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Progress in identifying the genetic roots of autism
The Wall Street Journal    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One of the most agonizing questions that parents of children with autism ask is — why? Now, a growing number of genetic tests are providing some answers. Scientists say that roughly 20 percent of autism cases can be linked to known genetic abnormalities, and many more may be discovered. More

Scientists parse genes of breast cancer's 4 major types
NPR    Share    Share on FacebookTwitterShare on LinkedinE-mail article
VideoBriefScientists have known for a while that breast cancer is really four different diseases, with subtypes among them, an insight that has helped improve treatment for some women. But experts haven't understood much about how these four types differ. A new report, published online in the journal Nature, provides a big leap in that understanding. More

Now Hiring! Disability Examination Providers

The VA Locum Tenens Program seeks physicians and psychologists to perform disability examinations for general medicine and mental health conditions. Physicians will provide compensation and pension examinations for Veterans who file for disability claims. This position requires extensive travel around the country. Compensation package includes salary and full travel. Send your CV to or contact us at 1-866-664-1030.

Down syndrome may hold key to new Alzheimer's treatments
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a new lead on Alzheimer's research, Johnson & Johnson is bankrolling a three-year pilot study of people with Down syndrome to identify the early changes that herald dementia, which afflicts up to 75 percent of adults with the condition. More

 Biotech/Diagnostics/Personalized Medicine

Genetics testing guides cancer-fighting options
Asbury Park Press    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Genetic testing is increasingly used as way for families to understand breast cancer risk and as an indicator of treatment options. The National Cancer Institute estimated that 229,060 new cases of breast cancer will be diagnosed in 2012 and, of those, 39,920 will die from the disease. Breast cancer has become "semi-epidemic," especially in the Ashkenazi Jewish population, said Arnold Pallay, director of personalized genomic medicine at Morristown and Overlook medical centers. More

Disease stabilization possible metastatic MTC with targeted therapies
OncLive    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The availability of molecular agents that target oncogenic signaling pathways now offers the possibility of achieving disease stabilization in a proportion of patients with metastatic medullary thyroid cancer, speakers agreed during a meeting of the American Thyroid Association. The more difficult questions are which patients will benefit the most from targeted therapies such as the recently approved vandetanib, and whether response will be durable enough to justify initiating treatment. More

Pharmaceutical products that make a difference
Forest has well-established franchises in the therapeutic areas of the central nervous and cardiovascular systems and are always exploring new product opportunities. MORE
Our activities touch many lives
AstraZeneca is a global, innovation-driven, integrated biopharmaceutical company. We discover, develop, manufacture and market prescription medicines for cancer, cardiovascular, gastrointestinal and infection. MORE

 Regenerative Medicine

Making it easier to make stem cells
Nature Communications via Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The process researchers use to generate induced pluripotent stem cells is time consuming and inefficient. To speed things up, researchers turned to kinase inhibitors. These chemical compounds block the activity of kinases, enzymes responsible for many aspects of cellular communication, survival and growth. As they outline in a paper published in Nature Communications, the team found several inhibitors that, when added to starter cells, help generate many more iPSCs than the standard method. More


Your patient's blood doesn't tell you that they will get tired walking the dog. Or that they've had heartburn for the past 2 weeks. But it can tell you whether or not obstructive CAD is what's causing their symptoms. You may not need to go deeper than the blood to know what's happening. MORE

Regrown bones, transplanted faces: Chemist is remaking military medicine
Wired    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Dr. Joachim Kohn, a chemist, is at the helm of a $250 million, Pentagon-funded exploit into regenerative medicine called AFIRM. His goal: to take those people ravaged by war, and help put them — quite literally — back together. More

 Emerging Medical Technologies

Medical device makers fear tax
USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Even as the new healthcare law adds millions of insured customers to the paying pool, medical device manufacturers say a tax on their product could cost them billions. The tax came as the government looked for ways to fund the new law. Insurers agreed to pay a tax beginning in 2013 because they would gain new customers. More

1st mother-daughter womb transplants performed in Sweden
CNN    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Two Swedish women have received new wombs donated by their mothers in the first mother-to-daughter uterine transplants, officials said. The first woman had her uterus removed years ago because of surgery for cervical cancer, according to the University of Gothenburg in Sweden. The second woman was born without a uterus. More

 Managed Healthcare News

Healthcare law's impact on businesses varies
USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Companies specializing in driving down spending on healthcare, whether through electronic records, preventive care or consolidating services, are turning out to be the biggest winners from the 2010 healthcare law. Investors, analysts and policymakers say any business that can help healthcare providers cut costs or keep patients from being readmitted to the hospital soon after an in-patient visit is attracting more customers and seeing more investment. More

Boom in trauma centers can help save lives, but at what price?
Kaiser Health News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Disputes are becoming more common as hospitals across the country add trauma centers at a record pace, spurred in part by the lure of greater profits. More than 200 trauma centers have opened since 2009 in more than 20 states, and another 75 hospitals are seeking approvals, according to data collected by Kaiser Health News from state health agencies. States with the greatest number of new centers include Texas, Alabama, Arizona and California. The growth reverses more than a decade of closures in the 1990s and early 2000s. More

 FDA: New Treatments and Technology

Drug study helps in search for clues on aging
The Wall Street Journal    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A drug first developed for cancer has shown promise as a treatment for progeria, a rare and fatal rapid-aging disease in children, and it may have implications in treating cardiovascular problems associated with normal aging. More

Children's prescriptions often going unfilled
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A large share of medication prescriptions to children on Medicaid may go unfilled, a new study suggests. Researchers found that of nearly 17,000 prescriptions made to children at two urban clinics, 22 percent were never filled. That's similar to what's been seen in studies of adults — among whom anywhere from 16 percent to 24 percent of prescriptions go unfilled. More

"Progeria is a rare, fatal genetic condition characterized by the appearance of accelerated aging in children. Children with progeria die of heart disease at an average age of 13, according to the Progeria Research Foundation."

Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2601
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Christine Kraly, Content Editor, 469.420.2685   
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