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As 2015 comes to a close, AST would like to wish its members, partners and other transplant professionals a safe and happy holiday season. As we reflect on the past year for the field, we would like to provide the readers of the AST eNews a look at the most accessed articles from the year. Our regular publication will resume Jan. 8.
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Journal of the American Society of Nephrology
From May 15: The short- and long-term effects of unilateral nephrectomy on living donors have been important considerations for 60 years. Short-term risk is well established (0.03 percent mortality and less than 1 percent risk of major morbidity), but characterization of long-term risk is evolving. Relative to the general population, risk of mortality, ESRD, hypertension, proteinuria, and cardiovascular disease is comparable or lower.
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American Journal of Transplantation
From Nov. 13: Kidney transplantation originating from the hepatic artery has not previously been reported. Herein, we report a third kidney transplantation with the common hepatic artery as inflow. A 62-year-old male with chronic renal failure due to polycystic kidney disease was proposed to a third kidney transplantation. CT-scan showed diffuse calcification of the aorto-iliac axis and the splenic artery.
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The UCLA Immunogenetics Center (UIC) provides comprehensive testing for organ and tissue transplantation. Transplant testing has a long history at UCLA. HLA typing was pioneered here in the 1960's. The development of the microcytoxicity test in 1964 marked the beginning of international testing and standardization of HLA typing. The UCLA Immunogenetics Center has retained its leadership position in HLA research, and in the development of accompanying diagnostic testing. MORE
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AST
From Aug. 21: The AST has responded to the DHHS/NIH request for public comment on proposed "Human Immunodeficiency Virus (HIV) Organ Policy Equity (HOPE) Act Safeguards and Research Criteria for Transplantation of Organs Infected With HIV."
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American Journal of Transplantation
From Feb. 6: Live donor kidney transplantation is the best treatment option for most patients with late-stage chronic kidney disease; however, the rate of living kidney donation has declined in the United States. A consensus conference was held June 5–6, 2014 to identify best practices and knowledge gaps pertaining to live donor kidney transplantation and living kidney donation.
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Journal of Clinical Psychology in Medical Settings
From Oct. 2: The transplantation process is complex and often not well-understood by health care providers outside of such programs/ Therefore, we review the roles of medical personnel, mental health specialists, and key administrators who work together to follow federal regulations and program policies to provide quality patient care.
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American Journal of Transplantation
From March 13: Use of organs from donors testing positive for hepatitis B virus (HBV) may safely expand the donor pool. The American Society of Transplantation convened a multidisciplinary expert panel that reviewed the existing literature and developed consensus recommendations for recipient management following the use of organs from HBV positive donors. Transmission risk is highest with liver donors and significantly lower with non-liver (kidney and thoracic) donors.
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Pediatric Transplantation
From July 17: Congenital factor VII deficiency is an autosomal recessive serious disorder of blood coagulation with wide genotypic and phenotypic variations. The clinical presentation can vary from asymptomatic patients to patients with major bleedings in severe deficiency (factor VII less than 1 percent). Investigations show prolonged PT and low factor VII. Treatment modalities include FFP and repeated recombinant factor VII infusions. We hereby report the first successful LRLT for factor VII deficiency in an infant, the first-ever youngest baby reported worldwide.
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American Journal of Transplantation
From June 19: Deceased donors are labeled increased risk for disease transmission if they meet certain criteria. New PHS guidelines were recently implemented; the impact of these changes remains unknown. We aimed to quantify the impact of the new guidelines on the proportion of deceased donors labeled IRD, as well as demographic and clinical characteristics.
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Capital
From June 26: Scott Yocom was dying when his doctors at Mount Sinai suggested there was nothing more they could do for him in New York City. If he wanted to live, they said, his best chance was to fly to Cleveland. The 45-year-old architect had two decades earlier been diagnosed with Sclerosing cholangitis, a progressive disease that destroys the bile ducts inside and outside the liver. Mount Sinai has a world-class transplant team. What they don't have are organs.
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