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April 27, 2023

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SCMR NEWS

Updates from the SCMR Registry Committee
Dipan Shah, MD
SCMR Registry Committee Chair

The SCMR Registry now has more than 150,000 CMR scans from 22 US-based sites!

I am excited to take over as chair of the SCMR Registry committee and would especially like to thank the Immediate Past chair Lon Simonetti, past vice-chair Han Kim, and Bob Judd from Intelerad for all their efforts in organizing and growing the Registry over the past few years.

The multi-center SCMR Registry serves as a central repository to provide robust real-world clinical data to support outcomes research, quality improvement, cost-effectiveness evaluation, and machine learning as a worldwide collaborative effort. There are currently 20 ongoing multi-center projects, with new projects being added monthly. Numerous registry-based abstracts were presented at the recent scientific sessions of the American College of Cardiology in New Orleans.

Further information on the SCMR Registry can be found at https://scmr.org/page/Registry

I am pleased to highlight an SCMR Registry project which was recently presented at the Annual Scientific Sessions of the American College of Cardiology in New Orleans and concurrently published in the Journal of the American College of Cardiology. This multicenter project from Houston Methodist Hospital, Duke University, Piedmont Heart Institute, and Atrium Health underscores the strength of the SCMR Registry Platform:

Influence of Cardiac Remodeling on Clinical Outcomes in Patients with Aortic Regurgitation: Data from the AR Consortium of the SCMR Registry


This multi-center study from the SCMR Registry included 458 asymptomatic patients with preserved LV ejection fraction and moderate or severe aortic regurgitation on CMR. Patients were followed longitudinally for the development of symptoms or decrease in LVEF to <50%, development of guideline indications for surgery based on LV dimensions, or death under medical management. The authors identified optimal CMR-derived quantitative thresholds associated with the development of the outcomes and demonstrated that CMR-derived volumetric measures of LV remodeling were superior to current guideline-recommended linear LV diameters. Read More


2023 CMR Board Review Course
The 2023 CMR Board Exam Review Course, which took place live on 1-2 April 2023, is still available till April 2024 in the SCMR Online Learning Portal. Organized by SCMR, this course is intended as preparation for physicians undertaking the Certification Board of Cardiovascular Magnetic Resonance (CBCMR) examination by the Alliance for Physician Certification & Advancement™ (APCA™). The CBCMR examination assesses candidates on their knowledge, skills and abilities in preparing patients for CMR studies, selecting appropriate protocols, conducting CMR studies in a spectrum of scenarios whilst interpreting the results, and performing post-processing tasks.

#SCMR23 Abstracts Now Available in the Whova App
For 2023 SCMR conference attendees, check out the abstract book in the Whova conference app or webportal under the "Resources" menu. Download Mobile app

Last Few Days to Claim Your CME for #SCMR23
Please take a few moments to complete the SCMR Virtual Scientific Sessions CME/CE evaluation by April 29th, 2023. Your feedback is important to us as we plan for future Scientific Sessions. To claim CME, MOC, CE, and/or ASRT credit, you are required to complete relevant evaluation(s) and/or quizzes (if claiming MOC credit for ABP) for the sessions for which you want to claim credit. Once you have completed the evaluation, you will be able to download and print your certificate(s). Please complete your evaluations on the SurveyMagnet platform and select the credit type(s) to claim.


SCMR Podcast — New Episode!
The SCMR Podcast was launched in October 2022 and aims to inform SCMR members and CMR users in general on new developments in the society, as well as CMR techniques and logistics. 3 episodes have been published so far — listen here on Spotify. The February 2023 edition provided a live report of the #SCMR23 scientific meeting, including interviews with participants and historical interviews with two SCMR giants: SCMR founder Gerald Pohost, MD, MSCMR, and Roderic Pettigrew PhD, MD. In the most recent episode (just released) for May 2023 the main topic is the drive toward an all-in-one CMR exam with 15 minute door-to-door time; and three VIP guests joint the discussion — Karen Ordovas MD, FSCMR, (President 2023), Sven Plein MD, PhD (immediate past President) & Reza Nezafat, PhD. If you would like to join as a guest, or if you have suggestions for topics to be discussed, please let us know by email: scmrpodcast@gmail.com. Initially, SCMR Podcast episodes are planned every 3 months on the first day of the month, with the following schedule: May, August, November, February.


