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Targeting critical pathways

We are improving cancer treatment by developing monoclonal antibodies that target cancer stem cells.

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Multiple Myeloma: An Update on Diagnostic and Treatment Strategies

Advanced Treatment of Osteoporosis in Postmenopausal Women

Decreasing the Cost Burden of Fibromyalgia with Early Diagnosis and Management


 Managed Healthcare News
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GAO: Secrecy on medical device prices hurts buyers
Star Tribune    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Hospitals are paying widely varying prices for the same implantable medical devices, according to a new study that suggests secretive sales agreements prevent many buyers from getting the best deals. The report from the U.S. General Accounting Office — which turned up a difference of more than $8,000 for one cardiac device alone — found that confidentiality clauses in sales contracts keep even the physicians who decide which devices to use in the dark about prices. More

Coming soon: Nutrition labels for health insurance
The Washington Post    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The White House has finalized standardized labels for health insurance plans. Think of them as nutrition facts for a plan that outline a its deductible, out-of-pocket limits and costs for visits to the emergency room or primary care doctor. The labels have been in the works for over a year and got caught in some tussling between insurance industry and consumer advocates. More

New rule requires plain language about health plan benefits, coverage    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Departments of Health and Human Services, Labor and Treasury have published final regulations that require health insurers to eliminate technical or confusing language from their marketing materials. Under the rule announced recently, health insurers must provide consumers with clear, consistent and comparable summary information about their health plan benefits and coverage. More

ACP points to 37 commonly misused screenings, tests
American Medical news    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When a patient asks for a screening or diagnostic test, physicians should ask themselves whether the results will change how they care for him or her, says the editor of Annals of Internal Medicine. "If the answer is no, then there is probably little reason to order it," Annals Editor Christine Laine, MD, M.P.H., wrote in an editorial in the Jan. 17 issue of the journal, which also featured an article from the American College of Physicians listing 37 common clinical situations in which screening and diagnostic tests provide little benefit. More

'Model' managed care dental program proves painful
Center for Health Reporting via The Sacramento Bee    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Almost two decades ago, the state of California made Sacramento County its testing ground for a new model of delivering dental care to poor children. Officials envisioned a managed care system that would control costs and improve children's ability to see a dentist. Today that model persists — but state data show the county consistently produces one of California's worst records for care. More

 FDA: New Treatments & Technology

FDA outlines path for lower-priced biotech drugs
USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Food and Drug Administration is preparing to review the first lower-cost versions of biotech drugs, expensive medications which have never before faced generic competition. The guidelines are the final step in a decades-long effort to lower the price of biotech drugs, high-tech injectable medications that cost billions of dollars each year. More

FDA admits to monitoring email seeking leak
The Washington Post    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Food and Drug Administration said it monitored the personal emails of employees who had concerns about unsafe medical devices but said it did so to investigate allegations that employees had leaked confidential information. The statement came after a media report that the FDA intercepted and stored the email communications of agency doctors who raised concerns with Congress about the FDA approving cancer-screening and other devices. More

Stem cells and the lawsuit that could shape medical future
Forbes    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Regenerative Sciences, a medical company that pioneered a procedure to treat orthopedic injuries using patients' own stem cells, is fighting the Food and Drug Administration over a claim that human cells should be federally regulated as drugs, in a landmark case that has far-reaching implications for the future of regenerative medicine. More

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The world’s first remote glucose monitor designed to provide protection from overnight hypoglycemia. MORE
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AstraZeneca is a global, innovation-driven, integrated biopharmaceutical company. We discover, develop, manufacture and market prescription medicines for cancer, cardiovascular, gastrointestinal and infection. MORE

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Critical shortage of children's leukemia drug called 'national crisis'
ABC News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Medication used to treat the most common form of childhood leukemia is in short supply, adding to the largest nationwide shortage of critical lifesaving hospital medications in nearly a decade. All five pharmaceutical companies that make the injection drug methotrexate have either slowed and stopped manufacturing the drug, according to the U.S. Food and Drug Administration. If the shortage continues, physicians and pharmacists fear thousands of children will be left without lifesaving treatment. More

