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ASN/AST Kidney Transplantation Practice Improvement Module (KTPIM)
The Kidney Transplantation PIM (KTPIM) allows you to earn Earn 20 MOC points and 20 AMA PRA Category 1 CME Credits™. With KTPIM’s carefully crafted, relevant quality measurements, you can assess and improve care for post-kidney transplant patients. KTPIM has been planned and implemented through the joint providership of the American Society of Nephrology (ASN) and the American Society of Transplantation (AST).

AST and ASN members receive a discounted fee of $220:
-ASN members register on the ASN KTPIM website
-AST members request a registration form by emailing
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COP contribution contest
To improve our external fundraising efforts, we must first improve our internal philanthropy. Achieving a high participation rate is of paramount importance. Consider a donation today.

The board will award a prize to the COP with the highest percentage of contributing members from now through the end of the year: $2,000 towards a COP initiative in 2015 (must be approved by the AST Board of Directors).

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Mark your calendar: 2015 webinars
AST has you covered for convenient education topics in January and February. Register for these webinars today and have access to the live broadcast and the archive:

Treatment of Antibody-mediated Rejection in Thoracic Transplants
  • Tuesday, Jan. 20, 2015 at 2 p.m. EST
Multiorgan Transplantation: One Organ Too Many?
  • Tuesday, Feb. 10, 2015 at 3 p.m. EST
Medically Complex Living Donors: Candidacy, Care, and Informed Consent
  • Tuesday, Feb. 17, 2015 at 2 p.m. EST
AST also has 30+ webinars available on demand, so you can watch relevant educational videos on your own schedule.

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You care about your transplant patients. And so do we. That’s why we’re introducing Astellas Cares—a new program that offers you customized tools, educational resources, and comprehensive support to help your patients care for their health. To register, visit today.

AST leader applauds Cutting Edge of Transplantation (CEOT)
Immunity and Inflammation: Engineering Cell, Gene, and Drug Therapies

Feb. 5-7, 2015
Sheraton Wild Horse Pass – Chandler, Arizona

"CEOT is a unique meeting, not only for the themes, but also a format that makes it easy to ask questions and actually learn. Smaller meeting, great speakers, and relaxed atmosphere make it great. And having this in Arizona is also a nice touch." Watch the video here

    - Anthony Jevnikar, MD
    London Health Science Center, Ontario, Canada

Bring a Friend – There is still time to take advantage of discounted “Buy One, Get One Half Off” registration now through Jan. 25. Book your hotel room by Jan. 12 to receive the lowest room rates. To view the program and register, visit

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Role of HLA-G as a predictive marker of low risk of chronic rejection in lung transplant recipients: A clinical prospective study
American Journal of Transplantation
Human leukocyte antigen G (HLA-G) expression is thought to be associated with a tolerance state following solid organ transplantation. In a lung transplant (LTx) recipient cohort, we assessed (1) the role of HLA-G expression as a predictor of graft acceptance, and (2) the relationship between (i) graft and peripheral HLA-G expression, (ii) HLA-G expression and humoral immunity and (iii) HLA-G expression and lung microenvironment.
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To find out how to feature your company in the AST eNewsletter and other advertising opportunities, Contact Tom Crist at 972-402-7724.

A 3-gene assay for monitoring immune quiescence in kidney transplantation
Journal of the American Society of Nephrology
Organ transplant recipients face life-long immunosuppression and consequently are at high risk of comorbidities. Occasionally, kidney transplant recipients develop a state of targeted immune quiescence (operational tolerance) against an HLA-mismatched graft, allowing them to withdraw all immunosuppression and retain stable graft function while resuming immune responses to third-party antigens. Methods to better understand and monitor this state of alloimmune quiescence by transcriptional profiling may reveal a gene signature that identifies patients for whom immunosuppression could be titrated to reduce patient and graft morbidities.
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  UCLA Immunogenetics Center

The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE

Diagnosis and management of antibody-mediated rejection: Current status and novel approaches
American Journal of Transplantation
Advances in multimodal immunotherapy have significantly reduced acute rejection rates and substantially improved 1-year graft survival following renal transplantation. However, long-term (10-year) survival rates have stagnated over the past decade. Recent studies indicate that antibody-mediated rejection (ABMR) is among the most important barriers to improving long-term outcomes. Improved understanding of the roles of acute and chronic ABMR has evolved in recent years following major progress in the technical ability to detect and quantify recipient anti-HLA antibody production.
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Evaluation of an immunological score to assess the risk of severe infection in heart recipients
Transplant Infectious Disease
This study previously reported how specific humoral and cellular immunological markers that are readily available in clinical practice can be used to identify heart transplant recipients (HTR) at risk of developing severe infections. In this study, they perform an extended analysis to identify immunological profiles that could prove to be superior to individual markers in assessing the risk of infection early after heart transplantation.
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Efficacy of a sun protection workbook for kidney transplant recipients: A randomized controlled trial of a culturally sensitive educational intervention
American Journal of Transplantation
A culturally sensitive educational intervention that encouraged sun protection behaviors among kidney transplant recipients (KTRs) was developed and the short-term efficacy was evaluated. Non-Hispanic White, Hispanic/Latino and non-Hispanic Black patients, who received a transplant 2–24 months prior to the study, were randomized into two study groups: intervention versus standard of care. Electronic reminders tailored to the weather conditions were sent every 2 weeks by text message or email. Self-reported surveys and biologic measurements were obtained prior to the intervention and 6 weeks later.
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Missed last week's issue? See which articles your colleagues read most.

    Azithromycin and the treatment of lymphocytic airway inflammation after lung transplantation (American Journal of Transplantation)
Summary of the British Transplantation Society Guidelines for Management of the Failing Kidney Transplant (Transplantation)
Interleukin-2 receptor antagonists for pediatric liver transplant recipients: A systematic review and meta-analysis of controlled studies (Pediatric Transplantation)
National assessment of early biliary complications after liver transplantation: Economic implications (Transplantation)
Capacity building in pediatric transplant infectious diseases: An international perspective (Pediatric Transplantation)

Don't be left behind. Click here to see what else you missed.

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Colby Horton, Vice President of Publishing, 469.420.2601
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Julie Bernhard, Executive Editor, 469.420.2647  
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