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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Jan. 8, 2014

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SLAS2014 advance registrations accepted until Jan. 17
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Be sure you are among the thousands who will learn about the latest life sciences R&D breakthroughs at SLAS2014, Jan. 18-22, San Diego. Preregistered attendees can pick up their conference badges beginning at 7:30 a.m. Saturday, Jan. 18 in the Hall G lobby of the San Diego Convention Center. Admission is free for those choosing to visit the 300-company exhibition only, but registration is required. More

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SLAS ELN Reports: Integrating Chemical Synthesis into the Discovery Process to Speed Lead Optimization
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Technological improvements in automation for chemistry are fueling the integration of chemical synthesis into the discovery process, making it possible to purify, analyze and screen lead compounds faster and more efficiently. Dave Parry, SLAS2014 session chair and CEO of Cyclofluidic in Hertfordshire, UK, offers insights into some recent innovations in this arena in the SLAS Electronic Laboratory Neighborhood e-zine. More

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Exhibitors compete for SLAS New Product Award Designations at SLAS2014
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"The SLAS Annual Conference and Exhibition has emerged as an exceptionally popular and important place for companies to launch new products," says 2013 SLAS President Jeff Paslay. "Last year, more than 60 new products were unveiled at SLAS2013." Check the SLAS2014 website for the growing list of new products scheduled to make their debut at SLAS2014. More

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JBS special issue on phenotypic drug discovery part two now online
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SLAS Biomolecular Sciences Section members and JBS subscribers can now view the January issue, including review articles on "Phenotypic Screening Targeting Neurodegenerative Diseases" and "Inhibition of Microglia Activation as a Phenotypic Assay in Early Drug Discovery." This is part two of a two-part special issue on modern PDD, or physiology-based, strategies by guest editors Jonathan A. Lee and Ellen L. Berg. View part one. More





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SLAS Member Center — the hub for all things SLAS at SLAS2014
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When exploring the SLAS2014 Exhibit Hall, be sure to stop by the SLAS Member Center. Sign up for career counseling, check out the job board, learn more about JALA and JBS, attend journal author and LabAutopedia editor Meet & Greet sessions, watch Southern California F.I.R.S.T. teams demonstrate their robots, meet The Lab Man, connect with attendees in the SLAS Global Village and more. More


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Reminder: Vote in the 2014 JALA & JBS Art of Science Contest
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Have you voted for your favorite finalist in the 2014 JALA & JBS Art of Science Contest? Be sure to do so, and share this link with all who appreciate the artistic value of scientific images to captivate and communicate. Online voting ends Jan. 31 and will determine the grand prize winner of a $500 Amazon gift card. SLAS members and nonmembers are invited to vote. Watch a video of the finalists. More

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Team discovers new compounds that challenge the foundation of chemistry
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All good research breaks new ground, but rarely does the research unearth truths that challenge the foundation of a science. That's what Artem R. Oganov has done, and the professor of theoretical crystallography in Stony Brook University's Department of Geosciences will have his work published in the Dec. 20 issue of the journal Science. The paper titled "Unexpected stable stoichiometries of sodium chlorides," documents his predictions about, and experiments in, compressing sodium chloride — rock salt — to form new compounds. More

Discovery and saturation analysis of cancer genes across 21 tumor types
Nature    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Although a few cancer genes are mutated in a high proportion of tumours of a given type (>20%), most are mutated at intermediate frequencies (2–20%). To explore the feasibility of creating a comprehensive catalog of cancer genes, we analyzed somatic point mutations in exome sequences from 4,742 human cancers and their matched normal-tissue samples across 21 cancer types. We found that large-scale genomic analysis can identify nearly all known cancer genes in these tumor types. More

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Calculating cancer
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Cancer is a dynamic, adaptive system consisting of billions of normal and tumor cells interacting at multiple spatial and temporal scales. To many cancer biologists and oncologists, the complexity of cancer seems beyond comprehension. So it is not surprising that attempts to develop mathematical models of cancer and therapies have typically been dismissed. Cancer, it would appear to some, is too complicated to model. More

Overcoming stem cell rejection by immune system
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Biologists at UC San Diego have discovered an effective strategy that could prevent the human immune system from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies. Their discovery may also provide scientists with a better understanding of how tumors evade the human immune system when they spread throughout the body. More


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Technological advances aid efforts to document human population diversity, history
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As we shuttle between airports or set off on New Year's cruises to the tropics, it's easy to take long-distance travel for granted, to dismiss the long, arduous journeys our ancient predecessors made across and between continents. But those migrations did more than disperse humans across the planet. They also helped shape subtle between-population differences and diversity in the human genome, as new locales presented distinct collections of environmental conditions, pathogens, and sometimes even other populations to mingle with. More

Global shift in R&D
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A new analysis of global biomedical research and development investments shows that the US is losing some of its dominance, as industry science funding in the US, in particular, has lagged just as countries in Asia and Oceania have been spending more on R&D. The analysis of global R&D trends between 2007 and 2012, published in the New England Journal of Medicine, found that the U.S. share of global biomedical research spending declined over the last five years from 51 percent to below 45 percent. More

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Graphene oxide halts bacterial growth on water-purifying membranes
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Turning seawater or sewage into drinkable water depends on the filtering power of thin polyamide membranes. Microbes glom onto and muck up these membranes, disrupting their ability to remove salts and contaminants. But attaching graphene oxide nanosheets to the polyamide materials reduces bacterial growth, according to a new study. These functionalized membranes may require less cleaning and last longer than those in use today. More

Scientists solve a sticky problem
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Scientists have uncovered how an ulcer causing stomach bacteria, that has been linked to gastric cancer, sticks to and infects the lining of the stomach and gut. Australian scientists have long had an interest in how the bacterium, Helicobacter pylori, causes ulcers and more rarely gastric cancer. Now, researchers have determined the 3-dimensional structure of a protein called SabA. More



New advances in the hydrophilicity of carotenoids
By Dr. Afsaneh Motamed-Khorasani    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Carotenoids have antioxidant properties and are mostly hydrophobic in nature. In recent years, attempts have been made to increase the hydrophilicity of carotenoids for their utilization as antioxidants in the medicine industry and colorants in food industry. Hydrophilic carotenoids are effective antioxidants and also possess new properties in comparison with parent compounds. Only a few hydrophilic compounds are available in nature, and chemical derivatization of the carotenoids has been recently attempted to improve the hydrophilicity of these compounds. More

Simple, cheap way to increase solar cell efficiency
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Researchers from North Carolina State University and the Chinese Academy of Sciences have found an easy way to modify the molecular structure of a polymer commonly used in solar cells. Their modification can increase solar cell efficiency by more than 30 percent. Polymer-based solar cells have two domains, consisting of an electron acceptor and an electron donor material. Excitons are the energy particles created by solar cells when light is absorbed. More

Delivering nucleic acids into cells
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Whether one is elucidating biological mechanisms, correcting a faulty gene, or modulating gene expression, artificially introducing nucleic acids into cells requires an efficient and nontoxic delivery method. Transfection (placing nucleic acids into cells by nonviral methods) and transduction (utilizing viral vectors) are fundamental tools for getting the payload into the cell of interest. More


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Career


Biomass Preprocessing Research Engineer
Idaho National Laboratory
US – ID – Idaho Falls

Postdoc – Hippocampal Interneurons and Cajal-Retzius Cells
Northwestern University
US – IL – Evanston

Boston Molecular Biology Instrument Sales Specialist
Life Science Search Solutions, Inc.
US – MA – Boston

More jobs at SLAS Career Connections


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