This message contains images. If you don't see images, click here to view. Advertise in this news brief. Advertisement Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit January 13, 2016 SLAS.org    SLAS2016    Moving? New job? Let SLAS know.       Advertisement Advertisement Advertisement Advertisement Advertisement Advertisement   Advertisement Five Posters Advance in SLAS2016 Student Poster Competition SLAS    Share    Congratulations to the five scientists whose work moves forward in the quest to earn a $500 cash award as winners of the annual Student Poster Competition: Jungho Ahn, Seoul National University Reconstituting three dimensional tumor microenvironment in vitro on a microfluidic chip (Poster #2019) John Bassett, The University of QLD Australia Development of an MDA-MB-231 breast cancer cell line expressing a GCaMP6 genetically encoded calcium sensor for high content imaging-based assessment of calcium signaling: novel opportunities for high throughput screening (Poster #4001) Joohung Kang, Wyss Institute/Harvard University Rapid enumeration and identification of rare food contaminant using a magnetic microfluidic device and FcMBL-conjugated magnetic particles (Poster #7015) Carrie Lovitt, Griffith University Australia Automated evaluation of anti-cancer activity in advanced tumor models (Poster #2003) Matsurah Bte Mohd Abdul Rashid, National University of Singapore Synergistic Combinations Against Bortezomib-Resistant Multiple Myeloma Derived via Phenotypic Personalized Medicine (PPM) (Poster #5005) Posters can be viewed Monday and Tuesday during Exhibition hours. Students are present for discussion from 1:00-3:00 p.m. Monday, Jan. 25. More Advertisement JBS Free Access: New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories SLAS    Share    NEW and FREE at JBS Online — this Montana Molecular/Scintillon Institute paper reports the development of two live-cell assays that are robust (Z′ > 0.7) and easily deployed on standard fluorescence plate readers. Discussion details the parameters that were critical for optimization in the hopes that the lessons learned can be generalized to the development of new biosensor-based assays. This is a SAGE Choice article, allowing all readers immediate free access to the full manuscript. More Advertisement View 50+ peer reviewed videos for 3D cell culture See how to grow and analyze spheroids in one microplate Get better accuracy and reproducibility from your automation tips Learn how to improve image capture and data quality during HCS Download a comprehensive selection guide for laboratory automation products There is Still Time to Pre-Register for SLAS2016 SLAS    Share    Save time in San Diego by pre-registering online today! Less time in the registration area means more time to: Attend podium presentations (136) featuring breakthrough research Explore 315 companies in the 62,500 sq. ft. Exhibition Take advantage of free career services Participate in an Exhibitor Tutorial or Special Interest Group session Make your way to the SLAS2016 Corner Bars for continued networking! Need help making the boss understand why you should attend SLAS2016, Jan. 23-27, San Diego? SLAS shows you how to make your business case. More Advertisement ROBOTIC SAMPLE HANDLING SYSTEMS Experience accelerated research and increased throughput with robotic sample loading systems and accessories from Prior Scientific. Select from our automated slide and well plate loaders, LED and metal halide fluorescence illuminators, Piezo Z stages, motorized filter wheels, high speed shutters as well as custom and OEM electromechanical and optical systems. Visit us at SLAS 2016 Booth#1256 SLAS ELN Reports: Melissa Crisp — A Guide to the Science and Technology Career Trail SLAS    Share    Melissa Crisp doesn't hesitate when it comes to surveying new frontiers on the career trail. She organized and networked her way through her academic career and early job searches and now guides others along their paths to success. "Most people want to know how to get a job," says Crisp, a research scientist in automation at Eli Lilly and Company's research and development site in San Diego, CA, and a member of the SLAS Student and Early Career Professionals Advisory Committee. "You're not going to know how to find a job the right way, network properly or how to position yourself in your career without some help." Read more in the SLAS Electronic Laboratory Neighborhood e-zine. More Advertisement Plan Your SLAS2016 Schedule Using these Handy Tools SLAS    Share    Browse the schedule of events or search by topic, title, track and more as you build your personalized schedule from a bustling SLAS2016 lineup of activities. The SLAS2016 Event Scheduler synchs with the SLAS2016 Conference App, available this week for Apple, Android and Kindle devices, to offer an easy way to navigate SLAS2016, Jan. 23-27, San Diego. Scan the QR code at right to download app for your device. More Advertisement Important factors to Consider for Thermal Shift Assays Download the Overcoming Technical Challenges in Cell-Based High Throughput Screens Whitepaper A Rising Tide Lifts All Shipshape Boats SLAS    Share    SLAS2016 keynote speaker Michael Gottesman discusses the omnibus budget bill signed by President Obama on Dec. 18, 2015, which included a $2 billion increase for the NIH. "This largest increase in the NIH budget in 12 years signals bipartisan support for the overall biomedical-research effort and a growing trust in NIH leadership and NIH-supported scientists to manage these funds effectively and efficiently," says NIH Deputy Director Gottesman in The NIH Catalyst. Gottesman's SLAS2016 address is Monday morning, Jan. 25. More Advertisement It's All About Your Data CLICK to see why CDD Vault is the Drug Discovery Informatics platform your Project Team will embrace, allowing you to effortlessly store & mine all data. Advertisement Become a Lab Superhero! The Mantis will revolutionize your workflow for applications including NGS sample prep, qPCR, assay development, and cellular assays. Automation made simple. Job Seekers and Employers Connect via SLAS Career Connections SLAS     Share    With SLAS2016 just around the corner, this online, targeted SLAS employment exchange is featuring a host of new job listings. Job seekers can post resumes and browse job openings for free. Employers can find prospective employees by reviewing posted resumes for free and attract interested applicants by posting job openings for a fee (SLAS Corporate