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.ASSOCIATION NEWS
The ITNS Virtual Annual Meeting Starts Friday!
Don’t miss your chance to connect with the global transplant nursing community at #ITNS20. You can register now and access live sessions or access all education on-demand. Attendees can earn up to 30 CNE/CEPTC credits. Save $99 on your registration through October 25. Use code SAVE99. Learn more.
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.INDUSTRY NEWS
COVID-19 outcomes in patients waitlisted for kidney transplantation and kidney transplant recipients
American Journal of Transplantation
The COVID‐19 pandemic has brought unprecedented challenges to the transplant community. The reduction in transplantation volume during this time is partly due to concerns over potentially increased susceptibility and worsened outcomes of COVID‐19 in immunosuppressed recipients. The consequences of COVID‐19 on patients waitlisted for kidney transplantation, however, have not previously been characterized.
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Does the new heart transplant allocation policy encourage gaming by providers?
Michigan Medicine - University of Michigan via ScienceDaily
For the past two years, a different national allocation policy has been in effect in order to more fairly distribute hearts to those who require a life-saving transplant. People who need temporary mechanical pumps to support their hearts, like ECMO or a temporary LVAD, are now given high preference.
These mechanical pumps are meant to be markers of illness severity, and thus, identify the sickest patients who would benefit most from a heart transplant.
However, a new research letter published by scientists at the Michigan Medicine Frankel Cardiovascular Center finds clinicians gave more patients these mechanical pumps once the new policy was in place than they had previously. That in turn moves more patients up the list for a transplant.
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Follow the journeys of kidney transplant patients who transitioned to a different immunosuppression regimen. After talking with their doctors about their experiences with other options, they decided to make a switch.
Watch video
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Repeat liver transplantation in children is justified
Wiley via Medical Xpress
Repeat liver transplantation in children is justified on both medical and ethical grounds , according to potentially practice-changing research published online by the Medical Journal of Australia.
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Donor diabetes mellitus is a risk factor for diminished outcome after liver transplantation
Transplant International via MD Linx
Researchers intended to determine if there is an association between donor diabetes mellitus with early post‐transplant outcomes. Findings suggested an association of donor DM with diminished outcome early after liver transplantation. Further research is required to increase the incidence of HAT after transplantation of livers from DM donors.
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Regulatory T cells for minimizing immune suppression in kidney transplantation
The BMJ
The objective of this study was to assess whether reshaping of the immune balance by infusion of autologous natural regulatory T cells in patients after kidney transplantation is safe, feasible, and enables the tapering of lifelong high dose immunosuppression, with its limited efficacy, adverse effects, and high direct and indirect costs, along with addressing several key challenges of nTreg treatment, such as easy and robust manufacturing, danger of over immunosuppression, interaction with standard care drugs, and functional stability in an inflammatory environment in a useful proof-of-concept disease model.
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Advertisement
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Veloxis Pharmaceuticals
There are many factors that may put a graft at risk, such as infections, nephrotoxicity, declining adherence, and inadequate immunosuppression. It can be difficult to achieve a balance between overimmunosuppression and underimmunosuppression in kidney transplant patients, putting patients at risk.
Learn More
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