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University of Colorado Anschutz Medical Campus via EurekAlert!
University of Colorado researchers have found lower vaccination rates among children who receive liver transplants, increasing the risk of sickness for those children, who already face significant health issues.
The findings are discussed in a "Research Letter" included in the November 12 issue of JAMA and also call attention to data that CU School of Medicine faculty members published earlier this year in JAMA Pediatrics.
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Cardiovascular Business
Research published in the Journal of the American Medical Association Nov. 12 suggests that, despite the Organ Procurement and Transplant Network’s overhaul of the U.S. heart allocation system in 2018, CV transplant programs still suffer from variability in survival benefit and a lack of standardized guidelines for ranking candidates.
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Veloxis Pharmaceuticals
Follow the journeys of kidney transplant patients who transitioned to a different immunosuppression regimen. After talking with their doctors about their experiences with other options, they decided to make a switch.
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AASLD
In some states, liver transplantation for alcohol‐related liver disease is covered by Medicaid only with documentation of abstinence and/or alcohol rehabilitation. Different Medicaid policies may affect distribution of LT for ALD, particularly post‐2011 as centers have adopted early LT practices. Researchers surveyed Medicaid policies in all states actively performing LT, and linked state policies to prospectively collected national registry data on LT recipients from 2002‐2017 with ALD as primary listing diagnosis.
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University of Maryland Medical Center via EurekAlert!
University of Maryland School of Medicine researchers found that lung transplant recipients who had early signs of organ rejection could increase their chances of survival by using an inhaled form of the immunosuppression drug cyclosporine. This is the first randomized, controlled study to demonstrate increased survival and improved lung function using an investigational form of cyclosporine called liposomal cyclosporine, which can be inhaled. It is used in combination with an investigational nebulizer to deliver the drug to the lungs.
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Veloxis Pharmaceuticals
Did you know there’s a transplant support system to help patients and providers with best-in-class assistance and resources? This ongoing support system assists with benefit investigation, prior authorization assistance, coordination with specialty pharmacies, prescription fulfillment navigation, and CoverMyMeds® access. There’s also a $0 co-pay card to overcome financial barriers.
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University of Illinois at Chicago via EurekAlert!
Researchers at the University of Illinois at Chicago report that among patients with obesity, robotic kidney transplants produce survival outcomes comparable to those seen among nonobese patients.
Their study, published in the American Journal of Transplantation, includes data collected over 10 years from more than 230 robotic-assisted kidney transplants in patients with obesity.
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Dove Press
Advances in surgical techniques and immunosuppressive agents have made solid organ transplant an important strategy for treatment of end-stage organ failures. However, the incidence of infections following Tx due to Gram-negative pathogens is on the rise. These infections are associated with increased mortality and morbidity in patients following transplantation, including liver Tx. Thus, managing infections in liver Tx recipients is a big challenge, requiring prompt medical attention.
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BMC Infectious Diseases via MD Linx
Given the possibility for poor outcomes in solid organ transplant recipients and cardiovascular diseases in the general population in correlation to human cytomegalovirus infection or disease, researchers examined HCMV seroprevalence and titre with regard to age distribution and compared these between SOT recipients and healthy individuals in South Korea.
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AASLD
A previous study at Indiana University demonstrated a reduction in myocardial infarction incidence with increased frequency of cardiac catheterization in liver transplant candidates. A strict protocol for performing CATH based upon predefined risk factors, rather than non‐invasive testing alone, was applied to a subgroup from that study. CATH was followed by percutaneous coronary intervention in cases of significant coronary artery disease. The current study applies this screening protocol to a larger cohort to assess post‐LT clinical outcomes.
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