AST TIRN research grant request for proposals – due Nov. 1, 2015
The AST Transplantation and Immunology Research Network (TIRN) research grants program funds innovative research in basic, clinical, and translational science. A limited number of grants will be awarded for research projects beginning July 1, 2016. The request for proposals is open now at www.TIRN.org/funding.
AST/AJT Journal Club: Sept. 22
Join us for this free journal club discussion, hosted by AST's Transplant Regenerative Medicine and Thoracic and Critical Care Communities of Practice. We will be going over the article "Lung transplantation with donation after circulatory determination of death donors and the impact of ex vivo lung perfusion" from the April 2015 AJT. Visit the AST website for more information: http://www.myast.org/content/astajt-journal-club.
AST/AJT Journal Club Update
AST members: Did you know that you can plan a journal club on behalf of your community of practice (COP)? To give AST members the ability to discuss timely research as it emerges, the AJT can provide early access to upcoming articles so that AST members can plan and host journal clubs as these articles publish.
If you are interested in holding a journal club on behalf of your COP, please contact the chair or co-chair of your COP to discuss the guidelines.
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Education and Clinical Tools for the ILDA: Webinar Oct. 21
"Navigating the ILDA Role: Challenges and Responsibilities" is the next webinar in the Education and Clinical Tools for the Independent Living Donor Advocate (ILDA) webinar series, and takes place Wednesday, Oct. 21 at 1 p.m. EDT. The entire nine-webinar series, developed by the AST Live Donor Community of Practice, is free to AST members and their associates: just register with an AST member username and password at www.myAST.org/ILDA.
The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
UPCOMING EVENTS IN TRANSPLANTATION
2015 Banff/CST Joint Meeting
Oct. 5-10, 2015 | Vancouver
For more information: http://www.cst-transplant.ca/meetings_asm.html
Transplant Quality Institute
Oct. 7-9, 2015 | Dallas, TX
For more information: http://www.amfdt.org/
Society for Transplant Social Workers
Oct. 7-9, 2015 | Columbus, OH
For more information: https://www.stsw.org/conference/
ASN Kidney Week
Nov. 3-8, 2015 | San Diego, CA
For more information: https://www.asn-online.org/education/kidneyweek/
AASLD Liver Week
Nov. 13-17, 2015 | San Francisco, CA
For more information: http://www.aasld.org/events-professional-development/liver-meeting
CEOT 2016 – Cutting Edge of Transplantation
Feb. 25-27, 2016 | Phoenix, AZ
For more information: http://2016.ceot.myast.org/
Preimplant normothermic liver perfusion of a suboptimal liver donated after circulatory death
American Journal of Transplantation
Livers retrieved after circulatory death are associated with an increased incidence of primary nonfunction, early allograft dysfunction, and biliary strictures. The authors report a case of preimplant normothermic perfusion of a suboptimal liver from a 57-year-old donor after circulatory death who had been hospitalized for 9 days; predonation alanine transaminase level was 63 IU/L, and the period from withdrawal of life-supporting treatment to circulatory arrest was 150 minutes.
MicroRNA-144 dysregulates the transforming growth factor-Î² signaling cascade and contributes to the development of bronchiolitis obliterans syndrome after human lung transplantation
The Journal of Heart and Lung Transplantation
Bronchiolitis obliterans syndrome (BOS), chronic lung allograft rejection, remains an impediment for the function of the transplanted organ. In this study, we defined the role of the microRNA (miRNA) miR-144 in fibroproliferation leading to BOS.
VTI’s disposable intraoperative Doppler probes are ready to verify technical results.
There’s no longer the need to perform sterilization that frequently causes irreversible damage to the traditional Doppler probes.
Advantages include fewer replacements of conventional Doppler probes damaged during sterilization, OR time saved, and a reduction in specialty procedures.
A reassessment of the survival advantage of simultaneous kidney-pancreas versus kidney-alone transplantation
Simultaneous kidney and pancreas (SPK) transplantation is an attractive option for end-stage renal disease patients with type 1 diabetes. Although SPK transplantation is superior to remaining on dialysis, the survival advantage for SPK recipients compared to kidney transplantation alone (KTA) is controversial.
Desirability and feasibility of wireless electronic monitoring of medications in clinical trials
Translational Behavioral Medicine
Medication nonadherence is a vexing problem in health care necessitating patients and health professionals’ efforts to prevent, minimize, or reverse it. Research participants’ inconsistent medication taking obscures treatment efficacy and adds costs to biomedical research. Electronic monitoring devices (EMDs), like the Medication Event Monitoring System (MEMS), have grown in sophistication, providing precise, timely insights into individuals’ medication-taking patterns across clinical populations. This article reports on the desirability and feasibility study of using a wireless EMD in clinical research to promote adherence to clinical regimens and research protocols.
Chest wall, thymus, and heart vascularized composite allograft proof of concept cadaveric model for heart transplantation
Annals of Plastic Surgery
The use of vascularized composite allografts allows for the reconstruction of complex scenarios that previously have required multistaged operations. Heart transplantation often follows a series of previous operations leading to chest wall deformities and significant mediastinal adhesions that can limit the use of larger hearts, making it difficult to find a suitable donor.