SCMR Meetings!
Congenital Heart Disease, June 2023, Munich — REGISTER NOW

We invite you to attend the SCMR mid-year meeting on CMR in Congenital Heart Disease in June! We are excited to bring you 2 days of learning, inspiration, and networking — covering recent advances in Congenital Heart Disease imaging, scientific abstracts & a hands-on course including live-scanning, post-processing & case reviews.

PRELIMINARY AGENDA

EARLY BIRD RATES NOW EXTENDED to May 10


Stress CMR, July 2023, Washington DC — REGISTER NOW

We invite you to attend the SCMR mid-year mini-course on stress CMR and quantitative myocardial perfusion in June! We are excited to bring you 2 days of learning, inspiration, and networking. The program is designed to be interactive and to help improve your skills at performing and interpreting stress CMR. Each topic will receive a dedicated session with presentations by world experts on the matter — from the basics to state-of-the-art & advanced applications of stress CMR. There will additionally be numerous stress CMR case review sessions presented from many busy CMR programs from around the world. There will also be the opportunity to sign up for hands-on sessions where you will analyze stress CMR cases using currently available software with the help of our expert faculty.


CardioRheumatology, August 2023, Amsterdam — REGISTER NOW

Announcing the first SCMR-endorsed cardio-rheumatology course! This will take place in the Auditorium of Reade, Amsterdam on Thursday August 24th - one day before ESC congress takes place in Amsterdam from August 25th-28th in Amsterdam. Cardiac involvement is increasingly recognised in rheumatological diseases, with CMR becoming central to management in several clinical scenarios. Learn more about the course & register here.


The Global CMR Conference, January 2024, London

Save the date for the CMR event of 2024!


IN THE SPOTLIGHT


Apical Ischemia — A Hallmark Feature of Apical HCM?
Rebecca K Hughes, MBBS
Cardiology PhD fellow, UCL Institute of Cardiovascular Science

Although accounting for only 10% of HCM cases, apical HCM is increasingly recognised, thanks in part to superior visualization of the LV apex with CMR. With a typically ischemic-appearing ECG and many patients complaining of chest discomfort, the role of ischemia in apical HCM is often postulated. Last month, Circulation: Cardiovascular Imaging published our new paper exploring apical ischaemia in 100 apical HCM subjects using quantitative perfusion mapping CMR. We discovered a remarkable finding: that apical perfusion defects were present in 100% of patients, occurring across the entire disease spectrum; from those with morphologically mild disease (with minimal hypertrophy and no scar) to those with advanced disease (significant hypertrophy, scar, and apical aneurysms) suggesting that apical microvascular ischaemia is tightly linked with the underlying pathophysiology of apical hypertrophy. Although the universal presence of apical perfusion defects cannot be used for prognostication, it may have future use as a potential imaging biomarker, aiding diagnosis in morphologically mild disease. The degree and extent of ischemia varied, offering scope for future work to understand how the degree of ischemia (myocardial blood flow) links to disease progression and risk. This paper offers new insights into this disease and raises many more questions that need answering in future studies.

CONGENITAL HEART DISEASE CORNER

by Kanwal Farooqi, MD

The next Multicenter Collaborative Research subcommittee member meeting and project proposal submission deadline is upcoming! Our next meeting will be May 19th — be on the lookout for Zoom invites. If you have a project you would like to propose, please send a few slides to Simon Lee (sxl086@icloud.com) by May 5th. As always, if you have any questions or would like some help, feel free to reach out to Heynric, Rebecca, or Simon by email. In another piece of exciting news, this Summer we will be asking for applications for a cardiology advanced imaging or pediatric radiology imaging Fellow-In-Training member of our leadership group. More information to come at our meeting in May.

CMR JOURNAL CLUB


CASES OF SCMR


Had an interesting case? At Cases of SCMR we are interested in cases where CMR was essential in diagnosis and management. Submissions of multi-imaging modality cases are encouraged. Check out the full archive here. Submitted cases will be peer-reviewed by the web committee before acceptance and can be listed as a peer-reviewed web publication on CVs. All published cases for the year are published together in an end-of-year JCMR round-up. If that isn't enough, the editorial team will select finalists from the year's submissions to present their case at the next Annual SCMR Scientific Sessions — the winner will be recognized at the closing plenary session in London! Cases published or under consideration for publication elsewhere or that have been previously presented at SCMR Scientific Sessions will not be accepted. Learn how to submit here.


