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Home    About AST    Education    Meetings & Events    Public Policy    Contact Us   July 04, 2014

 


SOCIETY NEWS


ASN plans early program on transplantation in cooperation with AST
at Kidney Week 2014

AST
In recent years, there have been important advances in the field of kidney transplantation that will impact the care of the kidney transplant recipient. This program provides an interactive, case-based overview of exciting advances in kidney transplantation, with a focus upon specific populations, complications, and ethical issues. Nephrologists with an interest in transplantation, transplant physicians, and trainees in the nephrology are encouraged to attend this program. Get full program details and register here.
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Education on demand at www.myAST.org/education
AST
Find the educational content you need quickly and easily on the reorganized education page of the AST website. Find archives of past webinars and journal clubs, along with links to guidelines, directories, and other resources.
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Don't forget to vote!
AST
Eligible AST members are encouraged to cast their votes for the AST Board of Directors, as well as various bylaw revisions, at http://www.myast.org/content/ast-board-elections-2014-instructions. The voting site will prompt you to log in to the AST website where you will find more detailed information. Voting will end on July 29, 2014, at 5 p.m. PST.
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AST at WTC


RSVP for the AST Town Hall Meeting & Excellence in Transplantation Reception at the 2014 WTC
AST
AST members are invited to take part in the annual member's business meeting, delivered in an exciting interactive town hall format. The Town Hall will take place during the upcoming World Transplant Congress (WTC) on Tuesday, July 29, 2014 at 5:45 PM on the second floor foyer of the Moscone West Convention Center. Join your colleagues and AST leadership to discuss the challenges and opportunities in the field of transplantation, learn how AST is positioned to meet these challenges/opportunities, and provide your feedback in shaping the future of the AST.

Immediately following the town hall, enjoy a casual gathering at the AST Excellence in Transplantation Reception, also on the second floor foyer of the Moscone West Convention Center. Indulge in delectable libations and hors d’oeuvres as you mingle with friends, award and grant recipients, and supporters.

Click here to submit your R.S.V.P. to attend both the town hall and reception. Should you have any questions, please do not hesitate to contact the AST staff at info@myAST.org or (856) 439-9986.

We look forward to seeing you in San Francisco!

These events made possible in part by Sanofi and Veloxis Pharmaceuticals

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UPCOMING EVENTS IN TRANSPLANTATION


Registration now Open for the AST 2014 Fellows Symposium
AST
September 19-21, 2014
Grapevine, Texas

Calling all Fellows and Trainees in transplantation! Join us this September for the AST Fellows Symposium, a highly popular educational meeting for young professionals starting a career in transplantation or immunology. Featuring an in-depth and interactive study of clinical transplantation, basic transplant immunobiology, and translational science in an informal setting, the Fellows Symposium provides important insights into career development and exceptional access to expert faculty. A limited number of travel grants are available for clinical and research fellows, and residents and trainees with an interest in solid organ transplantation. Register now!

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COMMITMENT TO CARE
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TRANSPLANT NEWS


Liver transplantation and cirrhotomimetic hepatocellular carcinoma: Classification and outcomes
Liver Transplantation (login required)
Liver transplantation has become the standard-of-care treatment for hepatocellular carcinoma (HCC) that falls within certain size and numerical criteria for patients with cirrhosis. Cirrhotomimetic (CMM) HCC is an uncommon growth pattern that infiltrates cirrhotic parenchyma, can become extensive in size, and can evade detection via radiological studies. Liver transplant outcomes for this type of HCC are not well reported but generally are considered to be poor. Researchers wished to better describe this variant of HCC in explanted livers, derive a classification system for this tumor type, and assess the outcomes of liver transplantation for this tumor variant.
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Tacrolimus dosage requirements in lung transplant recipients
receiving antifungal prophylaxis with voriconazole followed by itraconazole: A preliminary prospective study

