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Recent developments in transdermal delivery of therapeutics
By Dr. Afsaneh Motamed-Khorasani
Advances in recombinant DNA technology and protein-based therapeutics have affected several medical conditions, including diabetes, osteoporosis and cancer. There are multiple protein-drug products for these conditions that are often large polar complex macromolecules with side chains. This in turn, introduces stability issues and makes their delivery a difficult task to achieve. Therefore, the current routine route of administration is parenteral delivery, which is invasive and entails a historical low patient compliance.
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Pharmacists reminded of how to REACT in case of emergency
In the wake of recent violence at Michigan-based pharmacies it's safe to say plenty of people now wonder if a pharmacist's job is a safe one. Published reports show a spike in pharmacy robberies across the country. The Director of Professional Practice at the Michigan Pharmacists Association told 6 News there is a set protocol for pharmacists to follow, if faced with danger. How does a pharmacist keep their cool when a thief enters their store?
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Pharmacists meet to prepare for dispensing medical marijuana
The Hartford Courant
Pharmacists preparing for the advent of Connecticut's medical marijuana industry gathered June 25 to talk about the clinical aspects of dispensing a drug that has no federal approval nor the guidelines that go along with it. The roughly 175 people in attendance also included doctors and some owners of state-designated businesses in medical marijuana — four producers to grow it, six dispensaries to sell it.
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Omnicare agrees to pay $124 million settlement for improper pharmaceutical inducements
The Plain Dealer
Omnicare Inc., the largest provider of pharmaceutical drugs and pharmacy services in the U.S., agreed to pay more than $124 million in damages to the government, several states and a whistleblower, the Justice Department said. Omnicare, which is headquartered in Cincinnati, was accused of offering improper financial incentives to skilled nursing facilities in return for the facilities' continued selection of Ominicare to supply drugs to elderly Medicare and Medicaid beneficiaries, according to a Justice Department release.
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Prescriptions rise with new, better drugs
The Houston Chronicle
Almost half of all Americans take at least one prescription drug, and the older they are, the more medicine they're likely to take. Those are findings from the Centers for Disease Control and Prevention, which looked at prescription use from 2007 through 2010. Researchers found that the number of prescription-drug users had risen from two decades ago, when about 4 in 10 Americans had at least one prescription.
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Measles cases are spreading, despite high vaccination rates. What's going on?
The Washington Post
It's now official: Measles cases in the U.S. are at their highest level since 2000, when the disease was declared eliminated — meaning that regular, year-round transmission had been interrupted. There have been 514 cases reported this year — more than double the previous high, in 2011 — and the number is expected to continue to climb.
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FDA: Some acne products can cause serious allergic reactions
Medical News Today
The Food and Drug Administration are warning consumers who use certain over-the-counter skin products for acne to stop using them and seek emergency medical help immediately if they experience extreme allergic reactions such as feeling faint, breathing difficulties, throat tightness or swelling of the eyes, lips, face or tongue.

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Teen suicide tries increased after FDA toughened antidepressant warning
Harvard Health Publications
A few years ago, the U.S. Food and Drug Administration issued warnings that children and teens who took a common kind of antidepressant might experience suicidal thoughts. The point of the warning was to make sure that parents and doctors paid closer attention to kids taking these medications. But the plan may have backfired.

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US gets a new flu vaccine factory
NBC News
The Food and Drug Administration approved a new U.S. site to make cell-based flu vaccine, saying it will add 50 million doses to the domestic capacity for making shots. The plant in Holly Springs, North Carolina, is owned by Novartis, but it got a healthy shot in the arm with $487 million in investments by the U.S. government. The Health and Human Services Department considers U.S.-made flu vaccines an important defense against both seasonal influenza and any pandemics of new flu.

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More patients ignoring medication dosage
Big Country
"Take every 12 hours with food" — the directions are there in black and white. Yet many people pay no attention to the labels on the side of their medication bottles. "About 10 percent of hospital admissions can be linked to poor medication adherence, or not taking your medications," says Greg Young, pharmacy manager at Hendrick Medical Center in Abilene, Texas.
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Numbing medications can harm teething babies, FDA warns
CBS News
Teething infants can come to serious harm or even death from certain "gum-numbing" medications, according to a new warning from the U.S. Food and Drug Administration. The agency said June 25 that local anesthetics known as viscous lidocaine, or benzocaine-containing teething products, should never be used for teething children, except under the advice and supervision of a healthcare professional.
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FDA panel turns down fast-track approval of AstraZeneca cancer drug
The Wall Street Journal
AstraZeneca failed to win accelerated approval of a cancer drug in the U.S., dealing a blow to its new drug-development pipeline, a key plank of its defense in fighting off a $120 billion approach from Pfizer Inc. last month. The company said an advisory committee to the U.S. Food and Drug Administration voted 11-2 against accelerated approval of its experimental ovarian cancer drug olaparib in patients with a specific mutation of the disease. The FDA isn't obliged to follow the committee's recommendations, although it often does.
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Missed last week's issue? See which articles your colleagues read most.

    Can pharmacists help patients afford their drugs? (By Jason Poquette)
Health plans bring pressure to bear on drug prices (The New York Times)
Pharmacist provider status (Pharmacy Times)
Pharmacists help reduce readmissions among high-risk patients (FierceHealthcare)

Don't be left behind. Click here to see what else you missed.


AzPA Pharmacy Flash
Colby Horton, Vice President of Publishing, 469.420.2601
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Danielle Wegert, Assistant Executive Editor, 469.420.2696   
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Disclaimer: The AzPA Pharmacy Flash is a weekly roundup of articles of interest to pharmacists and pharmacy professionals. This email may contain an advertisement of AzPA and/or third party products and services. Opinions expressed in these articles do not necessarily reflect the views of AzPA or its advertising partners. The AzPA Pharmacy Flash is compiled by MultiBriefs, a division of MultiView, Inc. Factual errors are the responsibility of the listed publication.

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