the use of synthetic genomic technology. The collaboration aims to develop lungs and other organs for humans in need of transplants. If successful, SGI will earn incentives and royalties from the agreement.
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Academic potential and cognitive functioning of long-term survivors after childhood liver transplantation
Pediatric Transplantation (login required)
This cross-sectional study assessed intellect, cognition, academic function, behaviour, and emotional health of long-term survivors after childhood liver transplantation. Eligible children were more than five years post-transplant, still attending school, and resident in Queensland. Hearing and neurocognitive testing were performed on 13 transplanted children and six siblings including two twin pairs where one was transplanted and the other not.
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Histologically proven non-alcoholic fatty liver disease and clinically related factors in recipients after liver transplantation
Clinical Transplantation (login required)
Non-alcoholic fatty liver disease affects a substantial proportion of the world population, and its prevalence has been increasing. This study was aimed at evaluating the prevalence and peri-transplant risk factors for post-liver transplantation NAFLD.
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Association between cell-derived microparticles and adverse events in patients with nonpulsatile left ventricular assist devices
The Journal of Heart and Lung Transplantation
Continuous-flow left ventricular assist devices expose blood cells to high shear stress, potentially resulting in the production of microparticles that express phosphatidylserine and promote coagulation and inflammation. In this prospective study, we attempted to determine whether PS+ microparticle levels correlate with clinical outcomes in LVAD-supported patients.
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