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Home    About AST    Education    Meetings & Events    Public Policy    Contact Us   July 18, 2014

 


SOCIETY NEWS


Long Time Executive at American Society of Transplantation (AST) Announces Retirement
AST
The AST recently announced that Susan Nelson will be retiring as Executive Vice President later this year. Nelson, who has served in her leadership role since 1994, played a crucial part in the organization and proliferation of AST during her tenure, working with the Board of Directors to shape the society into the industry-leading voice that it is today. Libby McDannell will take over as Executive Vice President of the American Society of Transplantation on October 1, 2014.
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AST at WTC


AST Town Hall Meeting & Reception: Many voices, one goal
AST
AST members are invited to attend a Town Hall meeting at the upcoming World Transplant Conference (WTC) on Tuesday, July 29 at 5:45 PM on the second floor foyer of the Moscone West Convention Center. The Town Hall will provide a forum for open discussion between the membership and the leadership about key issues impacting the Society and field of transplantation, and how the Society is positioned to address those key issues. In addition, we'll announce the Board of Directors election results, recognize and honor AST volunteer leadership, and award the 2014 research grants.

Immediately following the town hall, enjoy a casual gathering at the AST Excellence in Transplantation Reception, also on the second floor foyer of the Moscone West Convention Center. Indulge in delectable libations and hors d'oeuvres as you mingle with friends, award and grant recipients, and supporters.

To submit your R.S.V.P. to attend both the town hall and reception, click here. Should you have any questions, please do not hesitate to contact the AST staff at info@myAST.org or (856) 439-9986.

We look forward to seeing you in San Francisco!

These events made possible in part by Dompé, Sanofi and Veloxis Pharmaceuticals

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UPCOMING EVENTS IN TRANSPLANTATION


Only two weeks left to register for the AST 2014 Fellows Symposium
AST
September 19-21, 2014
Grapevine, Texas

Join us this September for the AST Fellows Symposium, a highly popular educational meeting for young professionals starting a career in transplantation or immunology. Featuring an in-depth and interactive study of clinical transplantation, basic transplant immunobiology, and translational science in an informal setting, the Fellows Symposium provides important insights into career development and exceptional access to expert faculty. A limited number of travel grants are available for clinical and research fellows, and residents and trainees with an interest in solid organ transplantation. Register now!

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COMMITMENT TO CARE
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.
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Save the Date for the Cutting Edge of Transplantation
Immunity and Inflammation: Engineering Cell, Gene, and Drug Therapies

AST
February 5-7, 2015
Sheraton Wild Horse Pass – Chandler, AZ

Make plans to attend this high-energy, intimate meeting featuring sessions on:
  • A Critical Review of Cell Therapies
  • Whatever Happened to Gene Therapy?
  • Organ Repair and Regeneration, and Organ Generation
  • Drug Development and Rediscovering Pathways
  • In vitro, In vivo, and In silico: Are We Done with Animal Models?

Website and call for basic, clinical and translational abstracts coming soon!

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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


TRANSPLANT NEWS


Dialysis facility and network factors associated with low kidney transplantation rates among United States dialysis facilities
American Journal of Transplantation (log in required)
Variability in transplant rates between different dialysis units has been noted, yet little is known about facility-level factors associated with low standardized transplant ratios (STRs) across the United States End-stage Renal Disease (ESRD) Network regions. Researchers analyzed Centers for Medicare & Medicaid Services Dialysis Facility Report data from 2007 to 2010 to examine facility-level factors associated with low STRs using multivariable mixed models. Among 4098 dialysis facilities treating 305 698 patients, there was wide variability in facility-level STRs across the 18 ESRD Networks.
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Quantifying the risk of incompatible kidney transplantation: A multicenter study
American Journal of Transplantation (log in required)
Incompatible live donor kidney transplantation (ILDKT) offers a survival advantage over dialysis to patients with anti-HLA donor-specific antibody (DSA). Program-specific reports (PSRs) fail to account for ILDKT, placing this practice at regulatory risk. Researchers collected DSA data, categorized as positive Luminex, negative flow crossmatch (PLNF), positive flow, negative cytotoxic crossmatch (PFNC) or positive cytotoxic crossmatch (PCC), from 22 centers. Associations between DSA, graft loss and mortality after adjusting for PSR model factors were tested, using 9669 compatible patients as a comparison.
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Evaluation of the pediatric patient for liver transplantation:
2014 practice guideline by the AASLD, AST and the NASPGHAN

