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Donor-derived fungal infections in organ transplant recipients: Guidelines of the American Society of Transplantation, Infectious Diseases Community of Practice
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Donor-derived fungal infections can be associated with serious complications in transplant recipients. Most cases of donor-derived candidiasis have occurred in kidney transplant recipients in whom contaminated preservation fluid is a commonly proposed source. Donors with cryptococcal disease, including those with unrecognized cryptococcal meningoencephalitis may transmit the infection with the allograft. This document discusses the characteristics, evaluation and approach to the management of donor-derived fungal infections in organ transplant recipients. More


Have REMS questions? AST has answers... in less than 15 minutes
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Visit AST's newly created Risk Evaluation and Mitigation Strategies (REMS) Resource Center to listen to a brand new podcast; a conversation between Dr. Richard Formica (Yale University) and Steven Gabardi, PharmD (Harvard Medical School). Drs. Formica and Gabardi address questions important to all transplant professionals dealing with REMS, and provide a follow up to the December 2010 REMS podcast. The resource center will be updated in the coming weeks and months to provide you with the tools you need to address issues involving REMS.

ESOT-AST Joint Meeting: Transformational Therapies and Diagnostics in Transplantation
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The ESOT-AST Joint Meeting is less than a month away, but there is still time to register at discounted rates. Register by Friday, Sept. 21 to save; register and view the program on the ESOT website, in the "Meetings" section. Faculty and attendees will critically analyze important topics such as the results of recent clinical trials using costimulation blockade, new challenges in the diagnosis and treatment of antibody mediated rejection, pharmacogenetic testing in patient management, new immunosuppressive agents in the pipeline, new interventions for delayed graft function and graft fibrosis and current immunosuppressive therapies and identify unfulfilled needs and potential new interventions. Transformational Therapies and Diagnostics in Transplantation will be held on Oct. 12-14 at Palais de la Méditerranée in Nice, France.

AST awards program: Nominate your colleagues
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AST is also soliciting nominations for AST Achievement Awards. The deadline for submissions is Nov. 19. AST sponsors a variety of achievement awards according to faculty rank in recognition of the AST members' achievements and contributions to the field of transplantation. AST members are encouraged to nominate deserving candidates for consideration. For complete information on awards eligibility criteria, application requirements, the review process and to submit a nomination, please visit the awards section of the AST website.

AST grants program: Submit an application for funding
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The American Society of Transplantation (AST) is now accepting applications for AST faculty and fellowship grants. The deadline for submissions is Nov. 19, 2012. AST grants support a wide range of basic and clinical research topics. AST members should bring this program to the attention of their colleagues in the field of transplantation at their institutions and support their applications. For complete information on grants eligibility criteria, application requirements, funding guidelines, the review process and to submit an application, please visit the grants section of the AST website.


Texas woman to receive first US double arm transplant
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A Texas woman who lost all four limbs to a flesh-eating bacteria has been approved for a double arm transplant at Boston's Brigham and Women's Hospital in what will be the first such procedure performed in the United States. Katy Hayes, 44, of Kingwood, Texas, will receive two new arms above the elbow. The hospital is working with a regional organ donor bank to find a donor. The surgery has not yet been scheduled.

Related articles:
Texas mom gets go-ahead for historic double-arm transplant (NBC)
Double arm transplant 'pioneer' tells her story (WBUR-FM)
For amputee, ring a symbol of what future holds (The Houston Chronicle)

Womb transplant surgeries offer hope
The Sydney Morning Herald    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Two women have been given hope of having children after surgeons in Sweden performed the world's first mother-to-daughter uterus transplants. In what was described as an exciting breakthrough, the two unnamed Swedish women, both in their 30s, received wombs from their mothers. A team of more than 10 surgeons from the University of Gothenburg completed the pioneering procedure without complications following several years of training.

Related articles:
Swedish Doctors Perform First Mother-Daughter Uterus Transplant (RedOrbit)
Doctors perform world's first uterus transplant between a mother and her daughter (The Mail Online)

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Novel program cuts CMV-related admissions in transplant patients
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Danish researchers have developed a new program that could help dramatically lower rates of hospital admissions due to cytomegalovirus (CMV) infection among recipients of solid organ transplants (SOT). "We were able to identify a number of processes which potentially could be optimized in a systematic way in order to diagnose the infection at an earlier stage, before it causes clinical disease and where it is easier to manage," said lead investigator, Dr. Caspar da Cunha-Bang, an attending physician at the University of Copenhagen. More

Roberts boosts visibility of bone marrow transplants
USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
As ABC's Good Morning America anchor Robin Roberts prepares for a bone marrow transplant, advocates in the transplant community are praising her efforts to raise awareness about the lifesaving procedure and increase the number of donors. In June, the morning show host announced that she would undergo a bone marrow transplant to treat a rare blood disorder, myelodysplastic syndrome or MDS, that had damaged her marrow. More

Etiologies, risk factors, and outcomes of bacterial pneumonia after living donor liver transplantation
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The prevalence and clinical characteristics of bacterial pneumonia after living donor liver transplantation (LDLT) have not yet been elucidated. Researchers performed a retrospective analysis of 346 LDLT recipients. Fifty patients (14.5 percent) experienced bacterial pneumonia after LDLT, and they had a higher short-term mortality rate (42 percent) than patients with other types of bacterial infections after LDLT. Gram-negative bacteria accounted for 84 percent of the causative pathogens. More

Athena Diagnostics

Genetic testing can be a cost-effective way to increase the number of living related donor transplants. Mutational analysis may help direct long-term treatment plans, including pre-operative screening of potential kidney transplant recipients and living related donors.

Nearly half of kidney recipients in live donor transplant chains are minorities
Science Codex    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The largest U.S. multicenter study of living kidney transplant donor chains showed that 46 percent of recipients are minorities, a finding that allays previous fears that these groups would be disadvantaged by expansion of the donor pool through this type of exchange process. The study of a series of chain transplantations performed from February 2008 to June 2011 at 57 centers nationwide included 272 kidney transplants that paired organ donors who were incompatible with their relatives with strangers providing organs for altruistic reasons or with others donating an organ to an unknown patient because they were not a match for their own relatives. More

COPD raises dialysis patient death risk
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chronic obstructive pulmonary disease in patients starting dialysis increases their mortality risk and decreases their likelihood of receiving a kidney transplant, especially in current smokers, according to researchers. More

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