The independent living donor advocate
AST
Many in the transplantation community have questions about what the ILDA role entails and how to operationalize it. To clear up the confusion, I have invited Rebecca Hays, chair of the AST’s Live Donor Community of Practice (LDCOP) to blog about recent steps the AST has taken to address the role of the ILDA.
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AST Provides Comments to NIH on HOPE Act
AST
The AST has responded to the DHHS/NIH request for public comment on proposed "Human Immunodeficiency Virus (HIV) Organ Policy Equity (HOPE) Act Safeguards and Research Criteria for Transplantation of Organs Infected With HIV."
AST TIRN research grant request for proposals
AST
The AST Transplantation and Immunology Research Network (TIRN) research grants program supports fellows, junior faculty, and allied health professionals by funding innovative research in basic, clinical, and translational science. A limited number of grants will be awarded for research projects beginning July 1, 2016. The request for proposals is open now at www.TIRN.org/funding. Applications must be completed by 11:59 p.m. Pacific Standard Time on Sunday, Nov. 1, 2015. For more information, visit www.TIRN.org or email TIRN@myAST.org.
PRODUCT SHOWCASE
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You care about your transplant
patients. And so do we. That’s
why we’re introducing Astellas
Cares—a new program that
offers you customized tools,
educational resources, and
comprehensive support to help
your patients care for their
health. To register, visit
AstellasCares.com/Transplant
today.
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Education and Clinical Tools for the Independent Living Donor Advocate: Webinar Sept. 16
AST
"Basics of Informed Consent for Living Donors" is the next webinar in the Education and Clinical Tools for the Independent Living Donor Advocate (ILDA) webinar series, and takes place Wednesday, Sept. 16 at 1 p.m. EDT. The entire nine-webinar series developed by the AST Live Donor Community of Practice is free to AST members and their associates, just register with an AST member username and password at www.myAST.org/ILDA.
UPCOMING EVENTS IN TRANSPLANTATION
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Surrogate Endpoints for Clinical Trials in Kidney Transplantation Public Workshop
FDA
Sept. 28, 2015 | Arlington, VA
For more information: http://www.fda.gov/Drugs/NewsEvents/ucm449248.htm
ASHI 41st Annual Meeting
ASHI
Sept. 28 - Oct. 2, 2015 | Savannah, GA
For more information: http://www.ashi-hla.org/events/annual-meeting/
2015 Banff/CST Joint Meeting
CST
Oct. 5-10, 2015 | Vancouver
For more information: http://www.cst-transplant.ca/meetings_asm.html
Society for Transplant Social Workers
STSW
Oct. 7-9, 2015 | Columbus, OH
For more information: https://www.stsw.org/conference/
ASN Kidney Week
ASN
Nov. 3-8, 2015 | San Diego, CA
For more information: https://www.asn-online.org/education/kidneyweek/
AASLD Liver Week
AASLD
Nov. 13-17, 2015 | San Francisco, CA
For more information: http://www.aasld.org/events-professional-development/liver-meeting
Save the date: CEOT 2016 – Cutting Edge of Transplantation
AST
Feb. 25-27, 2016 | Phoenix, AZ
For more information: http://2016.ceot.myast.org/
PRODUCT SHOWCASE
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The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
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A multistep, consensus-based approach to organ allocation in liver transplantation: Toward a 'blended principle model'
American Journal of Transplantation
Since Italian liver allocation policy was last revised (in 2012), relevant critical issues and conceptual advances have emerged, calling for significant improvements. We report the results of a national consensus conference process, promoted by the Italian College of Liver Transplant Surgeons (for the Italian Society for Organ Transplantation) and the Italian Association for the Study of the Liver, to review the best indicators for orienting organ allocation policies based on principles of urgency, utility, and transplant benefit in the light of current scientific evidence.
Complement modulation of anti-aging factor Klotho in ischemia/reperfusion injury and delayed graft function
American Journal of Transplantation
Klotho is an anti-aging factor mainly produced by renal tubular epithelial cells (TEC) with pleiotropic functions. Klotho is down-regulated in acute kidney injury in native kidney; however, the modulation of Klotho in kidney transplantation has not been investigated. In a swine model of ischemia/reperfusion injury (IRI), we observed a remarkable reduction of renal Klotho by 24 h from IRI.
Cardiac response to early conversion from calcineurin inhibitor to everolimus in renal transplant recipients – a 3-year serial echocardiographic substudy of the randomized controlled CENTRAL trial
Clinical Transplantation
In transplant recipients, calcineurin inhibitors (CNIs) are associated with adverse cardiac effects while mTOR inhibitors have been reported to be beneficial. We performed a randomized controlled trial (RCT) in de novo renal transplant recipients examining cardiac responses of everolimus vs. CNI. This was a substudy of the three-yr CENTRAL study, an RCT on safety and efficacy of early (week 7 post-engraftment) conversion from cyclosporine A (CsA) to everolimus vs. continued CsA. Thirty-nine recipients [median age 64 year, (range 31–81)] completed echocardiographic evaluations at baseline, one, and three year.
PRODUCT SHOWCASE
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VTI’s disposable intraoperative Doppler probes are ready to verify technical results.
There’s no longer the need to perform sterilization that frequently causes irreversible damage to the traditional Doppler probes.
Advantages include fewer replacements of conventional Doppler probes damaged during sterilization, OR time saved, and a reduction in specialty procedures.
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A personalized follow-up of kidney transplant recipients using video conferencing based on a 1-year scoring system predictive of long term graft failure (TELEGRAFT study): Protocol for a randomized controlled trial
BMC Nephrology
Numerous well-established clinical parameters are taken into consideration for the follow-up adaptation of kidney transplant recipients, but there are important disparities between countries, centres and clinicians. Therefore, novel scoring systems have been developed, for instance the Kidney Transplant Failure Score (KTFS) which aims to stratify patients according to their risk of return to dialysis. We hypothesize that the efficiency of the follow-up after one year post-transplantation can be improved by adapting it to the risk of graft failure defined by the KTFS estimation.
High emergency lung transplantation: Dramatic decrease of waiting list death rate without relevant higher post-transplant mortality
Transplant International
Many candidates for lung transplantation (LT) die on the waiting list, raising the question of graft availability and strategy for organ allocation. We report the experience of the new organ allocation program, “High Emergency Lung Transplantation” (HELT), since its implementation in our center in 2007. Retrospective analysis of 201 lung transplant patients, of whom 37 received HELT from July 1, 2007 to May 31, 2012.
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