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Transplantation community sets a goal for increasing organ transplants over the next 5 years
The Donation and Transplantation Community of Practice (DTCP) Strategic Planning Committee, comprising the community partner organizations listed below, and government participation from the Centers for Medicare and Medicaid Services (CMS) and the Health Resources and Services Administration (HRSA), has been meeting since September 2012 to develop a strategic plan for improving donation and transplantation practices across the nation. Most recently, this group of committed individuals and organizations identified and approved the following collective goal: To increase the number of transplants each year by 1,000 over the next 5 years.
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Education on demand at
Find the educational content you need quickly and easily on the reorganized education page of the AST website. Find archives of past webinars and journal clubs, along with links to guidelines, directories, and other resources
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Registration open for ASN Kidney Week and 'Early Program' on transplantation
In recent years, there have been important advances in the field of kidney transplantation that will impact the care of the kidney transplant recipient. ASN, in cooperation with AST, has developed a program providing an interactive, case-based overview of exciting advances in kidney transplantation, with a focus upon specific populations, complications, and ethical issues. Nephrologists with an interest in transplantation, transplant physicians, and trainees in the nephrology are encouraged to attend this program. Get full program details and register here.
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AST Pay it Forward Recruitment Campaign Winners
Congratulations to the 2014 Pay it Forward Member-Get-A-Member Campaign Winners! The following members encouraged their colleagues to join the AST and because of them, the AST community continues to grow:
  • Marian O'Rourke, RN, CCTC - Grand Prize: Apple iPad and complimentary membership dues for 2015
  • Peter Nguyen, M.D. - 2nd Prize: $500 AST Bucks
  • John Baddley, M.D., MSPH - 3rd Prize: $250 AST Bucks
Do you have a colleague who would enjoy all of the wonderful benefits of AST membership? Spread the word and encourage them to join! Click here for more information.

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Have you visited AST's Career Center?
Whether you are searching for a fellowship program to begin your career in transplantation, or are a seasoned transplant professional looking for a change, AST can help you! Visit our Career Center at to find your next exciting career opportunity!

Additionally, if you are looking to hire talented professionals for your transplant center, visit the Employer Portal to post your open positions. AST members receive a 75 percent discount on 90-day job postings. Please contact with any questions.

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AST congratulates the newest Board of Director members
AST is pleased to welcome Kenneth A. Newell, M.D., Ph.D., as the AST President! The results of the AST Board of Director elections were announced during the Town Hall during the WTC in San Francisco on July 29. AST congratulates the following newest board members: President-Elect: James S. Allan, M.D., MBA; Treasurer: Thomas Pearson, M.D., DPhil, and three new councilors-at-large: Sharon M. Bartosh, M.D., Richard Formica, M.D., and Josh Levitsky, M.D. Congratulations to all!
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.

Recognizing Excellence in Transplantation
The AST Achievement Awards recognize AST members who have made significant contributions to the field of transplantation as investigators, advocates, mentors, and more. The AST is delighted to recognize the following outstanding individuals:
  • AST Lifetime Achievement Award - J. Harold Helderman, M.D.
  • AST Lifetime Achievement Award - Susan J. Nelson, CAE
  • AST Senior Achievement Award in Clinical Transplantation - Jay A. Fishman, M.D.
  • AST Mentoring Award - Manikkam Suthanthiran, M.D.
  • AST Transplant Advocacy Award - Lois Capps
  • AST Clinician of Distinction Award - Ashley Vo, PharmD
  • AST Basic Science Established Investigator Award - David KC Cooper, M.D., Ph.D.
  • AST Clinical Science Established Investigator Award - Parmjeet Randhawa, MBBS
  • AST Basic Science Investigator Award - Gilles Benichou, M.D., Ph.D.
  • AST Clinical Science Investigator Award - Josh Levitsky, M.D.
  • AST Basic Science Career Development Award - Mandy Ford, Ph.D.
  • AST Clinical Science Career Development Award - Julie Ho, M.D.

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Advancing Transplantation Research
AST is proud to have a long history of supporting transplantation research. This year, the AST together with its corporate supporters, are awarding over $300,000 in research funding to support new and young investigators. AST congratulates the following recipients:
  • AST/Astellas Clinical Science Faculty Development Grant - Jayme Locke, M.D., MPH
  • AST/Astellas Basic Science Fellowship Grant - Pritha Sen, M.D.
  • AST/BMS Clinical Science Fellowship Grant - Aravind Cherukuri, M.D.
  • AST/Genentech Basic Science Fellowship Grant - Sergio Duarte, Ph.D.
  • AST/Novartis Clinical Science Fellowship Grant - Dmitry Rozenberg, M.D., FRCPC

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  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE


Now accepting abstracts
The Cutting Edge of Transplantation
Immunity and Inflammation: Engineering Cell, Gene, and Drug Therapies

Feb. 5-7, 2015
Sheraton Wild Horse Pass – Chandler, Arizona

Make plans to attend this high-energy, intimate meeting where expert clinicians, leading diagnosticians, and world class scientists will address the field’s cutting edge challenges together with an engaged audience. This year’s CEOT will feature sessions on:
  • A Critical Review of Cell Therapies
  • Whatever Happened to Gene Therapy?
  • Organ Repair and Regeneration, and Organ Generation
  • Drug Development and Rediscovering Pathways
Submit Your Basic, Clinical or Translational Abstract Here!

