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Home   About AST   Education   Meetings & Events   Public Policy   Contact Us   Dec. 27, 2012


As 2012 comes to a close, AST would like to wish its members, partners, and other industry professionals a safe and happy holiday season. As we reflect on the past year for the industry, we would like to provide the readers of the AST eNews a look at the most accessed articles from the year. Our regular publication will resume Thursday, Jan. 3, 2013.

Report of a consensus conference on transplant program quality and surveillance
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Aug. 2, 2012: Public reports of organ transplant program outcomes by the U.S. Scientific Registry of Transplant Recipients have been both groundbreaking and controversial. The reports are used by regulatory agencies, private insurance providers, transplant centers and patients. Failure to adequately adjust outcomes for risk may cause programs to avoid performing transplants involving suitable but high-risk candidates and donors. At a consensus conference of stakeholders held Feb. 13–15, the participants recommended that program-specific reports be better designed to address the needs of all users. More

Iso-Tex Diagnostics, Inc.

• We are an FDA licensed manufacturer.
• We label peptides, monoclonal antibodies, reagents, chemical   and proteins for cancer treatments.
• Our above products can be labeled with radioisotopes such as   I-125, I-131, P32, Tc99m, Y90 and AC-225.
• We have a multicurie isotope license and an animal facility.

Pulsatile pump decreases risk of delayed graft function in kidneys donated after cardiac death
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nov. 1, 2012: Organ storage techniques have been under scrutiny to determine the best preservation method, particularly in donation after cardiac death (DCD) kidneys. Conflicting literature on the benefit of pulsatile perfusion (PP) over cold storage (CS) warrants further investigation. Researchers analyzed the risk of developing delayed graft function (DGF) in recipients of DCD and donation after brain death (DBD) kidneys undergoing PP or CS. More

Study: Association of HLA mismatch with death with a functioning graft after kidney
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nov. 15, 2012: HLA mismatches may correlate with risk of death with a functioning graft (DWFG) because of requirement for higher immunosuppression doses and more antirejection therapy. Deceased-donor kidney transplants (n = 177 584) performed 1990–2009 and reported to the Collaborative Transplant Study were analyzed. Multivariable analysis showed that mismatches for HLA class II were more strongly associated with both hospitalization and DWFG than mismatches for HLA class I. More

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Preparing potential living kidney donors for what they will experience emotionally
American Journal of Kidney Diseases    Share    Share on FacebookTwitterShare on LinkedinE-mail article
July 5, 2012: Every year, more than 27,000 healthy individuals worldwide choose to undergo living kidney donation to improve the lives of those with end-stage renal disease. This includes both directed donation to an individual they know and nondirected donation to a stranger. Research on the outcomes of living kidney donation tends to emphasize the quantitative medical risks that donors may face in the perioperative period and long term. More

Patterns of de novo allo b cells and antibody formation in chronic cardiac allograft rejection after alemtuzumab treatment
American Journal of Transplantation (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Oct. 5, 2012: Even though the etiology of chronic rejection (CR) is multifactorial, donor specific antibody (DSA) is considered to have a causal effect on CR development. Currently the antibody-mediated mechanisms during CR are poorly understood due to lack of proper animal models and tools. In a recent study, effects of T cell depletion in the development of antibody-mediated rejection were examined using human CD52 transgenic (CD52Tg) mice treated with alemtuzumab. More

Noninvasive imaging technique may help kids with heart transplants
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
July 19, 2012: Cardiologists at Washington University School of Medicine in St. Louis have developed a noninvasive imaging technique that may help determine whether children who have had heart transplants are showing early signs of rejection. The technique could reduce the need for these patients to undergo invasive imaging tests every one to two years. More

Do kidney histology lesions predict long-term kidney function after liver transplantation?
Clinical Transplantation Journal (subscription required)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
July 26, 2012: Histological renal lesions observed after liver transplantation are complex, multifactorial and interrelated. The aims of this study were to determine whether kidney lesions observed at five years after liver transplantation can predict long-term kidney function. Ninety-nine liver transplant patients receiving calcineurin inhibitor)-based immunosuppression, who had undergone a kidney biopsy at 60 ± 48 months post-transplant, were included in this follow-up study. More

Athena Diagnostics

Genetic testing can be a cost-effective way to increase the number of living related donor transplants. Mutational analysis may help direct long-term treatment plans, including pre-operative screening of potential kidney transplant recipients and living related donors.
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✓ Meets or exceeds current FDA standards and AOPO and UNOS Preservation Guidelines.
MNX: Organ Transportation
When it comes to saving lives, MNX understands organ transplant logistics. Every shipment is urgent, and every step critical. That’s why MNX offers specialty services that are tailored for organ transportation. From expedited ground service to charter flights, MNX has the proven experience and operational resources you can count on.

Program may encourage living donors to give a kidney
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
July 26, 2012: Researchers at Johns Hopkins are testing a new program called "Live Donor Champion" that could encourage kidney donation from living donors. John Schieszer reports that it is a simple concept that could be adopted nationwide. More

New guidelines help protect the hearts of those waiting for kidney and liver transplants
AST    Share    Share on FacebookTwitterShare on LinkedinE-mail article
July 12, 2012: Scientific statement from American Heart Association addresses varied cardiac evaluation and management of transplant patients.

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Novel program cuts CMV-related admissions in transplant patients
Renal & Urology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Sept. 20, 2012: Danish researchers have developed a new program that could help dramatically lower rates of hospital admissions due to cytomegalovirus (CMV) infection among recipients of solid organ transplants (SOT). "We were able to identify a number of processes which potentially could be optimized in a systematic way in order to diagnose the infection at an earlier stage, before it causes clinical disease and where it is easier to manage," said lead investigator, Dr. Caspar da Cunha-Bang, an attending physician at the University of Copenhagen. More

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Colby Horton, Vice President of Publishing, 469.420.2601
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Courtney Hodges, Content Editor, 972.402.2604   
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