#WhyCMR — SOCIAL MEDIA

22 March to 21 April 2023 #WhyCMR Activity
Each month our social media committee correspondents update us on the latest #WhyCMR activity stats and most popular tweets or threads. Join the conversation and use the #WhyCMR in your social media posts and follow @SCMRorg!




Tweet of the Month


Manish Motwani MB ChB, FSCMR
SCMR NewsBeat editor

NEWS FROM THE FIELD

Safety of Magnetic Resonance Imaging in Patients with Surgically Implanted Permanent Epicardial Leads
Heart Rhythm
Magnetic resonance imaging (MRI) safety in patients with an epicardial cardiac implantable electronic device (CIED) is uncertain. This study aimed to assess the safety and adverse effects of MRI in patients who had surgically implanted epicardial CIED. Read More

Abnormal Mechanics Relate to Myocardial Fibrosis and Ventricular Arrhythmias in Patients with Mitral Valve Prolapse
Circulation: Cardiovascular Imaging
The relation between ventricular arrhythmia and fibrosis in mitral valve prolapse (MVP) is reported, but underlying valve-induced mechanisms remain unknown. Researchers evaluated the association between abnormal MVP-related mechanics and myocardial fibrosis, and their association with arrhythmia. Read More

Comprehensive Cardiovascular Magnetic Resonance Tissue Characterization and Cardiotoxicity in Women With Breast Cancer
JAMA Cardiology
There is a growing interest in understanding whether cardiovascular magnetic resonance (CMR) myocardial tissue characterization helps identify risk of cancer therapy-related cardiac dysfunction (CTRCD). This study aimed to describe changes in CMR tissue biomarkers during breast cancer therapy and their association with CTRCD. Read More

Contrast-Enhanced Cardiac Magnetic Resonance Imaging with a Manganese-Based Alternative to Gadolinium for Tissue Characterization of Acute Myocardial Infarction
Journal of the American Heart Association
Background Late gadolinium enhancement cardiac magnetic resonance imaging is an effective and reproducible method for characterizing myocardial infarction. However, gadolinium-based contrast agents are contraindicated in patients with acute and chronic renal insufficiency. Read More

Cardiac MRI: State of the Art
Radiology
Cardiac MRI plays an important role in the evaluation of cardiovascular diseases (CVDs), including ischemic heart disease, cardiomyopathy, valvular disease, congenital disease, pericardial disease and masses. Large multicenter trials have shown the positive impact of MRI-based management on outcomes in several CVDs. Read More

Myocardial Scar and Revascularization on Mortality in Ischemic Cardiomyopathy (from the Late Gadolinium Enhancement Cardiac Magnetic Resonance Study)
The American Journal of Cardiology
Myocardial viability test to guide revascularization remains uncertain in patients with ischemic cardiomyopathy. Researchers evaluated the different impacts of revascularization on cardiac mortality according to the extent of myocardial scar assessed by cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) in patients with ischemic cardiomyopathy. Read More

Cardiovascular Magnetic Resonance Imaging in Patients with Ibrutinib-Associated Cardiotoxicity
JAMA Oncology
Ibrutinib has been associated with serious cardiotoxic arrhythmias. In preclinical models, these events are paralleled or proceeded by diffuse myocardial injury (inflammation and fibrosis). Yet whether this is seen in patients or has implications for future cardiotoxic risk is unknown. Read More

Multi-Imaging Characterization of Cardiac Phenotype in Different Types of Amyloidosis
JACC: Cardiovascular Imaging
Bone scintigraphy is extremely valuable when assessing patients with suspected cardiac amyloidosis (CA), but the clinical significance and associated phenotype of different degrees of cardiac uptake across different types is yet to be defined. Read More

Manganese-Enhanced Magnetic Resonance Imaging of the Heart
Journal of Magnetic Resonance Imaging
Manganese-based contrast media were the first in vivo paramagnetic agents to be used in magnetic resonance imaging (MRI). The uniqueness of manganese lies in its biological function as a calcium channel analog, thus behaving as an intracellular contrast agent. Read More

Ferumoxytol-Enhanced MRI in Children and Young Adults: State of the Art
AJR American Journal of Roentgenology
Ferumoxytol is an ultrasmall iron oxide nanoparticle that was originally approved by the FDA in 2009 for IV treatment of iron deficiency in adults with chronic kidney disease. Subsequently, its off-label use as an MRI contrast agent increased in clinical practice, particularly in pediatric patients in North America. Read More

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