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Kidney transplantation in children
The New England Journal of Medicine
This review discusses unique aspects of kidney transplantation in children that necessitate specialized approaches and have resulted in clinical advances so that kidney transplantations in young children have higher success rates than in any other age group.
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Association between liver transplant center performance evaluations and transplant volume
American Journal of Transplantation
There has been increased oversight of transplant centers and stagnation in liver transplantation nationally in recent years. This study hypothesized that centers that received low performance (LP) evaluations were more likely to alter protocols, resulting in reduced rates of transplants and patients placed on the waiting list. They evaluated the association of LP evaluations and transplant activity among liver transplant centers in the United States using national Scientific Registry of Transplant Recipients data (January 2007 to July 2012). They also compared the average change in recipient and candidate volume and donor and patient characteristics based on whether the centers received LP evaluations.
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Circulating levels of 25-hydroxyvitamin D and acute cellular rejection in kidney allograft recipients
Vitamin D, in addition to its established role in bone metabolism, may regulate the immune system and affect the outcome of allografts. This study identified 351 kidney allograft recipients who had serum levels of 25-hydroxyvitamin D (25[OH]D) measured within the first 30 days of transplantation. They evaluated the relationship between the circulating levels of 25(OH)D and acute cellular rejection (ACR), cytomegalovirus (CMV) disease, BK virus nephropathy, and kidney graft function.
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The risk of recurrent IgA nephropathy in a steroid-free protocol and other modifying immunosuppression
Clinical Transplantation
Recurrent glomerulonephritis is an important cause of kidney allograft failure. The effect of immunosuppression on recurrent IgA nephropathy (IgAN) is unclear. This study analyzed the impact of steroids and other immunosuppression on the risk of recurrent IgAN post-kidney transplantation. Between June 1989 and November 2008, 3311 kidney transplants were performed at our center. IgAN was the primary disease in 124 patients; of these, 75 (60.5 percent) patients received steroid-based immunosuppression (15 undergoing late steroid withdrawal), and 49 (39.5 percent) were maintained on steroid-free immunosuppression.
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Azithromycin improves lung function in patients with post-lung transplant bronchiolitis obliterans syndrome: A meta-analysis
Clinical Transplantation
Azithromycin has been shown to reverse or halt the decline of forced expiratory volume in one s (FEV1) in patients with bronchiolitis obliterans (BOS) syndrome following lung transplant. The overall effect of azithromycin on the absolute values of FEV1 has not been compared between reported studies. The research team studied the effects of azithromycin on lung function in patients with post-lung transplant BOS syndrome.
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Prognostic implications of recipient or donor hepatitis B seropositivity in thoracic transplantation: analysis of 426 hepatitis B surface antigen-positive recipients
Transplant Infectious Diseases
Prognostic data on survival of hepatitis B surface antigen-positive (HBsAg+) recipients and of hepatitis B core antibody-positive (HBcAb+) donors are limited in the thoracic transplantation (TT) cohort. Improved understanding of risks could potentially expand the recipient and donor pools. Post-hoc analysis of limited-access dataset of the United Network for Organ Sharing database from January 2000–September 2010 was performed. Analyses were performed for all TT, including single and bilateral lung, orthotopic heart, and simultaneous heart-lung transplants. The primary analyzed outcome was overall survival. A Cox proportional multivariate hazards model was used to adjust for significant risk predictors.
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Missed last week's issue? See which articles your colleagues read most.

    Alemtuzumab-based induction treatment versus basiliximab-based induction treatment in kidney transplantation (the 3C Study): A randomized trial (The Lancet (log in required))
The policy of placing older donors into older recipients: Is it worth the risk? (Clinical Transplantation (log in required))
A randomized controlled trial of daclizumab versus anti-thymocyte globulin induction for heart transplantation (Transplantation Research)
Everolimus with low-dose tacrolimus in simultaneous pancreas and kidney transplantation (Clinical Transplantation (log in required))

Don't be left behind. Click here to see what else you missed.

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Colby Horton, Vice President of Publishing, 469.420.2601
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