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Healio
Findings from two recently published articles point to a significant reduction in the number of overall solid-organ transplantation procedures performed, with the most notable decline seen in kidney transplantation.
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Cardiovascular Business
Heart transplant recipients have an increased risk of experiencing severe complications if infected with COVID-19, according to new findings published in JAMA Cardiology. The authors tracked 28 HT recipients from a single transplant program in New York City who had a confirmed COVID-19 diagnosis. The median patient age was 64 years old, 79 percent of HT recipients were men and the median time from HIT to COVID-19 diagnosis was approximately eight and a half years. The study’s authors gathered all data from March 1 to April 24, 2020.
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American Journal of Transplantation
COVID‐19 is a novel, rapidly changing pandemic: consequently, evidence‐based recommendations in solid organ transplantation remain challenging and unclear. To understand the impact on transplant activity across the United States, and center‐level variation in testing, clinical practice, and policies, researchers conducted a national survey between March 24, 2020 and March 31, 2020 and linked responses to the COVID‐19 incidence map.
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Healio
Kidneys from older donors showed no significant association with increased risk for delayed graft function, according to this study.
In addition, the research suggested that the increased risk for delayed graft function with longer cold ischemia time was not more pronounced with kidneys from older donors or with higher kidney donor profile index scores (ie, marginal kidneys).
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Veloxis Pharmaceuticals
Follow the journeys of kidney transplant patients who transitioned to a different immunosuppression regimen. After talking with their doctors about their experiences with other options, they decided to make a switch.
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American Journal of Transplantation
Non‐invasive biomarker profiles of acute rejection could impact the management of liver transplant recipients. Peripheral blood was collected following LT for discovery and validation. Blood gene profiling was paired with biopsies showing AR or ADNR as well as stable graft function samples.
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Veloxis Pharmaceuticals
Did you know there’s a transplant support system to help patients and providers with best-in-class assistance and resources? This ongoing support system assists with benefit investigation, prior authorization assistance, coordination with specialty pharmacies, prescription fulfillment navigation, and CoverMyMeds® access. There’s also a $0 co-pay card to overcome financial barriers.
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Liver Transplantation
Liver transplantation is curative for most patients with hepatocellular carcinoma; however, 10‐15 percent of patients experience HCC recurrence. Patients who are reported as within Milan criteria by imaging are frequently found to be outside criteria on explant. This understaging of HCC worsens post‐LT outcomes, however risk factors for understaging have not been elucidated. Furthermore, it is not known if there is regional or center‐level variation in understaging.
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