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Aug. 28, 2020

SOCIETY NEWS

NEW VIDEO: COVID-19: Answering Your Transplant Questions AST We know that information surrounding COVID-19 has been consistently changing. As the beginning stages of reopening are unfolding, we have strived to listen and answer questions and concerns from our transplant community. Recently released, this video aims to address these concerns. In this newest video, "COVID-19: Answering Your Transplant Questions", transplant recipients ask some of our physician members some questions that have arisen from the transplant community. WATCH IT NOW

Write Better Research Grants: On-Demand Workshop AST The AST Research Network is offering an on-demand webinar on research grant writing. This 1-hour workshop shares tips on how to write a successful grant application from two experienced grant reviewers. REGISTER TODAY

SPONSORED VIDEO Real-world kidney transplant experience Follow the journeys of kidney transplant patients who transitioned to a different immunosuppression regimen. After talking with their doctors about their experiences with other options, they decided to make a switch. WATCH VIDEO

FOCIS 2020 Annual Meeting FOCIS FOCIS invites you to attend the 20th anniversary of their annual meeting with an innovative lineup of topics and presenters. More than 20 scientific sessions, presented by more than 50 top clinicians and researchers from around the globe, will cover cutting-edge topics across immunology and its related fields. The opening session will feature Dr. Anthony Fauci, and the keynote addresses will be given from Nobel Laureate Dr. Tasuku Honjo, Dr. Federica Sallusto, and Dr. Irv Weissman. Presentations will be given from FOCIS founders Dr. David Hafler and Dr. Garry Fathman, Dr. Maria-Grazia Roncarolo, Dr. Carl June, Dr. Marc Feldman and Dr. Gerald Nepom, as well as a prospective look into the next 20 years. READ MORE

SPONSORED CONTENT Promoted by Natera • Natera Announces New Prospera Data at ATC Showcasing Innovation in Cell-free DNA • Natera's ProReach Program: Remote care for Prospera patients including routine labs • Natera receives final Medicare Coverage for Prospera transplant assessment test • New ProActive Registry: largest clinical utility study evaluating Prospera in >3,000 kidney transplant patients • Global, prospective multicenter study evaluating MMDx and Prospera under the leadership of Dr. Philip Halloran is now enrolling

ABIM's Summer 2020 Newsletter ABIM Check out ABIM's Summer 2020 newsletter! Recently released, this quarterly newsletter aims to keep you informed about ABIM news, share insights from fellow doctors, and let you know about opportunities to get involved with ABIM. READ MORE

COVID-19 and Transplantation: AJT Articles AST In the interest of facilitating patient care and advancing science and ensuring that accurate knowledge and experience is available to all during this current time of crisis, AJT has been expediting review of all papers dealing with COVID-19, as well as making them free to access for all. READ MORE

PRODUCT SHOWCASE The First and Only FDA-cleared digestive enzyme cartridge to Hydrolyze Fats in Enteral Formula RELiZORB mimics the function of pancreatic lipase and delivers absorbable fats to your patients. Indicated for use in pediatric patients (ages 5 years and above) and adult patients to hydrolyze fats in enteral formula. Learn more at relizorb.com REL20-310 LEARN MORE

AST Research Network AST The AST Research Network is now accepting applications for its annual career development grants cycle! The purpose of these grants is to foster the training of early career investigators who have the potential to contribute to transplant science/immunobiology and/or treatment of transplant recipients. The grants encourage continued commitment of high-quality applicants to their careers in transplantation. Applications are accepted in basic, clinical, and translational research. READ MORE

SPONSOR SPOTLIGHT

UPCOMING EDUCATION EVENTS

Effects of mTOR inhibitor-related Proteinuria on Progression of Cardiac Allograft Vasculopathy and Outcomes Among Heart Transplant Recipients AST Date and Time: Tuesday, September 8, 2020, from 2:00 PM ET to 3:00 PM ET Hosted by: The AST TCC COP and TxPharm COP REGISTER NOW

FEATURED ARTICLE Financial support for kidney transplant patients Promoted by Veloxis Pharmaceuticals Immunosuppressive medications can be a financial burden for kidney transplant patients, potentially costing as much as $10,000 to $14,000 a year. These expenses can have a negative impact on patients’ lives and may play a role in medication nonadherence, which is associated with transplant failure. Learn more about support that is available with a free 30-day trial to allow your patients to start immediately at no cost. And, for patients who are eligible with commercial insurance coverage, a $0 co-pay card offers significant savings. Find out more READ MORE

TRANSPLANT NEWS

Kidney Transplant Program Waitlisting Rate as a Metric to Assess Transplant Access American Journal of Transplantation Kidney transplant program performance in the United States is commonly measured by post‐transplant outcomes. Inclusion of pre‐transplant measures could provide a more comprehensive assessment of transplant program performance and necessary information for patient decision‐making. In this study, we propose a new metric, the waitlisting rate, defined as the ratio of patients' waitlisted in a center relative to the person‐years referred for evaluation to a program. READ MORE

PRODUCT SHOWCASE

Reach Your Prospects Every Week Thousands of industry professionals subscribe to AST's eNews, which allows your company to push messaging directly to their inboxes and take advantage of the association's brand affinity. Connect with Highly Defined Buyers and Maximize Your Brand Exposure! LEARN MORE Now offering Mobile Phlebotomy Labs@HOME is a mobile phlebotomy in-home blood draw service to aid in specimen collection directly from a patient's home. Clinicians can order and customize a number of infectious disease and transplant-relatedtesting remotely LEARN MORE

Immunosuppressive Agents and Infectious Risk in Transplantation: Managing the "Net State of Immunosuppression" Clinical Infectious Diseases Successful solid organ transplantation reflects meticulous attention to the details of immunosuppression, balancing risks for graft rejection against risks for infection. The "net state of immune suppression" is a conceptual framework of all factors contributing to infectious risk. READ MORE

SPONSOR SPOTLIGHT

Molecular Assessment of Antibody‐Mediated Rejection in Human Pancreas Allograft Biopsies Clinical Transplantation Pancreas transplant longevity is limited by immune rejection, which is diagnosed by graft biopsy using the Banff Classification. The histological criteria for antibody‐mediated rejection (AMR) are poorly reproducible and inconsistently associated with outcome. We hypothesized that a 34‐gene set associated with antibody‐mediated rejection in other solid organ transplants could improve diagnosis in pancreas grafts. READ MORE

Combined Heart-Lung Transplantation from a Donation after Circulatory Death (DCD) Donor Journal of Heart and Lung Transplantation Combined heart-lung transplantation is the optimal treatment option for many patients with end-stage heart failure and fixed severe pulmonary hypertension. It offers the only possibility of long-term survival and a return to a normal quality of life. Unfortunately, it is rarely performed due to donor organ allocation policies. We present the case of a critically ill 24-year-old man, who after waiting over 100 days in-hospital on the urgent transplant list, deteriorated further and underwent the first successful heart-lung transplant with organs from a donation after circulatory death (DCD) donor. READ MORE

The Lectin‐like Domain of Thrombomodulin is a Drug Candidate for Both Prophylaxis and Treatment of Liver Ischemia and Reperfusion Injury in Mice American Journal of Transplantation Ischemia and reperfusion injury (IRI) can occur in any tissue or organ. With respect to liver transplantation, the liver grafts from donors by definition experience transient ischemia and subsequent blood reflow. IRI is a problem not only in organ transplantation but also in cases of thrombosis or circulatory disorders such as mesenteric ischemia, myocardial or cerebral infarction. READ MORE

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