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AST and ASTS comments on Proposed Rule OAR 836-053-0008
AST
The AST and ASTS provided comments on the provision in the Oregon Insurance Division's proposed rule that would establish a benchmark plan for purposes of defining essential health benefits (EHB) under the Affordable Care Act (ACA). Read the full letter to Commissioner Cali here.
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Due Monday: Submissions for research grants and AST Achievement Awards
AST
Applications for AST/TRI research grants, as well as nominations for AST Achievement Awards, are due Monday, Dec. 16. No applications or nominations will be considered after this date. Click here to submit your application for research grant funding, or submit an AST Achievement Award nomination here.
Register for the Cutting Edge of Transplantation (CEOT)
AST
Secure your spot at this intimate meeting in Chandler, Ariz., that will focus on long-term graft survival. Buy one registration at the early rate, get one half-off for a limited time only! Also, book your hotel by Jan. 24 to get the AST special discounted rate.
This activity is jointly sponsored by Global Education Group and the American Society of Transplantation. Continuing education credit will be offered for physicians, nurses, pharmacists, and transplant coordinators. Click here for full credit details. For information about accreditation of this program, please contact Global at 303-395-1782 or inquire@globaleducationgroup.com.
PRODUCT SHOWCASE
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The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
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Ureteral complications after hand-assisted laparoscopic living donor nephrectomy
Transplantation (login required)
Urological complications, namely ureteral leak and obstruction, remain a major source of morbidity after renal transplantation. Given that the existing literature on ureteral complications pertains mostly to deceased as opposed to living donors, authors aimed to assess the risk factors for ureteral complications solely after living donor nephrectomy.
Liver transplant therapy given orphan drug status
Healio
The FDA has granted orphan drug status to Conatus Pharmaceuticals for emricasan, a potential treatment for patients with chronic liver disease and acute exacerbations of chronic liver disease. The orally active caspase protease inhibitor is intended for liver transplant recipients with re-established fibrosis to delay the progression to cirrhosis and end-stage liver disease, the release said. It is designed to reduce activity of enzymes that mediate inflammation and apoptosis.
Study: Living donor comorbidities are increasing
Renal & Urology News
Complications and hospital lengths of stay after kidney donation declined from 10.1 percent and a mean 3.7 days, respectively, in 1998 to 7.6 percent and a mean of 2.5 days, respectively, in 2010, but presence of documented comorbid conditions has increased, a study of living kidney donors has revealed.
Jesse D. Schold, PhD, and colleagues reported in the Clinical Journal of the American Society of Nephrology that depression, hypothyroidism, hypertension and obesity became more prevalent among donors over time, with longer lengths of stay associated with obesity, depression, hypertension and pulmonary disorders.
3-D print of a liver for preoperative planning in living donor liver transplantation
Liver Transplantation (login required)
The growing demand for liver transplantation and the concomitant scarcity of cadaveric livers have increased the need for living donor liver transplantation (LDLT). Ensuring the safety of donors and recipients is critical. The preoperative identification of the vascular and biliary tract anatomy with 3-D printing may allow better preoperative surgical planning, avert unnecessary surgery in patients with potentially unsuitable anatomy, and thereby decrease the complications of liver transplant surgery.
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For nearly 30 years, physicians have trusted Viracor-IBT Laboratories to provide accelerated results, specialized expertise and exceptional service in transplant testing. Learn more at www.viracoribt.com.
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.
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Pretransplant aspergillus colonization of cystic fibrosis patients and the incidence of post-lung transplant invasive aspergillosis
Transplantation (login required)
Invasive aspergillosis (IA) is an important cause of morbidity and mortality among patients undergoing lung transplant. Cystic fibrosis-lung transplant recipients (CF-LTRs) may be at greater risk of IA following lung transplantation because of the presence of Aspergillus in their airways before transplantation. This study evaluated the impact of pretransplant Aspergillus colonization on the risk for IA among CF-LTRs.
Diabetes hikes infection-related death risk post-transplant
Renal & Urology News
Diabetes mellitus is an independent risk factor for infection-related death after kidney transplantation, data presented at the American Society of Nephrology's Kidney Week 2013 meeting show.
PRODUCT SHOWCASE
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Astellas is entering its 20th year focusing on transplant immunology. Today we remain steadfast in our commitment to advancing the field. Tomorrow we will seek new possibilities to help improve the transplant experience. Together. Please visit astellas.us
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The kidney as a reservoir for HIV-1 after renal transplantation
Journal of the American Society of Nephrology (login required)
Since the recent publication of data showing favorable outcomes for patients with HIV-1 and ESRD, kidney transplantation has become a therapeutic option in this population. However, reports have documented unexplained reduced allograft survival in these patients. It was hypothesized that the unrecognized infection of the transplanted kidney by HIV-1 can compromise long-term allograft function. Using electron microscopy and molecular biology, authors examined protocol renal transplant biopsies from 19 recipients with HIV-1 who did not have detectable levels of plasma HIV-1 RNA at transplantation.
Does the calcineurin inhibitor have influence on cytomegalovirus infection in heart transplantation?
Clinical Transplantation (login required)
Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality in heart transplant (HTx). The aim of this study was to analyze the rate of CMV infection in HTx patients receiving treatment with cyclosporine (CsA) or tacrolimus (Tac).
Missed last week's issue? See which articles your colleagues read most.
Role for immune monitoring to tailor induction prophylaxis in pediatric heart recipients
Pediatric Transplantation (login required)
rATG is used for HTx induction but is costly and associated with infection and PTLD. The hypothesis of a recent study was that tailoring rATG induction with CD3 monitoring results in less infection, reduced costs and similar rejection.
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