Hepatology
Current American Association for the Study of Liver Diseases (AASLD) liver transplant evaluation guidelines include both adult and pediatric patients. While pediatric liver transplants account for 7.8 percent of all liver transplants in the United States, sufficient differences between pediatric and adult patients seeking liver transplantation (LT) now require independent, yet complementary documents. This document will focus on pediatric issues at each level of the evaluation process.
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Excess mortality on the liver transplant waiting list: Unintended policy consequences and MELD Inflation
Hepatology
The model for end-stage liver disease (MELD) allocation system for liver transplantation provides "exceptions" for diseases such as hepatocellular carcinoma (HCC). It was the aim of this study to assess equipoise between exception candidates and non-exception candidates on the waiting list and to assess if the exception system contributes to steadily increasing regional MELD at transplant.
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Genetic variation in immunoglobulin gamma receptor affects survival after lung transplantation
American Journal of Transplantation (log in required)
Chronic rejection remains the most important complication after lung transplantation (LTx). There is mounting evidence that both rheumatoid arthritis and chronic rejection share similar inflammatory mechanisms. As genetic variants in the FCGR2A gene that encodes the immunoglobulin gamma receptor (IgGR) have been identified in rheumatoid arthritis, we investigated the relationship between a genetic variant in the IgGR gene and chronic rejection and mortality after LTx.
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Liver transplantation in recipients receiving renal replacement therapy: Outcomes analysis and the role of intraoperative hemodialysis
American Journal of Transplantation (log in required)
The Model for End-Stage Liver Disease (MELD) system has dramatically increased the number of recipients requiring pretransplant renal replacement therapy (RRT) prior to liver transplantation (LT). Factors affecting post-LT outcomes and the need for intraoperative RRT (IORRT) were analyzed in 500 consecutive recipients receiving pretransplant RRT, including comparisons among recipients not receiving IORRT, receiving planned IORRT, and receiving emergent, unplanned RRT after LT initiation.
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First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities
American Journal of Transplantation (log in required)
Since mid-March 2014, the frequency with which cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection have been reported has increased, with the majority of recent cases reported from Saudi Arabia and United Arab Emirates (UAE). In addition, the frequency with which travel-associated MERS cases have been reported and the number of countries that have reported them to the World Health Organization (WHO) have also increased. The first case of MERS in the United States, identified in a traveler recently returned from Saudi Arabia, was reported to CDC by the Indiana State Department of Health on May 1, 2014, and confirmed by CDC on May 2.
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Split liver transplantation using hemiliver graft in the MELD era: A single center experience in the United States
American Journal of Transplantation (log in required)
Under the "sickest first" Model for End-Stage Liver Disease (MELD) allocation, livers amenable to splitting are most often allocated to patients unsuitable for split liver transplantation (SLT). The researcher's experience with SLT using hemilivers was reviewed.
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Doctors more likely to register as organ donors compared to the general public
Medical Daily
Many people fear that if they are a registered organ donor then their doctor will not treat them to the best of their ability in the event of a life-threatening condition. It is estimated that less than 40 percent of the public are registered organ donors in most countries. A recent study published in JAMA has revealed that a significantly larger proportion of physicians in Canada are registered for organ and tissue donation compared to members of the general public.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Long-term risks for kidney donors (Kidney International)
An easily calculable and highly predictive risk index for postoperative renal failure
after heart transplantation
(The Journal of Thoracic and Cardiovascular Surgery)
Variation in access to the liver transplant waiting list in the United States (Transplantation)

Don't be left behind. Click here to see what else you missed.
 



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