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Pancreas transplantation from donors after circulatory death from the UK
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This study reports the comparative short-term results of pancreas transplantation from donors after circulatory death and pancreases from brainstem deceased donors. Between January 2006 and December 2010, 1009 pancreas transplants were performed in the United Kingdom, with 134 grafts from DCD and 875 from DBD. DCD grafts had no premortem pharmacological interventions performed. These results from donors with broader acceptance criteria in age, body mass index, premortem interventions, etc. suggest that DCD pancreas grafts may have a larger application potential than previously recognized. More



 SOCIETY NEWS


Save the date for AST's first Cutting Edge of Transplantation (CEOT) meeting
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"B Cells from Bedside to Bench to Bedside: A Comprehensive Look at B Cells and Antibodies in Transplantation," will be held Feb. 14-16, 2013 in Phoenix. AST's Cutting Edge of Transplantation (CEOT) meeting is a multi-expert view of the most important clinical and research problems in transplantation. Integrated clinical transplant and basic science talks define best approaches to management and research questions. The meeting has a clear focus on major clinical problems and the research needed to guide current and future therapies. Not a clinical meeting, not a research meeting — simply the cutting edge of both.

Abstract submission will open in late August. Clinical, basic and translational abstracts related to the meeting topic will be considered. Submit as many as you'd like!


Poll: What is your preferred method for receiving your membership dues notice?
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AST would like your feedback. We are considering offering members a paperless option for membership dues renewal notices. Please take our poll here.

Dr. Peter Reese receives 2011 Presidential Early Career Award for Scientists and Engineers
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AST member Dr. Peter Reese received the Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States Government to science and engineering professionals in the early stages of their independent research careers. Dr. Reese is an assistant professor of Medicine and Epidemiology at the Perelman School of Medicine at the University of Pennsylvania. Dr. Reese received the award on July 31 for "innovative work on ethical approaches to expanding access to organ transplantation."


Learn more about Dr. Reese's research.


The ESOT-AST Joint Meeting: Cutting edge science
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"Transformational Therapies and Diagnostics in Transplantation," will be held on Oct. 12-14 at Palais de la Méditerranée in Nice, France. ESOT and AST have partnered once again to present the best transplantation science. The international faculty will critically analyze important topics such as: The results of recent clinical trials using costimulation blockade, new challenges in the diagnosis and treatment of antibody mediated rejection, pharmacogenetic testing in patient management, new immunosuppressive agents in the pipeline, new interventions for delayed graft function and graft fibrosis and current immunosuppressive therapies and identify unfulfilled needs and potential new interventions.

Register by Sept. 21 to take advantage of the early registration discounted rates. Register online at www.a-s-t.org/events/astesot-joint-meeting. View the program and travel information here.











Endpoints for clinical trials in kidney transplantation public workshop
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The Food and Drug Administration will hold a public workshop in Silver Spring, Md., to discuss the endpoints for clinical trials of drugs and therapeutic biologics in kidney transplantation on Sept. 10, from 9 a.m. - 6 p.m., and on Sept. 11, from 8 a.m. - 3 p.m. The meeting will include a discussion of measure of patient and graft survival, evaluation of the allograft by histology and biomarkers, glomerular filtration rate or other measures of renal function, evaluation of safety and other topics. Input from this public workshop will help in developing topics for further discussion and may serve to inform recommendations on potential endpoints in clinical trials of kidney transplantation. Registration is free. Contact Christine Moser at 301-796-1300 or email endpoints@fda.hhs.gov. More information is available here.

 TRANSPLANT NEWS


Experimental pump keeps children alive to receive heart transplant
CBS News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There is new research on a remarkable medical device that helps children waiting for heart transplants. A recent study shows that the device can drastically improve a child's chance of survival. The device, called the Berlin Heart, takes over the heart's job of pumping blood. A tube implanted inside the heart channels blood to the pump, which sits outside the body. It then sends blood directly to arteries supplying the rest of the body.

Related articles:
Mechanical device helps kids waiting for transplant (U.S. News & World Report)
Unprecedented study shows Berlin Heart device provides life-saving 'bridge' for young children, babies (redOrbit.com)
More

Availability, utilization and outcomes of deceased diabetic donor kidneys; analysis based on the UNOS registry
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The number of kidneys obtained from deceased diabetic donors available for transplantation has increased more than eightfold in the past 15 years. Both overall and death-censored survival of organs from diabetic standard criteria donors was significantly better than that of organs obtained from nondiabetic ECD while inferior to that from nondiabetic standard criteria donors.

Related article:
Engineered pancreatic tissues could lead to better transplants for diabetics (Medical Xpress)
More

New research prints blood vessels from inkjet printer
ZDNet    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at the Fraunhofer Institute are working on a new technology: Blood vessels created with specialized inkjet printers. The potential for this technology is quite amazing. If doctors can "print" blood vessels, then they can direct the river of blood to locations that need blood. This is particularly valuable in transplants and may help save lives.

Related article:
The miraculous way scientists are growing organs in labs (Business Insider)
More

American Heart Association wants better cardiac evaluation of kidney transplant candidates
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The American Heart Association is trying to establish better standardization of cardiac evaluation practices in patients awaiting kidney transplants. More

Feds renew hand transplant researchers' support
The Associated Press via Georgia Public Broadcasting    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An Atlanta research partnership responsible for the South's first human hand transplant has secured a new $31 million federal grant to continue a coalition launched five years ago. The Clinical & Translational Science Institute is a partnership led by Emory University. It also includes other major healthcare and research players like Georgia Tech, Morehouse medical school, Grady Health System and the VA Medical Center.

Related article:
Atlanta research coalition gets $31 million (The Sacramento Bee)
More

A prospective study on living related kidney donors' quality of life in the first year: Choosing appropriate reference data
Clinical Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Prospective studies on living kidney donors' quality of life are still rare. Most existing studies compare healthy donors with the general population, including subjects with diseases. This is the first prospective study comparing living donors' QoL with reference data of both the general population and healthy individuals. The impact on physical QoL seems to persist for at least three months after kidney donation. It could be demonstrated that in the context of living donation, healthy individuals provide more adequate reference data. More
 



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