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AST
The deadline to submit your nomination for the AST Board of Director is Friday, December 6 at 5 pm ET. If you are interested in joining the AST Board, or know someone who is, we encourage you to submit your nomination. Learn more about the election process here.
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AST
The Donation Derby is a contest that supports the AST and the initiatives of your COPs. Every donation made to the AST by COP members until Dec. 31 at 11:59 PM ET will count toward the contest.
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AST
The Fellow of the American Society of Transplantation (FAST) designation application is now open to all members who meet the eligibility criteria. Instructions for the application can be found here. The deadline to apply is January 15, 2020. Don't miss out on joining this prestigious program and be recognized for your contributions to transplantation.
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Veloxis Pharmaceuticals
Now you can see the different ways that different formulations are released and absorbed in the gastrointestinal system. You’ll also have the opportunity to explore comparative pharmacokinetic results in rapid metabolizers, efficacy data over 2 years, and safety information.
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AST
The Women’s Health COP (WHCOP) often receives requests for recommended conference speakers and content experts for educational projects such as webinars. To identify and highlight members throughout our society, we are creating a Women Speakers List of AST members and their areas of expertise.
SUBMIT NOMINATION
AST
The AST sponsors a variety of Achievement Awards in recognition of AST members' achievements and contributions to the field of transplantation. The AST encourages members to nominate deserving candidates for consideration. Make your nominations by Jan. 31.
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AST
Join us for an interactive discussion on organ allocation at the 2020 Cutting Edge of Transplantation (CEoT) meeting in Phoenix, Arizona. Early bird registration is now open.
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AST
Visit the AST Member Spotlight page to read about all of the ways Linda Ohler has served AST over the years. Interested in being featured in the AST Member Spotlight? Please contact rpaulin@myast.org for more information.
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Veloxis Pharmaceuticals
There are many factors that may put a graft at risk, such as infections, nephrotoxicity, declining adherence, and inadequate immunosuppression. It can be difficult to achieve a balance between overimmunosuppression and underimmunosuppression in kidney transplant patients, putting patients at risk.
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AST
The Transplant Nephrology Core Curriculum (TNCC) is an online program jointly provided by the American Society of Nephrology and the American Society of Transplantation. The TNCC focuses on key information needed to prepare for the American Board of Internal Medicine Nephrology Board Certification and Maintenance of Certification examinations.
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AST
Transplant professionals have increasing demands on their time. Finding time in one’s day to attend conferences or to read journals is challenging. Transplant in 10 is intended to provide transplant professionals with short, easily accessible videos on key and updated topics in 10 minutes.
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AST
Transplanting Individuals with Alcoholic Hepatitis: Multidisciplinary Evaluation and Management
December 17, 2019 | 2 pm ET | Online Activity
For more information, click here.
The Journal of Heart and Lung Transplantation
Since 2005, the United States donor heart allocation system assigned patients awaiting transplantation with measurably distinct outcomes into a single high urgency priority status. In this old system, patients in cardiogenic shock as well as ambulatory stable patients with complications of a left ventricular assist device (LVAD) were allocated to a similar status of highest urgency (referred to as United Network for Organ Sharing [UNOS] Status 1A) and competed equally for donor organs. This led to overcrowding of the list within this high urgency status category with consequent prolongation of waiting times and concerns of inequity in allocation across several geographic regions.
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KidneyCare combines clinically validated AlloSure testing with AlloMap kidney and iBox to deliver personalized and Prognostic solutions for transplant patients.
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TruGraf® - The 1st and only non-invasive test to rule out “silent" subclinical rejection in stable kidney transplant recipients
The only test to be reimbursed as an alternative to surveillance biopsies
Developed by Clinicians for Clinicians
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American Association for the Study of Liver Diseases
The burden of chronic kidney disease is rising among patients with cirrhosis — it is not known what impact this has had on post-LT outcomes. All patients listed for LT in the U.S. between 2002-17 were analyzed, excluding those listed with MELD exceptions. The primary outcome was pos-LT mortality. We defined CKD pre-LT as an eGFR greater than 60 ml/min for 90 days OR ≥72 days of hemodialysis. Cox-regression determined the association between pre-LT CKD and pos-LT mortality.
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The Journal of Heart and Lung Transplantation
This study aimed to examine the intermediate-term outcomes of lung transplantation (LTx) recipients from donors after circulatory death. This ISHLT DCD Registry report with five-year follow-up demonstrated similar favorable long-term survival in DCD-III and DBD lung donor recipients at 22 experienced centers globally. These data indicate that more extensive use of DCD-LTx would increase donor organ availability and may reduce waiting list mortality.
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Decades of clinical evidence has shown that HLA-specific antibodies may lead to hyperacute antibody-mediated rejection (ABMR).
Today, ABMR remains a major challenge to successful transplantation, but detection of donor specific antibodies (DSA) is the best tool for stratifying risk. LABScreen Single Antigen Beads remain the worldwide leader for the detection of DSA.
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The Journal of Heart and Lung Transplantation
Increasing numbers of women with thoracic transplants are planning and continuing pregnancies; however, pregnancy outcomes and risks to mother and baby have not been systematically assessed. Although few maternal deaths occurred during pregnancy, in keeping with median survival data, delayed mortality for thoracic transplant recipients remains high. Despite high numbers of live births, these pregnancies continue to be at risk for hypertensive disorders, graft rejection, preterm birth and neonatal mortality.
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The Journal of Clinical Investigation
Allograft rejection is unique among immune responses in that it enlists 1%–10% of the total T cell repertoire, a proportion that up to 1,000 times greater than that observed after microbial infection. The unusual number of T cells involved is attributed to the high frequency of T cells that recognize intact, allogeneic MHC molecules. This pathway of antigen recognition is referred to as “direct” to distinguish it from the “indirect” pathway in which T cells recognize foreign antigens as processed peptides bound to self-MHC molecules.
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