Skin cancer drug reverses Alzheimer's in mice
CNN    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists say they "serendipitously" discovered that a drug used to treat a type of cancer quickly reversed Alzheimer's disease in mice. In the study, researchers gave mice mega-doses of bexarotene, a drug used to treat a type of skin cancer. Within 72 hours, the mice showed dramatic improvements in memory and more than 50 percent a hallmark of Alzheimer's disease had been removed from the brain. More

Pregnant with breast cancer: Tough choices, new hope
ABC News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemotherapy for breast cancer can be safe during the second and third trimesters of pregnancy, according to a new report in The Lancet. And terminating the pregnancy does not appear to improve the mother's prognosis. More

 Prevention & Wellness
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The link between obesity and early maternal-child relationship
The Atlantic    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The standard advice for weight loss is to eat less and exercise more. Although a sound approach, the strategy appears to fall short in the war against obesity, particularly among children. A study proposed a different take on overweight prevention starting in early childhood. Instead of focusing on the body's energy balance, researchers suggest improving the mother-toddler relationship. More

Nearly 1 in 20 US adults older than 50 have fake knees
The Associated Press via Yahoo News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nearly 1 in 20 Americans older than 50 have artificial knees, according to the first national estimate showing how common these replacement joints have become in an aging population. The estimate is important because it shows a big segment of the population might need future knee-related care, said Dr. Daniel Berry, president of the American Academy of Orthopedic Surgeons and chairman of orthopedic surgery at the Mayo Clinic in Rochester, Minn. More

Diagnosing depression: A simple blood test?
HealthDay via MedlinePlus    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Could a simple blood test one day help doctors diagnose cases of depression? When mental healthcare providers suspect someone has depression, they rely on symptoms to help make the diagnosis, but some cases do slip through. Now, a new study finds a blood test may provide much-needed information for identifying this illness, which affects an estimated 1 in 10 U.S. adults. More

 Genomics and Biotech
Click Here to visit the Genomics, Biotech & Emerging Medical Technology Institute

Researchers: Cancer drug reverses Alzheimer's symptoms in mice
Bloomberg News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A skin cancer drug sold by Eisai Co. reversed signs and symptoms of Alzheimer's disease in mice, according to a study in Science, setting the stage for tests to see if the treatment can do the same in humans. More

Study: Curcumin slows prostate cancer growth
Food Product Design    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Curcumin, an active component of turmeric, may help slow down tumor growth in castration-resistant prostate cancer patients on androgen deprivation therapy, according to a study from researchers at Jefferson's Kimmel Cancer Center. Curcumin was found to suppress p300 and CPB, two nuclear receptor activators that help tumor cells bypass ADT, thus squashing the success of the therapy. More

New molecule has potential to help treat genetic diseases, HIV    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemists at the University of Texas at Austin have synthesized a molecule that can entangle itself in a specific sequence of DNA and stay attached for 16 days, longer than any other molecule reported. It's an important step along the path to someday creating drugs that can go after rogue DNA directly. Such drugs would be revolutionary in the treatment of genetic diseases, cancer or retroviruses such as HIV. More

 Behavioral Health
Click Here to visit the Behavioral Health Institute

Why looks can be deceiving
Science Codex    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It's Valentine's Day, he forgot to bring flowers — and somehow that painfully sad look on her face simply is not registering in his mind. Could it be a problem in his prefrontal cortex? More

Facebook takes a toll on your mental health
MSNBC    Share    Share on FacebookTwitterShare on LinkedinE-mail article
According to three new studies, Facebook can be tough on mental health, offering an all-too-alluring medium for social comparison and ill-advised status updates. And while adding a friend on the social networking site can make people feel cheery and connected, having a lot of friends is associated with feeling worse about one's own life. More

In older adults, fluctuating sense of control linked to cognitive ability
Medical Xpress    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Everyone has moments when they feel more in control of their lives than at other times. New research from North Carolina State University shows this sense of control fluctuates more often, and more quickly, than previously thought — and it may affect cognitive abilities. More

Are you a cyberchondriac?
GoLocalProv    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In increasing numbers, patients arrive for a medical appointment with their own diagnoses of illnesses they're not even close to experiencing. It's cyberchondria, an unfounded anxiety concerning one's wellness brought on by visiting health and medical websites, and it's on the rise like an out-of-control flu season. More

"Mississippi had the highest rate of adult obesity in the United States, according to a recent Robert Wood Johnson Foundation report. Colorado had the lowest rate."
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