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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Dec. 13, 2012


Kidney, pancreas and liver allocation and distribution in the United States
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
This special article describes the history, current status and future direction of policies regarding the allocation of kidneys, livers and pancreata for transplant in the United States, reflecting efforts to optimize allocation to help ensure effectiveness, efficiency and equity of organ sharing. More

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Buy 1 registration, get 1 half off at CEOT
AST    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Take advantage of our buy one, get one half off registration deal by securing your spot and booking your travel before the holidays. The first annual Cutting Edge of Transplantation (CEOT), taking place Feb. 14-16, 2013, promises to be an informative meeting featuring more than 30 talks. Join the experts who will tackle the controversies and challenges related to B cells and antibodies in transplantation, plus attend abstract presentations and network with others in the field. Register now.

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ATC 2012 highlights: Free on demand webcasts
AST    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Education when you want it, in less than 60 minutes! Watch webinars in the Timely Topics in Transplantation on demand webinar series: ATC 2012 highlights in infectious disease, live donor kidney outcomes, multi-organ and thoracic transplantation. These webcasts are free to AST members and can be viewed any time, at your leisure. Non-members may view the webcasts for only $25 each. Coming soon: Meeting the challenges of resistance and hepatitis management.


Echo expands number of donor hearts
MedPage today (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Stress echocardiography can identify healthy donor hearts that would historically have been rejected because of the patient's age or transient left ventricular dysfunction, Italian researchers said.

Related articles:
Test identifies rejected hearts suitable for transplant (Daily Rx)
Stress echo IDs previously rejected hearts for transplant (European Society of Cardiology via Laboratory Equipment)

Aging hepatitis C population escalates demand for liver transplantation
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
New research reveals that the greatest demand for liver transplantation due to hepatitis C (HCV)-related liver disease occurs among Americans born between 1941-1960. Findings in the December issue of Liver Transplantation suggest that continuing increased demand for transplantation is driven by the development of liver cancer in baby boomers with HCV, but that the demand may decrease as patients born in this time period continue to grow older. More

Athena Diagnostics

Genetic testing can be a cost-effective way to increase the number of living related donor transplants. Mutational analysis may help direct long-term treatment plans, including pre-operative screening of potential kidney transplant recipients and living related donors.
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New surgical technique for pediatric en-bloc kidney and pancreas transplantation: The pancreas piggy-back
Transplant International (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Combined pancreas and kidney transplantation is the therapy of choice for type I diabetes patients with associated end-stage renal disease. To counterbalance increasing waiting lists, there is a clear need to extend the organ donor pool. Although results following simultaneous pancreas and kidney transplantation (SPK) using pediatric organs are encouraging, there is still reluctance in accepting them. In this article, a novel technique using a "piggy-back" implantation of the pancreas onto the conduits of en-bloc grafted kidneys, performed in two consecutive cases, is presented. More

Transplant program biorepository poised to promote research
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Kidney transplantation is the treatment of choice for patients suffering end-stage renal disease because it provides better quantity and quality of life than other means of renal replacement therapy. Despite tremendous advances in the medical and surgical management of these patients, the short- and long-term success of this procedure is still not ideal. Therefore, the research and clinical transplant communities are engaged in a constant effort to further understand and learn the underlying biological mechanisms that preclude the desired outcomes. More

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Successful transplantation of reduced-sized rat alcoholic fatty livers made possible by mobilization of host stem cells
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a recent study, livers from Lewis rats fed with 7 percent alcohol for 5 weeks were used for transplantation. Reduced sized (50 percent) livers or whole livers were transplanted into normal DA recipients, which, in this strain combination, survive indefinitely when the donor has not been fed alcohol. However, none of the rats survived a whole fatty liver transplant while six of seven recipients of reduced sized alcoholic liver grafts survived long term. SDF-1 and HGF were significantly increased in reduced size liver grafts compared to whole liver grafts. More

Donor polymorphisms of toll-like receptor 4 associated with graft failure in liver transplant
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There have been many reports showing significant associations between recipient genetic variants and allograft outcomes, including acute rejection and graft failure, but less is known about the contribution of the donor genotype. Researchers analyzed 37 single-nucleotide polymorphisms within the toll-like receptor 4 gene from deceased donor liver allografts transplanted into 738 recipients to determine their effects on liver graft failure. More

Lipid metabolism and oxidative stress in children after liver transplantation treated with sirolimus
Pediatric Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Lipid disturbances are one of the most frequent side effects of SRL; however, clinical consequences are not known. The aim of a recent study was to evaluate the risk of AS in children after liver tranplsantation treated with SRL. More

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