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Single-lung transplantation can be performed with acceptable outcomes using selected donors with heavy smoking history
The Journal of Heart and Lung Transplantation
It was attempted to determine if adult, single-lung transplantation could be performed with acceptable results in heavy-smoking donors. Although single-lung transplantation with actively smoking HSDs results in worse results, outcomes are acceptable and should continue to be considered.
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SOCIETY NEWS


Register now for the T3 Live Webinar series: Starting Oct. 15
Webinars for the Timely Topics in Transplantation series will be broadcast live every month from Oct. 2013 - April 2014. Each webinar is held on a Tuesday at 2 p.m. EST. Preregistration is required for each webinar and is free for AST members — just use your AST username and password during registration! Nonmembers may purchase access to any of the webinar for a fee of $25 each.
Upcoming Webinars:
  • Tuesday, Oct. 15: Banff Conference on Allograft Pathology: 2013 Summary
  • Tuesday, Oct. 22: Update on the AST ID Guidelines Third Edition and the CMV Consensus Document
  • Tuesday, Nov. 19: International Pancreas and Islet Transplant Association World Congress: 2013 Summary
  • Tuesday, Dec. 17: Adherence Tools of Today and Tomorrow: Improving Adherence in the Challenging Transplant Patient
  • Tuesday, Jan. 21, 2014: Update on Kidney Allocation
  • Tuesday, Feb. 18, 2014: Complying with New UNOS Living Donor Care Policies
  • Tuesday, March 18, 2014: Hepatitis C Eradication: Liver Transplant Patients and Beyond
  • April 2014: Role of Pre-transplant HLA Testing/Desensitization in Solid Organ Transplantation

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Submit abstracts for AST's Cutting Edge of Transplantation 2014
AST presents the Cutting Edge of Transplantation Feb. 13-15, at the Sheraton Wild Horse Pass in Chandler, Ariz. Submit your basic, clinical or translational abstract related to the CEOT 2014 meeting topic: "Optimizing Long-term Transplant Survival: Therapeutics, Targets, Technologies." Abstracts will be presented in mini-oral and/or poster format. All abstracts presented at CEOT will receive focused attention and constructive feedback from attendees and faculty. View the preliminary program now to see what will be covered, and check back often as expert faculty are being announced soon. Registration opens in October — don't miss your chance to secure a place at the limited attendance meeting.
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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


TRANSPLANT NEWS


Tissue Doppler imaging for rejection surveillance in pediatric heart transplant recipients
THe Journal of Heart and Lung Transplantation
Most transplant centers perform serial cardiac biopsies for rejection surveillance in pediatric heart transplant recipients. Biopsy specimen-proven rejection is associated with a significant decline in biventricular TDI velocities from baseline in pediatric HT recipients. By using well-defined TDI criteria to predict non-rejection, a substantial proportion of planned biopsies may be deferred or avoided at minimal risk to pediatric HT recipients.
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Clostridium difficile infection increases mortality risk in lung transplant recipients
The Journal of Heart and Lung Transplantation
Clostridium difficile infection and associated mortality in solid organ transplant recipients is rising, but data are scarce in lung transplant recipients. CDI rates varied widely from 2000 through 2011, with the highest rates in 2007 to 2008. Lung transplant recipients who developed CDI had a higher risk of death, especially when CDI occurred in the first 6 months after transplant.
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Impact of extracorporeal membrane oxygenation or mechanical ventilation as bridge to combined heart-lung transplantation on short-term and long-term survival
Transplantation
Extracorporeal membrane oxygenation and mechanical ventilation can be used as a bridge to heart-lung transplantation. The goal of this study was to determine if pretransplantation ECMO or MV affects survival in HLT.
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Increased recipient body mass index is associated with acute rejection and other adverse outcomes after kidney transplantation
Transplantation
Outcomes of kidney transplant recipients with increased body mass index remain controversial. Increased BMI at kidney transplantation is a predictor of adverse outcomes, including BPAR. The role of pretransplantation weight reduction in improving graft and patient outcomes requires further study.
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Defining delayed graft function after renal transplantation: Simplest is best
Transplantation
Delayed graft function after renal transplantation can be diagnosed according to several different definitions, complicating comparison between studies that use DGF as an endpoint. This is a particular problem after transplantation with kidneys from donation after circulatory death kidneys, because DGF is common and its relationship to early graft failure may differ depending on the definition of DGF.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Cancer risk after ABO-incompatible living-donor kidney transplantation (Transplantation)
Preformed class II donor-specific antibodies are associated with an increased risk of early rejection after liver transplantation (Liver Transplantation)
Granulocyte colony-stimulating factor therapy: Reduced incidence of acute rejection episodes, allograft vasculopathy in heart transplant recipients (Transplantation Proceedings)
Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival (Liver International)
Will China's organ transplant reforms really work? (The Atlantic)

Don't be left behind. Click here to see what else you missed.


Alemtuzumab induction in renal transplantation permits safe steroid avoidance with tacrolimus monotherapy: A randomized controlled trial
Transplantation
The use of alemtuzumab as induction immunosuppression for renal transplantation introduces the possibility of long-term tacrolimus monotherapy, avoiding maintenance with both corticosteroids and mycophenolate mofetil.
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