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The AST just launched a brand new Clinical Trials page. Check out our partner's current clinical trials. READ MORE
We just launched the 2019 COP giving contest: The Donation Derby. Watch this race, as the COPs compete for two prizes and fundraise for their upcoming initiatives. All donations made by COP members until the end of the year will count toward this contest, so be sure to check it out today.
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The AST is now accepting nominations for its 2020 Board of Directors. If you are interested in joining the AST Board, or know someone who is, we encourage you to submit your nomination. Learn more about the election process here.
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Veloxis Pharmaceuticals
Now you can see the different ways that different formulations are released and absorbed in the gastrointestinal system. You’ll also have the opportunity to explore comparative pharmacokinetic results in rapid metabolizers, efficacy data over 2 years, and safety information.
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Join us for an interactive discussion on organ allocation at the 2020 Cutting Edge of Transplantation (CEoT) meeting in Phoenix, AZ. Early bird registration is now open.
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Know someone in need of a college scholarship? The American Society of Transplantation is seeking creative content that helps raise awareness in specific areas of transplantation for its Power2Save initiative.
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Veloxis Pharmaceuticals
Immunosuppressive medications can be a financial burden for kidney transplant patients, potentially costing as much as $10,000 to $14,000 a year. These expenses can have a negative impact on patients’ lives and may play a role in medication nonadherence, which is associated with transplant failure. Learn more about support that is available with a free 30-day trial to allow your patients to start immediately at no cost. And, for patients who are eligible with commercial insurance coverage, a $0 co-pay card offers significant savings.
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The Women's Health COP (WHCOP) often receives requests for recommended conference speakers and content experts for educational projects such as webinars. To identify and highlight members throughout our society, we are creating a Women Speakers List of AST members and their areas of expertise. Submit Nomination
The Transplant Nephrology Core Curriculum (TNCC) is an online program jointly provided by the American Society of Nephrology and the American Society of Transplantation. The TNCC focuses on key information needed to prepare for the American Board of Internal Medicine Nephrology Board Certification and Maintenance of Certification examinations.
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| Upcoming Education Events
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Impact of estimation versus direct measurement of predonation glomerular filtration rate on the eligibility of potential living kidney donors
November 21, 2019 | 3 pm ET | Online Activity
For more information, click here
Efficacy and safety of bleselumab in kidney transplant recipients: A phase 2, randomized, open-label, noninferiority study
December 3, 2019 | 2 pm ET | Online Activity
For more information, click here
Visit the AST Member Spotlight page to read about how Nicole McCormick came to transplantation.
Interested in being featured in the AST Member Spotlight? Please contact rpaulin@myast.org for more information
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AJT
Solid organ transplant recipients are at risk for potentially life‐threatening infections due to lifelong immunosuppression. Vaccine‐preventable infections result in graft injury, morbidity, mortality and significantly increased medical costs. Unfortunately, the majority of transplant recipients continue to be underimmunized at the time of transplant and thereafter.
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AJT
Diagnosing lung transplant rejection currently depends on histologic assessment of transbronchial biopsies (TBB) with limited reproducibility and considerable risk of complications. Mucosal biopsies are safer but not histologically interpretable. Microarray‐based diagnostic systems for TBBs and other transplants suggest such systems could assess mucosal biopsies as well. We studied 243 mucosal biopsies from the third bronchial bifurcation (3BMBs) collected from seven centers and classified them using unsupervised machine learning algorithms.
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KidneyCare combines clinically validated AlloSure testing with AlloMap kidney and iBox to deliver personalized and Prognostic solutions for transplant patients.
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TruGraf® - The 1st and only non-invasive test to rule out “silent" subclinical rejection in stable kidney transplant recipients
The only test to be reimbursed as an alternative to surveillance biopsies
Developed by Clinicians for Clinicians
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AJT
Donation after Circulatory Death (DCD) is an alternative to Donation after Brain death (DBD), and is a growing strategy for organ procurement in the United States. The purpose of this analysis was to review the number and quality of hearts in one United Network for Organ Sharing (UNOS) Region that were not utilized as a potential consequence of nonheart DCD donation.
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Clinical Transplantation
Anticoagulation in heart transplant (HT) recipients increases the risk of hemorrhagic complications, so correct reversal of anticoagulation is needed. Dabigatran, a direct thrombin inhibitor is increasingly used for anticoagulation in patients with non‐valvular atrial fibrillation (NVAF) whose effect can be reversed by idarucizumab. Aim: to present a nationwide experience using idarucizumab for the urgent reversal of dabigatran before HT.
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Decades of clinical evidence has shown that HLA-specific antibodies may lead to hyperacute antibody-mediated rejection (ABMR).
Today, ABMR remains a major challenge to successful transplantation, but detection of donor specific antibodies (DSA) is the best tool for stratifying risk. LABScreen Single Antigen Beads remain the worldwide leader for the detection of DSA.
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JACC
In the contemporary era, nearly 85% of children with congenital heart disease will reach adulthood. Despite optimal medical and surgical treatment, many will experience a progressive decline in cardiopulmonary function leading to advanced heart failure. These patients present unique anatomic and physiological challenges to the care team, and unlike adults with acquired heart disease who progress to severe heart failure, advanced treatment options such as mechanical circulatory support and cardiac transplant may be limited.
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