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AST
Earlier this month, several members of the AST leadership attended the White House Organ Summit, an event focused on key actions to reduce the waiting list and saving lives. Four AST commitments were specifically highlighted, and two were mentioned as part of the Summit, showing the AST's leadership in this area.
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ODRC, AOPO
The Organ Donation Research Consortium (ODRC) with additional support from the Association of Organ Procurement Organizations (AOPO) is pleased to offer up to $40,000 in funding to member(s) conducting basic, translational, or clinical research specifically related to the organization's mission to advance the science of organ donation. [Learn more]
AST
Check out AST's archived webinars and journal clubs, and watch educational content when it's convenient for you. AST also offers a variety of resources for different transplant specialties, all available on our easy-to-search website.
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The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
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AST
Sept. 20, 2016 2 p.m. Online Activity
For more information: myast.org/education/webinars/t3
AST
AST & ESOT Basic Science Meeting
November 10 - 12, 2016
Sheraton Ft. Lauderdale at Cypress Creek, Ft. Lauderdale, FL
AST ESOT ABSTRACT SUBMISSION SITE NOW OPEN
Submission Deadline is: June 26, 2016
Registration is now open! Don't miss out, register today!
The Federation of Clinical Immunology Societies
June 22-25, 2015 | Boston, MA
For more information: myast.org/meetings/focis-2016
AST: Fellows Symposium 2016
Sept. 23-25, 2015
Hilton DFW Lakes Executive Conference Center, Grapevine, TX
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Predicting your "Observed to Expected" ratios
by cohort, by patient, and by risk factor
Wait List Management
Ensuring your wait listed patients are transplant-ready
one phone call at a time.
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American Journal of Transplantation
In this paper, we have reviewed the literature and report on kidney donors that are currently used at relatively low rates. Kidneys from donors with acute kidney injury (AKI) seem to have outcomes equivalent to those from donors without AKI, provided one can rule out significant cortical necrosis. Kidneys from donors with preexisting diabetes or hypertension may have marginally lower aggregate survival but still provide patients with a significant benefit over remaining on the wait list.
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American Journal of Transplantation
For some patient subgroups, human immunodeficiency virus (HIV) infection has been associated with worse outcomes after kidney transplantation (KT); potentially modifiable factors may be responsible. The study goal was to identify factors that predict a higher risk of graft loss among HIV-positive KT recipients compared with a similar transplant among HIV-negative recipients. In this study, 82 762 deceased donor KT recipients (HIV positive: 526; HIV negative: 82 236) reported to the Scientific Registry of Transplant Recipients (SRTR) (2001–2013) were studied by interaction term analysis.
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Liver Transplantation
Identification of which liver transplant (LT) candidates with severe kidney injury will have full recovery of renal function after liver transplant alone (LTA) is difficult. Avoiding unnecessary simultaneous liver-kidney (SLK) transplant can optimize use of scarce kidney grafts. Incorrect predictions of spontaneous renal recovery after LTA can lead to increased morbidity and mortality.
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Transplant International
Metabolic syndrome (MS) has been associated with proteinuria and reduced glomerular filtration rate. Immunosuppressive agents increase the incidence of traditional risk factors for cardiovascular disease (CVD) and have known effects on MS components after kidney transplantation. The purpose of this meta-analysis is to evaluate the impact of MS on relevant outcomes after kidney transplantation.
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Transgenic Research
The domestic pig shares many genetic, anatomical and physiological similarities to humans and is thus considered to be a suitable organ donor for xenotransplantation. However, prior to clinical application of porcine xenografts, three major hurdles have to be overcome: (1) various immunological rejection responses, (2) physiological incompatibilities between the porcine organ and the human recipient and (3) the risk of transmitting zoonotic pathogens from pig to humans. With the introduction of genetically engineered pigs expressing high levels of human complement regulatory proteins or lacking expression of α-Gal epitopes, the HAR can be consistently overcome. However, none of the transgenic porcine organs available to date was fully protected against the binding of anti-non-Gal xenoreactive natural antibodies.
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Liver Transplantation
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7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063
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