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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Dec. 20, 2012


Lung and heart allocation in the United States
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Lung and heart allocation in the United States has evolved over the past 20–30 years to better serve transplant candidates and improve organ utilization. The current lung allocation policy, based on the Lung Allocation Score, attempts to take into account risk of death on the waiting list and chance of survival post-transplant. This policy is flexible and can be adjusted to improve the predictive ability of the score. Here, researchers examine the development of U.S. lung and heart allocation policy, evaluate the application of the current policy on clinical practice and explore future directions for lung and heart allocation. More

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2013 call for committee volunteers
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AST offers members the opportunity to contribute their time and expertise through AST committees, advisory councils and communities of practice. Members that are interested in serving on an AST committee or advisory council should submit this online form. As there are only a very small number of open positions on committees and advisory councils this year, we strongly encourage member participation in one or more AST Communities of Practice (COP). COPs are open to everyone, and provide an opportunity to connect with other professionals who share your interests in a specific area. If you would like to participate in a COP, complete this survey and you'll automatically be added to the roster(s) of the COPs selected. The deadline for volunteers is Dec. 21, 2012.

On demand webinars free to AST members
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Education when you want it, in less than 60 minutes! Watch webinars in the Timely Topics in Transplantation on demand webinar series: ATC 2012 highlights in infectious disease, live donor kidney outcomes, multi-organ and thoracic transplantation. These webcasts are free to AST members and can be viewed any time, at your leisure. Non-members may view the webcasts for only $25 each. Coming soon: Meeting the challenges of resistance and hepatitis management.

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CEOT: Buy 1 registration, get 1 half off
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Register now for the first annual Cutting Edge of Transplantation (CEOT) meeting to take advantage of the buy one registration, get one half off deal. Join the experts to tackle the controversies and challenges related to B cells and antibodies in transplantation, plus attend to abstract presentations and network with others in the field. Learn more about this informative meeting by reading the latest Speaker Spotlight, and then register with your colleagues.

Transplant organizations urge Congress to pass immuno legislation
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Earlier this week a letter was distributed to leaders in the House of Representatives and Senate to urge Congress to pass the Comprehensive Immunosuppressive Drug Coverage for Kidney Transplant Patients legislation. This letter was signed by major stakeholders in the transplant community. Read the letter.

Business of Transplantation Webinar Series: Live and on demand
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Go to to register for the next live webinar in the Business of Transplantation Webinar Series: It's free for AST members and only $50 for non-members. Join Janie Oakley, MSPOD, FACHE and Laura Murdock-Stillion, MHA, FACHE, on Wednesday, Jan. 9 at 2 p.m. EST to learn about transplant regulatory frameworks. Archived versions of the November and December webinars are also available.


Immunosuppression in HCV-positive liver-transplant recipients
Current Opinion in Organ Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The purpose of this review is to evaluate the historical and recent literature as it pertains to current immunosuppression regimens in hepatitis C virus (HCV)-positive (+) liver-transplant recipients. Recent findings suggest that there are unique differences between HCV transplant recipients and non-HCV transplant recipients, not only in the graft's inflammatory response, but also to the treatments used to prevent and combat rejection. More

Transumbilical portal venous catheterization: A useful adjunct in left lobe living donor liver transplantation
Clinical Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
To improve the processes used for perfusion of the explanted graft and measuring the portal venous pressure (PVP) in adult living donor transplantation (LDLT), researchers performed transumbilical portal venous catheterization (TPVC) to reopen the umbilical vein and insert the catheter for seven adult patients undergoing left lobe LDLT. There were no major complications as a result of this procedure. This procedure prior to implanting the graft was derived from their experience and is a classic diagnostic technique used during liver surgery. It is a simple and effective procedure for perfusion and washout of the graft and for the safe monitoring of the intraoperative PVP. More

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Implantable artificial kidney could help tens of thousands: An interview with Shuvo Roy, PhD
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
With nearly 100,000 patients awaiting a kidney transplant and fewer than one-fifth likely to undergo the procedure each year, a promising hybrid device that works from the inside to provide renal functions beyond dialysis 24 hours a day, seven days a week, has the potential to change a lot of lives, not to mention substantially lower Medicare costs. More

Telaprevir-based triple therapy in liver transplant patients with hepatitis C virus: A 12-week pilot study providing safety and efficacy data
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
After liver transplantation (LT), the management of recurrent hepatitis C virus (HCV) infections still remains a major challenge. In HCV genotype 1 patients not undergoing transplantation, the introduction of protease inhibitor (PI)-based regimens has increased the sustained virological response rate significantly. This pilot study investigated both the safety and efficacy of telaprevir (TVR)-based triple therapy in HCV-infected LT patients with a special emphasis on drug-drug interactions between immunosuppressants and PIs. More

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Central adiposity predicts renal allograft failure
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A central body fat distribution, as measured by waist-to-hip ratio, is a strong and independent predictor of allograft failure in renal transplant recipients. More

Preserving the morphology and evaluating the quality of liver grafts by hypothermic machine perfusion: A proof-of-concept study using discarded human livers
Liver Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The wider use of livers from expanded criteria donors and donation after circulatory death donors may help to improve access to liver transplantation. A prerequisite for safely using these higher risk livers is the development of objective criteria for assessing their condition before transplantation. Compared to simple cold storage, hypothermic machine perfusion (HMP) provides a unique window for evaluating liver grafts between procurement and transplantation. More

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