Clinical Transplantation (login rquired)
Concomitant administration of the triazole antifungals, voriconazole or itraconazole, with tacrolimus can result in significant drug interaction in the transplant recipient. Limited published information exists regarding tacrolimus dosing when transitioning from voriconazole to itraconazole. The objective of this study was to evaluate the extent of the drug interaction with antifungal prophylaxis using voriconazole followed by a change to itraconazole in lung transplant recipients receiving tacrolimus.
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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


Perioperative complications in liver transplantation using donation after cardiac death grafts: A propensity-matched study
Liver Transplantation (login required)
Donation after cardiac death (DCD) is an important source for expanding the donor pool for liver transplantation (LT). Although the long-term outcomes of LT using DCD grafts have been extensively studied, perioperative complications related to DCD grafts are rarely reported. The aim of this study was to determine whether DCD grafts were associated with a higher incidence of postreperfusion complications and worse outcomes in adult LT patients.
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Decision making in liver transplantation — limited application of the liver donor risk index
Liver Transplantation (login required)
The liver donor risk index (LDRI), originally developed in 2006 by Feng et al. and since modified, is a method of evaluating liver grafts from deceased donors through the determination of the relative risk of graft failure after transplantation. Online and paper surveys about attitudes and practices regarding decision making in liver transplantation and the role of the LDRI were sent to liver transplant physicians.
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Concomitant tricuspid valve surgery during implantation of continuous-flow left ventricular assist devices: A Society of Thoracic Surgeons database analysis
The Journal of Heart and Lung Transplantation
Performing concomitant tricuspid valve procedures (TVPs) in left ventricular assist device (LVAD) patients with significant pre-operative tricuspid regurgitation (TR) is controversial, and no studies before the following have been large enough to definitively guide therapy.
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'Supercooling' technique may preserve transplant organs longer
Fox News
A new technique may help preserve transplantable organs for days, Nature World News reported. The "supercooling" method of preserving transplant organs was developed by researchers at Massachusetts General Hospital (MGH) in Boston, to help decrease the cost of organ transplants and increase the number of successful organ matches.
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Bone marrow transplantation shows potential for treating adults with sickle cell disease
Medical Xpress
Use of a lower intensity bone marrow transplantation method showed promising results among 30 patients (16-65 years of age) with severe sickle cell disease, according to a study in the July 2 issue of JAMA. Myeloablative (use of high-dose chemotherapy or radiation) allogeneic hematopoietic stem cell transplantation (HSCT; receipt of hematopoietic stem cells "bone marrow" from another individual) is curative for children with severe sickle cell disease, but associated toxicity has made the procedure prohibitive for adults. The development of nonmyeloablative conditioning regimens (use of lower doses of chemotherapy or radiation to prepare the bone marrow to receive new cells) may facilitate safer application of allogeneic HSCT to eligible adults.
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New blood test could replace biopsies in predicting heart transplant rejection
By Karen Zabel
For years, tissue biopsy has been regarded as the gold standard for predicting the potential for heart transplant rejection, but now researchers from Stanford say they've developed a blood test that is able to predict rejection weeks or even months earlier than that technique. The Stanford researchers also indicate the new test outperforms another rejection prediction blood test called Allomap "by a substantial margin."
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Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts
Transplant Immunology
In living donor liver transplantation, the biological organ age of the donated allograft is unknown in young patients who receive grafts from older donors. Few studies have focused on the effects of aging on allografts in the state of tolerance. The purpose of this study was to assess the biological organ age of liver grafts.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    OPTN/UNOS Releases Concept Document on Alternatives for Liver Allocation (AST)
An analysis of pancreas transplantation outcomes based on age groupings — an update
of the UNOS Database
(Clinical Transplantation)
Optical coherence tomography for the evaluation of asymmetric cardiac allograft vasculopathy in a child (Pediatric Transplantation)
OPTN/UNOS Board approves initial policies regarding limb and face transplantation, new policies for pediatric heart allocation (AST)

Don't be left behind. Click here to see what else you missed.
 



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