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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Oct. 4, 2013


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SOCIETY NEWS


AST Public Policy Committee members deliver key messages directly to Decision-Makers on Capitol Hill
AST
On Sept. 24-25, AST's Public Policy Committee descended on Capitol Hill and met with more than a dozen Members of Congress in the U.S. Senate and House of Representatives. A majority of the meetings were with the actual Senators and Congressmen themselves.

The two primary purposes for AST's visits with members of Congress was to: garner further support for federal funding of NIH and medical research; as well as strengthen support and cosponsors for the Transplant Patient Immunosuppressive Drug Coverage for Kidney Patients Act of 2013. Read more here.

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It's time to renew your membership!
AST
To continue receiving all of the benefits AST membership has to offer in 2014, login to the AST website now to pay your dues. If you have forgotten your login credentials, simply click "Forgot Password" to have the information emailed to you. Contact the AST office at info@myAST.org with any questions. Members will receive a hard-copy invoice via regular mail in the near future.
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Register now for the T3 live webinar series: Starting Oct. 15
AST
Webinars for the Timely Topics in Transplantation series will be broadcast live every month from October 2013 - April 2014. Each webinar is held on a Tuesday at 2 p.m. EST. Pre-registration is required for each webinar and is free for AST members — just use your AST username and password during registration! Non-members may purchase access to any of the webinar for a fee of $25 each.
    Upcoming webinars:
  • Tuesday, Oct.15: Banff Conference on Allograft Pathology: 2013 Summary
  • Tuesday, Oct. 22: Update on the AST ID Guidelines Third Edition and the CMV Consensus Document
  • Tuesday, Nov. 19: International Pancreas and Islet Transplant Association World Congress: 2013 Summary
  • Tuesday, Dec. 17: Adherence Tools of Today and Tomorrow: Improving Adherence in the Challenging Transplant Patient
  • Tuesday, Jan.21, 2014: Update on Kidney Allocation
  • Tuesday, Feb. 18, 2014: Complying with New UNOS Living Donor Care Policies
  • Tuesday, March 18, 2014: Hepatitis C Eradication: Liver Transplant Patients and Beyond
  • April 2014: Role of Pre-transplant HLA Testing/Desensitization in Solid Organ Transplantation

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PRODUCT SHOWCASE
  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
 


Submit abstracts for AST's Cutting Edge of Transplantation 2014
AST
AST presents the Cutting Edge of Transplantation Feb. 13-15, 2014, at the Sheraton Wild Horse Pass in Chandler, AZ. Submit your basic, clinical or translational abstract related to the CEOT 2014 meeting topic: "Optimizing Long-Term Transplant Survival: Therapeutics, Targets, Technologies." Abstracts will be presented in mini-oral and/or poster format. All abstracts presented at CEOT will receive focused attention and constructive feedback from attendees and faculty. View the preliminary program now to see what will be covered, and check back often as expert faculty are being announced soon. Registration opens in October — don't miss your chance to secure a place at the limited attendance meeting.
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TRANSPLANT NEWS


Analysis: Expedited liver allocation in the United States
Liver Transplantation (login required)
The fate of donor livers allocated via an out-of-sequence expedited placement (EP) pathway has not been previously examined. It has been determined that the originating and receiving United Network for Organ Sharing (UNOS) regions of all donor livers procured between Jan. 1, 2010 and Oct. 31, 2012 and placed out of sequence with UNOS bypass code 863 (EP attempt) or 898 (miscellaneous). In this analysis, researchers reviewed the early function of these liver grafts and assessed the effect of EP allocation on wait-listed patients.
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Size matters in lung transplants — and bigger is better
By Joy Burgess
Previously, lung transplant experts have worked hard to match donor lung size close to the lung size of the transplant recipient. Physicians pursued size-matching due to the concern that lungs that were too large or too small could lead to potential problems, such as poor lung function, after transplantation. However, new transplant research is shattering that theory. New studies from Johns Hopkins Medicine and the University of Iowa show that choosing bigger lungs for patients is associated with better survival rates after transplantation.
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Shutdown: Tickets canceled, research stalled
MedPage Today
At the European Committee for Treatment and Research in Multiple Sclerosis meeting in Copenhagen, MedPage Today was told that at least one NIH researcher had been ordered to return to the U.S. because of the shutdown. ECTRIMS Secretary David Miller, MD, of University College in London, said the unnamed researcher had already arrived in Copenhagen but was told by NIH that he would have to go back home. "The most powerful country in the world," Miller said, shaking his head. The story was the same in Boston at the Regulatory Affairs Professionals Society (RAPS) conference where several FDA officials received orders to return to Washington, despite having already booked hotel rooms and travel arrangements. However, representatives of some regulatory agencies stayed to give presentations to the audience of regulatory professionals.
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Pretransplant donor-specific anti-HLA antibodies as predictors of early allograft rejection in ABO-compatible liver transplantation
Liver Transplantation (login required)
The significance of preexisting donor-specific HLA antibodies (HLA-DSAs) for liver allograft function is unclear. Previous studies have shown that humoral alloreactivity frequently accompanies acute cellular rejection (ACR). In the present study, researchers set out to determine whether pretransplant HLA-DSAs correlate with clinically significant ACR in the first 90 days after transplantation and, if so, to determine their predictive values.
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Analysis: Post-transplant lymphoproliferative disorder after pancreas transplantation
Clinical Transplantation (login required)
There are not a great deal of data on post-transplant lymphoproliferative disorder (PTLD) following pancreas transplantation. Researchers analyzed the United Network for Organ Sharing national database of pancreas transplants to identify predictors of PTLD development.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Clostridium difficile infection increases mortality risk in lung transplant recipients (The Journal of Heart and Lung Transplantation)
Increased recipient body mass index is associated with acute rejection and other adverse outcomes after kidney transplantation (Transplantation)
Alemtuzumab induction in renal transplantation permits safe steroid avoidance with tacrolimus monotherapy: A randomized controlled trial (Transplantation)

Don't be left behind. Click here to see what else you missed.


Donor risk prediction: How 'extended' is safe?
Current Opinion in Organ Transplantation (login required)
This article reviews recent developments in the selection of the lung donor that aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation resulting in long waiting times and significant mortality for those patients awaiting transplantation.
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Laboratory-based scoring system for prediction of hepatic inflammatory activity in patients with autoimmune hepatitis
Liver International (login required)
In autoimmune hepatitis (AIH), inflammation is closely related to fibrosis. Although transaminase levels are commonly used to assess hepatic inflammation, they may not relate directly to the histology. A noninvasive diagnostic score has been developed as an alternative to liver biopsy to help optimize treatment for AIH and monitor disease progress.
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