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The Online CCTC and CCTN Review Course is a comprehensive program for transplant nurses preparing for the CCTC and CCTN examinations. Based on the American Board for Transplant Certification’s test blueprints and the 2nd edition of the Core Curriculum for Transplant Nurses, this course includes general transplantation and organ-specific topics as well as information on test-taking strategies.
The review course will be offered in 11 modules, which can be purchased individually or as a package. Participants will earn CE and CEPTC credits for completing each module. Currently, 6 modules are available for purchase, with the remaining modules being released later in 2019.
The Journal of Heart and Lung Transplantation
Since 2005, the United States donor heart allocation system assigned patients awaiting transplantation with measurably distinct outcomes into a single high urgency priority status. In this old system, patients in cardiogenic shock as well as ambulatory stable patients with complications of a left ventricular assist device were allocated to a similar status of highest urgency (referred to as United Network for Organ Sharing [UNOS] Status 1A) and competed equally for donor organs. This led to overcrowding of the list within this high urgency status category with consequent prolongation of waiting times and concerns of inequity in allocation across several geographic regions.
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American Association for the Study of Liver Diseases
The burden of chronic kidney disease is rising among patients with cirrhosis — it is not known what impact this has had on post-LT outcomes. All patients listed for LT in the U.S. between 2002-17 were analyzed for this study, excluding those listed with MELD exceptions.
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Veloxis Pharmaceuticals
Follow the journeys of kidney transplant patients who transitioned to a different immunosuppression regimen. After talking with their doctors about their experiences with other options, they decided to make a switch.
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The Journal of Heart and Lung Transplantation
This study aimed to examine the intermediate-term outcomes of lung transplantation recipients from donors after circulatory death. This ISHLT DCD Registry report with five-year follow-up demonstrated similar favorable long-term survival in DCD-III and DBD lung donor recipients at 22 experienced centers globally. These data indicate that more extensive use of DCD-LTx would increase donor organ availability and may reduce waiting list mortality.
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The Journal of Heart and Lung Transplantation
Increasing numbers of women with thoracic transplants are planning and continuing pregnancies; however, pregnancy outcomes and risks to mother and baby have not been systematically assessed. Although few maternal deaths occurred during pregnancy, in keeping with median survival data, delayed mortality for thoracic transplant recipients remains high. Despite high numbers of live births, these pregnancies continue to be at risk for hypertensive disorders, graft rejection, preterm birth and neonatal mortality.
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Veloxis Pharmaceuticals
There are many factors that may put a graft at risk, such as infections, nephrotoxicity, declining adherence, and inadequate immunosuppression. It can be difficult to achieve a balance between overimmunosuppression and underimmunosuppression in kidney transplant patients, putting patients at risk.
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Clinical Transplantation
Inequities in health care predispose Indigenous populations to poor health outcomes. The objective of this study is to examine patient survival and other post-transplant outcomes of kidney transplantation among Indigenous patients compared to non-Indigenous populations.
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Transplantation
Women with absolute uterine-factor infertility until recently only had the opportunity to have children through adoption, foster parenting, or gestational surrogacy. However, for some women with AUFI, none of these options are possible because of religious, societal, personal, or other reasons. Uterus transplantation has recently been introduced as a unique opportunity for both genetic and gestational motherhood.
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The Journal of Clinical Investigation
Allograft rejection is unique among immune responses in that it enlists 1–10 percent of the total T cell repertoire, a proportion that up to 1,000 times greater than that observed after microbial infection. The unusual number of T cells involved is attributed to the high frequency of T cells that recognize intact, allogeneic MHC molecules. This pathway of antigen recognition is referred to as “direct” to distinguish it from the “indirect” pathway in which T cells recognize foreign antigens as processed peptides bound to self-MHC molecules.
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Clinical Transplantation
Hanging donors are considered as marginal donors and frequently unsuitable for lung transplantation. However, there is no evidence of higher lung transplantation morbidity‐mortality with lungs provided by hanging donor.
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