This message contains images. If you don't see images, click here to view. Click here to advertise in this news brief. Mobile version  RSS  Subscribe  Unsubscribe  Archive  Media Kit Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Dec. 6, 2012   Targeting cells causing split tolerance allows fully allogeneic islet survival with minimal conditioning in NOD mixed chimeras American Journal of Transplantation (subscription required)    Share    Donor-specific tolerance induced by mixed chimerism is one approach that may eliminate the need for long-term immunosuppressive therapy, while preventing chronic rejection of an islet transplant. However, even in the presence of chimerism it is possible for certain donor tissues or cells to be rejected whereas others from the same donor are accepted (split tolerance). In a recent study, researchers used radiation chimeras and found that the radiosensitive component of NOD has a greater role in the split tolerance NOD mice develop. More Iso-Tex Diagnostics, Inc. • We are an FDA licensed manufacturer. • We label peptides, monoclonal antibodies, reagents, chemical   and proteins for cancer treatments. • Our above products can be labeled with radioisotopes such as   I-125, I-131, P32, Tc99m, Y90 and AC-225. • We have a multicurie isotope license and an animal facility.  SOCIETY NEWS Cutting Edge of Transplantation (CEOT): Buy 1, get 1 half off registration rates AST    Share    The first annual CEOT meeting taking place Feb. 14-16, 2013, brings together experts to tackle the controversies and challenges related to B cells and antibodies in transplantation. For a limited time, you can buy one registration and get one half off. This is a great opportunity for you and your colleagues to save on registration for this event. View the program, which includes over 30 speakers, and then register. C1qScreen™: A New Research Tool for AMR Risk Identify Antibodies That May Compromise Graft Survival Detect Presence of Complement Fixing Antibodies Investigate risk of developing Antibody Mediated Rejection (AMR) Request a Complimentary Sample Kit! FREE SAMPLE For Research Use Only. Not for use in diagnostic procedures. Live webinar Dec. 12: 'Transplant Cost Report 101... Understanding the Basics' AST    Share    Go to a-s-t.org/business to register for the next live webinar in the Business of Transplantation Webinar Series: It's free for AST members and only $50 for non-members. Join Alexander Aussi, BSN, MBA, at 2 p.m. EST on Wednesday, Dec. 12 to learn about transplant cost reports, acquisition services and the Medicare ratio.  TRANSPLANT NEWS Acidosis in renal transplant patients may be related to diet Renal & Urology News    Share    Diet may contribute to metabolic acidosis in renal transplant recipients (RTRs), according to investigators. In a study of 707 (RTRs), Dr. Else van den Berg, of University Medical Center Groningen in Groningen, the Netherlands, and colleagues found that patients with high intake of animal protein, such as from meat and fish, and low intake of fruits and vegetables had significantly lower serum bicarbonate and serum pH. More Transjugular intrahepatic portosystemic shunt for hepatitis C virus-related portal hypertension after liver transplantation Clinical Transplantation (subscription required)    Share    A recent study reviewed 19 consecutive liver transplant (LT) patients with hepatitis C virus (HCV)-related graft recurrent hepatitis who underwent transjugular intrahepatic portosystemic shunt (TIPS) at a median interval of 21 months (range: 5–50) from LT. Indications were refractory ascites in 11 patients (57.9 percent), hydrothorax in six (31.6 percent), and both in two (10.5 percent). Researchers concluded that TIPS may be used to treat complications secondary to HCV. More Acute liver failure, acetaminophen overdose patients displayed reduced quality of life Healio    Share    The health-related quality of life for long-term survivors of acute liver failure, particularly among acetaminophen overdose patients, was significantly lower than that of the U.S. general population according to research presented at The Liver Meeting. More Spain remains world transplant leader Fox    Share    Spain continues to be the world leader in organ donations and transplants despite the country's economic woes, according to the director of the National Transplant Organization. With the figures available up to November, Spain maintains its world leadership after beating its own record last year with a total of 4,212 transplants. More Athena Diagnostics Genetic testing can be a cost-effective way to increase the number of living related donor transplants. Mutational analysis may help direct long-term treatment plans, including pre-operative screening of potential kidney transplant recipients and living related donors. WAVES by Waters Medical Systems ✓ Hypothermic preservation of a single kidney using physiologic pulsatile preservation and membrane oxygenation: a proven technology from Waters Medical Systems (more than 40 years clinical experience) ✓ Simplifies the perfusion process (provides more options to view, chart, and trend data, offers web-based remote monitoring, and a transportable design) ✓ Meets or exceeds current FDA standards and AOPO and UNOS Preservation Guidelines. MNX: Organ Transportation When it comes to saving lives, MNX understands organ transplant logistics. Every shipment is urgent, and every step critical. That’s why MNX offers specialty services that are tailored for organ transportation. From expedited ground service to charter flights, MNX has the proven experience and operational resources you can count on. The role of belataceptin transplantation: Clinical trials in the context of other new biological immunosuppressant agents Clinical Transplantation (subscription required)    Share    Although conventional immunosuppressive agents such as calcineurin inhibitors have substantially reduced the risk of acute rejection, they have had less impact on the long-term survival. This is likely to be related to the adverse effects of such agents in terms of impaired renal function, hypertension and dyslipidemia. More Relevance of cohort studies for the study of transplant infectious diseases Current Opinion in Organ Transplantation (subscription required)    Share    The debate on the merits of observational studies as compared with randomized trials is ongoing. This review postulates an important role for cohort studies, which should not be viewed as inferior but complementary to established research tools, in particular randomized trials. More   AST eNews Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit Courtney Hodges, Content Editor, 972.402.2604    Contribute news This edition of the AST eNews was sent to ##Email##. To unsubscribe, click here. Recent issues Nov. 29 2012 Nov. 21, 2012 Nov. 15, 2012 Nov. 8, 2012 7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063