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AST TIRN research grant request for proposals now open
The AST Transplantation and Immunology Research Network (TIRN) research grants program supports fellows, junior faculty, and allied health professionals by funding innovative research in basic, clinical, and translational science. A limited number of grants will be awarded for research projects beginning July 1, 2016. The request for proposals is open now at Applications must be completed by 11:59 PM Pacific Standard Time on Sunday, Nov. 1, 2015. For more information, visit or email
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Education and Clinical Tools for the Independent Living Donor Advocate: Webinar July 15
“Living Kidney Donation A to Z: Understanding the Basics,” the next webinar in the Education and Clinical Tools for the Independent Living Donor Advocate (ILDA) webinar series, takes place Wednesday, July 15 at 1 p.m. EDT. The entire nine-webinar series developed by the AST Live Donor Community of Practice is FREE to AST members and their associates - just register with an AST member username and password at

Non-members can purchase access to all nine webinars for just $200. Eligible non-members can join the AST as a non-doctoral member and the webinar series is included in their $90 annual dues. Find out more at

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You care about your transplant patients. And so do we. That’s why we’re introducing Astellas Cares—a new program that offers you customized tools, educational resources, and comprehensive support to help your patients care for their health. To register, visit today.

QAPI Adverse Events: Webinar July 8
Join us and ASTS on Wednesday, July 8 at Noon ET for the fifth installment of a monthly webinar series designed and presented by the Centers for Medicare and Medicaid Services. This webinar provides an in-depth review of what Adverse Events are and how Adverse Events can be identified, documented, and acted upon in order to prevent future re-occurrences. Register today!

The content of this presentation is determined independently by CMS without input or endorsement from either the ASTS or AST. Both societies appreciate CMS providing this information to the transplant community and are pleased to facilitate that process.

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  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE


AST Fellows Symposium - Registration now open!
The AST Fellows Symposium on Transplantation is the premier meeting for those entering the exciting field of solid organ transplantation. Special Announcement: Travel grants are now an AST member benefit. Travel grants are only awarded to attendees who are sponsored by an AST member in good standing. Each AST member may sponsor up to two attendees: one from the member’s institution, and one from another institution. For more information on registration eligibility and travel grants, please visit
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ASHI 41st Annual Meeting
Sept. 28 - Oct. 2, 2015 | Savannah, GA
For more information:

2015 Banff/CST Joint Meeting
Oct. 5-10, 2015 | Vancouver
For more information:

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  Missing or Broken Doppler Probes?

VTI’s disposable intraoperative Doppler probes are ready to verify technical results. There’s no longer the need to perform sterilization that frequently causes irreversible damage to the traditional Doppler probes. Advantages include fewer replacements of conventional Doppler probes damaged during sterilization, OR time saved, and a reduction in specialty procedures.


Successful transplantation of kidneys from elderly circulatory death donors by using microscopic and macroscopic characteristics to guide single or dual implantation
American Journal of Transplantation
Most kidneys from potential elderly circulatory death (DCD) donors are declined. We report single center outcomes for kidneys transplanted from DCD donors over 70 years old, using preimplantation biopsy Remuzzi grading to inform implantation as single or dual transplants. Between 2009 and 2012, 43 single transplants and 12 dual transplants were performed from elderly DCD donors.
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Racial and ethnic disparities in access to and utilization of living donor liver transplants
Liver Transplantation
Living donor liver transplantation is a comparable alternative to deceased donor liver transplantation and can mitigate the risk of dying while waiting for transplant. Although evidence exists of decreased utilization of living donor kidney transplants among racial minorities, little is known about access to LDLT among racial/ethnic minorities. We used Organ Procurement and Transplantation Network/United Network for Organ Sharing data from Feb. 27, 2002 to June 4, 2014 from all adult liver transplant recipients at LDLT-capable transplant centers to evaluate differential utilization of LDLTs based on race/ethnicity.
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.

Arterial hypertension in children with hemolytic uremic syndrome after kidney transplantation
Pediatric Transplantation
The development of arterial hypertension after KTX is a well-known complication. HUS is a systemic disease associated with arterial hypertension during long-term follow-up. Our goal was to report on the severity of arterial hypertension after KTX in patients with typical and atypical HUS. We analyzed the course of 197 patients with HUS, of which 22 (n = 10 with typical HUS; n = 12 with atypical HUS) developed ESRF and received KTX as renal replacement therapy.
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Nox2 is a mediator of ischemia reperfusion injury
American Journal of Transplantation
Delayed graft function (DGF) results from ischemia-reperfusion injury (IRI) and the generation of reactive oxygen species. We hypothesized that NADPH oxidase 2 (Nox2) plays an important role in pathways leading to DGF. We tested this hypothesis in vitro, in an animal model of IRI using wild type and Nox2−/− mice, and in patients with DGF.
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Kidney transplantation in patients with severe preoperative hypertension
Clinical Transplantation
Severe systemic hypertension is a risk factor for perioperative cardiovascular complications; however its impact at the time of kidney transplantation is not well defined. A retrospective cohort study of adult kidney-only transplant recipients between 10/09-12/12 was performed to examine outcomes between patients with (n=111) and without (n=98) severe preoperative HTN defined as SBP greater than 180 or DBP greater than 110 mmHg.
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Missed last week's issue? See which articles your colleagues read most.

    New York has a liver problem, with no easy solution (Capital)
New AST blog post: Regenerative Medicine in the White House (AST)
Transmission of hepatitis C virus from organ donors despite nucleic acid test screening (American Journal of Transplantation)
Increasing the number of organ transplants in the United States by optimizing donor authorization rates (American Journal of Transplantation)

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Colby Horton, Vice President of Publishing, 469.420.2601
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Julie Bernhard, Executive Editor, 469.420.2647  
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