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.ASSOCIATION NEWS
Earn up to 30 CE hours at the ITNS Virtual Annual Meeting
Join your transplant nursing community for the first ever virtual Annual Meeting, October 22-25, 2020. Your registration gives you access to all educational sessions, e-posters and virtual exhibits for one year! Hear from experts in the field such as: Jon Kobashigawa, MD, Mark Lockwood, PhD MSN RN and more! Sign-up by September 30 to save $100 on your registration fee. Learn more.
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.INDUSTRY NEWS
An interview on the first US double lung transplant for COVID-19
ContagionLive
The greatest headlines of COVID-19 deal with big numbers—large-scale vaccination trials; massive production and distribution agreements; new testing, tracing, and prognostic projects that look to halve the ever-rising tally of new cases and mortality.
With an act that saved just one life, though, Ankit Bharat, MD, delivered a historic win for the state of COVID-19 care and capabilities.
In May, the chief of thoracic surgery and surgical director of the Northwestern Medicine Lung Transplant Program performed the first double lung transplant for a critically ill COVID-19 patient in the U.S.
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Shortsighted CMS rule change could endanger US organ transplant system
The Hill
Imagine a plan to improve a health care provider system that calls for shuttering 75 percent of its hospitals — with no backup plan for shifting patient care elsewhere. It would be disastrous, especially for patients.
In essence, that’s what a proposed CMS rule governing the United States' organ donation system entails: the change punitively targets the national network of 58 federally-funded, nonprofit Organ Procurement Organizations that orchestrate the complex, highly sensitive process of matching donors with viable organs for transplant to the most appropriate recipients.
If the rule goes into effect, up to 75 percent of these community-based OPOs, the linchpin of a transplant system acknowledged to be the best in the world, could face decertification. Yet CMS is not providing for a structured improvement agreement, appeals process, or alternative to coordinating donations and transplants in the communities that lose their OPO.
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An opt-out organ donor system could address Canada's shortage of organs for transplant
The Conversation
In 2018, there were 4,351 Canadians on waiting lists for an organ transplant. In the same year, 223 Canadians died while awaiting organ transplants.
These numbers have been growing over the last decade. For example, between 2009 and 2019, the number of Canadians in end-stage renal failure increased by 35 per cent, significantly raising the number of individuals requiring kidney transplants. The situation is only expected to worsen, as it is anticipated that more Canadians will require organ transplants over the coming years.
In the backdrop of these sobering statistics, Nova Scotia is set to become the first jurisdiction in North America to enact legislation to tackle the shortage of organs for transplant. Passed on April 2, 2019, the Human Organ and Tissue Act is scheduled to come into effect on Jan. 18, 2021.
The act institutes an “opt-out” system to organ donation, which functions on the idea of presumed consent. In its essence, this idea presumes that individuals have consented to having their organs harvested upon their death for transplantation into others in need of those organs.
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Explore some of the many factors that can put a graft at risk, including CYP3A5*1 expression, declining adherence, and nephrotoxicity. In addition, review pharmacokinetic and clinical data that may be relevant to your practice and patients.
See the Video
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Tocilizumab use in kidney transplant patients with COVID-19
Clinical Transplantation
A potential benefit of immunomodulatory agents such as tocilizumab has been reported in patients with COVID‐19 and severe pulmonary involvement. However, this therapy has been scarcely studied in kidney transplant recipients.
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Survival benefit of renal transplantation in octogenarians
Clinical Transplantation
Elderly patients are the fastest growing population requiring renal replacement therapy. As previous studies have shown a survival benefit of kidney transplantation compared to dialysis for end‐stage renal disease, researchers sought to evaluate if this survival benefit extends to octogenarians.
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Advertisement
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Veloxis Pharmaceuticals
 Immunosuppressive medications can be a financial burden for kidney transplant patients, potentially costing as much as $10,000 to $14,000 a year. These expenses can have a negative impact on patients’ lives and may play a role in medication nonadherence, which is associated with transplant failure. Learn more about support that is available with a free 30-day trial to allow your patients to start immediately at no cost. And, for patients who are eligible with commercial insurance coverage, a $0 co-pay card offers significant savings.
Find out more
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Prophylactic regimen probed as strategy to transplant HCV-infected kidneys
Renal & Urology News
Encouraging results from case series suggest it is medically feasible to transplant kidneys from hepatitis C-positive donors to HCV-negative recipients by using direct-acting antivirals, but the optimal timing and duration of DAA therapy still needs to be determined. Meanwhile, a survey of clinicians identifies a number of barriers to widespread adoption of HCV-viremic kidney transplantation to uninfected recipients.
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Considering lung transplant frailty
Physician's Weekly
The goal of lung transplantation is to improve quality of life and extend survival for patients with advanced lung disease. The degree to which individual lung transplant recipients achieve these goals is highly variable. To improve the overall success of lung transplant, it is necessary to identify factors beyond allograft function that determine key patient-centered outcomes.
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