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Save 50 percent on Cutting Edge of Transplantation registration until Nov. 30
AST
Register for the Cutting Edge of Transplantation 2014 by Nov. 30 and save 50 percent on regular registration rates — a doctoral AST member can attend for just $150! Don't miss the cutting edge program and the chance to engage in conversations with colleagues throughout this intimately-sized meeting.
If you have important research that affects graft survival (in the broadest sense possible), we want to hear about it at CEOT 2014. Submit your abstracts by Nov. 30 to be considered. You may even qualify for a $500 Young Innovator Award travel grant.
This activity is jointly sponsored by Global Education Group and the American Society of Transplantation. Continuing education credit will be offered for physicians, nurses, pharmacists, and transplant coordinators. Click here for full credit details. For information about accreditation of this program, please contact Global at 303-395-1782 or inquire@globaleducationgroup.com.
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Congress passes HIV organ policy equity act (HOPE Act)
AST
The American Society of Transplantation (AST), representing the majority of professionals engaged in the field of organ transplantation, applauded yesterday's action by the U.S. House of Representatives to bring the HIV Organ Policy Equity Act (HOPE Act) one step closer to being signed into law. The legislation, which has bipartisan support, has now passed in both the House of Representatives and Senate and will be sent to the president for final signature into law.
PRODUCT SHOWCASE
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The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
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Free live webinars Nov. 19 and Dec. 5, on demand webinars available 24/7
AST
Nov. 19 at 2 p.m. EST: IPITA World Congress 2013 Highlights presented by Dr. Peter Stock, Ph.D., Congress Chair (pre-registration is required).
Dec. 5 at 1 p.m. EST: Ethics in Transplantation by Dr. Yolanda Becker, part of the Fellows Live Webinar Series (pre-registration is required).
On Demand: View archived versions of the October webinars in the Timely Topics in Transplantation series. Banff Conference 2013 Highlights and Update on ID and CMV Consensus Guidelines are available for viewing at your convenience.
All webinars are free for AST members, Timely Topics in Transplantation webinars are $25 each for non-members. There are live webinars in both the Timely Topics in Transplantation and Fellows Live Webinar Series through May of 2014!
KDIGO releases new guideline for lipid management in CKD
AST
KDIGO has announced the publication of a new evidence-based Clinical Practice Guideline making recommendations on treatment of dyslipidemia in chronic kidney disease (CKD). KDIGO Co-Chair, Dr. Bertram Kasiske of the University of Minnesota, said, "Control of cholesterol and other lipid factors is very important for all our patients. This guideline is truly groundbreaking in its recommendations for putting and keeping CKD patients on lipid lowering medications." Read the complete story and download the new guideline here.
AST research grant applications and achievement awards nominations due on Dec. 16
AST
Applications for 2014 AST research grants and 2014 AST achievement awards are due on Monday, Dec. 16. Click here for funding eligibility requirements, or start an application. To submit a nomination for an AST Achievement award, click here.
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For nearly 30 years, physicians have trusted Viracor-IBT Laboratories to provide accelerated results, specialized expertise and exceptional service in transplant testing. Learn more at www.viracoribt.com.
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.
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Predictors of cancer risk in the long-term solid-organ transplant recipient
NCBI
Malignancy is increasingly the leading cause of mortality in solid-organ recipients. Cancer incidence among the transplant population is overall threefold to fivefold higher than the general population with poorer outcomes for late-stage disease. Insights into the identification of patients at particular risk of developing a posttransplantation malignancy are imperative to ensure appropriate measures are instigated to reduce associated morbidity and mortality. This review focuses on potential clinical, immunologic and genetic translational markers aimed at identifying long-term solid-organ transplant patients at high risk of developing cancer.
PRODUCT SHOWCASE
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Astellas is entering its 20th year focusing on transplant immunology. Today we remain steadfast in our commitment to advancing the field. Tomorrow we will seek new possibilities to help improve the transplant experience. Together. Please visit astellas.us
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Missed last week's issue? See which articles your colleagues read most.
Healthy brains impacting organ donation — but why?
By Denise A. Valenti
 Brain death occurs when there is a total and irreversible loss of all the brain's functions. Organ donation most commonly occurs when there is a brain death. Dr. Andreas Kramer and colleagues at the University of Calgary, Alberta, recently published a study investigating changes in the availability of donated organ tissue over the last decade. The rate of organ donation is in decline as the rate of neurologic death in brain trauma has dramatically reduced. But to what can we attribute the improved outcomes in these brain trauma cases?
Donor risk prediction: how 'extended' is safe?
Current Opinion in Organ Transplantation (login required)
This article reviews recent developments in the selection of the lung donor that aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation resulting in long waiting times and significant mortality for those patients awaiting transplantation.
Diabetes hikes infection-related death risk posttransplant
Renal & Urology News
Diabetes mellitus is an independent risk factor for infection-related death after kidney transplantation, data presented at the American Society of Nephrology's Kidney Week 2013 meeting show.
Manvir Kaur Hayer, MBChB, and collaborators at the Renal Institute of Birmingham, Queen Elizabeth Hospital, Birmingham, U.K., analyzed data from 19,103 kidney transplant recipients, of whom 2,968 had diabetes mellitus at the time of transplantation. Following transplantation, 2,085 patients died; 433 of the deaths were due to infection. The risk for death from any cause after transplantation was significantly higher for diabetics than non-diabetics, as was the risk for infection-related death.
Peritransplant lymphopenia Is a novel prognostic factor in recurrence of hepatocellular carcinoma after liver transplantation
Transplantation (login required)
Absolute lymphocyte count (ALC) is considered a surrogate marker for the level of immunosuppression and nutritional status of patients and a prognostic factor for survival and recurrence in several cancers. The aim of this study was to investigate the prognostic value of peritransplant ALC for the recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT).
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