Members receive a 50% discount). Attending SLAS2016? Take advantage of the expanded Career Connections services available in the SLAS Member Center at SLAS2016. More Advertisement AUTOMATED, REPRODUCIBLE PHOSPHOPEPTIDE ENRICHMENT New App Note! Agilent AssayMAP Sample Prep Platform Enables Reproducible Automated Phosphopeptide Enrichment. Advertisement Welcome to RAD Source Since 1997 Rad Source Technologies has been the expert in providing renewable, non-isotope, ionizing radiation replacements for self-shielded gamma irradiators. Currently, there are over 300 renowned hospital, university, and pharmaceutical research institutions using Rad Source X-ray technology. To find out more about our equipment, select your application and you will find equipment specifications, literature references, white papers, training videos, discussion forums, as well as other helpful info. Advertisement BumbleBee/Hive™ Automation Platform The BioNex Advantage: The unique vertical design of the Hive Automation Platform uses less of your precious laboratory space. To maximize speed, throughput and efficiency, the BumbleBee/Hive uses the entire above-deck and below deck spaces whereby plates, tubes and consumables can be continuously loaded and unloaded during runs during pipetting, eliminating traditional deck resetting time. Stir No More: Scientists Show That Draining Speeds Up Bioassays Lab Manager    Share    For many research scientists, idle time has long been an unwelcome feature of the discovery process. Advances in cellular biology have yielded popular and powerful tools to detect cellular proteins and DNA — largely by exploiting the unique and intricate interactions between these microscopic molecules. Scientists use these tools to advance research and diagnose diseases. But these come at a cost in time — from hours to days — before they yield accurate answers. More Advertisement New Method Allows Gene Expression Tracking over Generations of Cells Genetic Engineering and Biotechnology News    Share    MIT researchers engineered a microfluidic device that traces detailed family histories for several generations of cells descended from one "ancestor." Scientists at MIT said they can now trace detailed family histories for several generations of cells descended from one ancestor after combining RNA sequencing with a novel device that isolates single cells and their progeny. More Advertisement Synthetic Genomic Solutions SGI-DNA provides a variety of synthetic genomic solutions to advance your research. Our comprehensive suite of genomic services will allow you to discover, design, and build the sequences you need. Learn More Advertisement Tube Feeding, Labeling, and Racking Modular automation for tube and vial feeding, labeling, and racking including 600 dpi printer resolution, 'whisper' feed automatic feeders, and robotic racking systems. MORE Happy Accident Leads to Faster Synthesis Chemical & Engineering News    Share    When a power outage hit the labs of biochemist Tilman M. Hackeng of the University of Maastricht, his colleague Stijn M. Agten rushed to remove some samples from their ultra-performance liquid chromatography-tandem mass spectrometry machine. Agten was monitoring the progress of an oxime ligation reaction, and to give himself time to reboot the machine, he froze his samples to minus-20 degrees Celsius, expecting to slow the reaction rates and allow him to salvage something from his efforts. More Orthogonal Recognition Processes Drive the Assembly and Replication of a [2]Rotaxane Journal of the American Chemical Society    Share    Within a small, interconnected reaction network, orthogonal recognition processes drive the assembly and replication of a [2]rotaxane. Rotaxane formation is governed by a central, hydrogen-bonding-mediated binding equilibrium between a macrocycle and a linear component, which associate to give a reactive pseudorotaxane. Both the pseudorotaxane and the linear component undergo irreversible, recognition-mediated 1,3-dipolar cycloaddition reactions with a stoppering maleimide group, forming rotaxane and thread, respectively. More Advertisement KMC Systems Engineering & Manufacturing KMC Systems provides contract engineering and manufacturing services to leading and emerging OEMs. As a trusted outsourcing partner for 35 years, KMC Systems develops, designs and manufactures cutting-edge, full-system instrumentation for the medical and life science markets. Visit us online and download our brochure to learn more about KMC Systems. Advertisement The Concept Is Simple We work with scientists to design and develop new, innovative tools for biological, chemical, and materials research, both in basic studies and pharmaceutical and industrial applications. We know research, we know assay development, and we know tools development. Learn More Advertisement MaxCyte® VLX™ Large Scale Transfection System The MaxCyte® VLX™ Large Scale Transfection System is specifically designed for extremely large volume transfection and is able to transfect up to 2E11 cells in less than 30 minutes with high cell viability and transfection efficiencies. This system is ideal for rapid, gram scale production of proteins and monoclonal antibodies. Two-in-One Packaging May Increase Drug Efficacy and Reduce Side Effects Phys.org    Share    Chemotherapy often comes with powerful side effects, and one of the reasons for this is that the drugs used to kill cancer cells can also damage other fast-growing cells in the body, like hair follicles. But one possibility for reducing these side effects may be if the chemotherapy drugs only become toxic when they reach the tumor. The search for such targeted drug delivery options for chemotherapy and other treatments inspired a team of researchers to develop a new way to package two or more ingredients into a single capsule. More Cas9 Further Refined The Scientist    Share    Cas9 has several binding steps to help it home in on the right section of DNA when it's assigned a gene to edit, but no system is perfect — the nuclease still occasionally binds to the wrong stretch of nucleotides. In an effort to eliminate these mistakes, researchers from Harvard University and Massachusetts General Hospital have engineered a Cas9 mutant with a reduced ability to bind to the DNA's phosphate backbone. More Advertisement A 'Printing Press' for Nanoparticles Science Daily    Share    Gold nanoparticles have unusual properties, which scientists are seeking to put to use in a range of technologies. Some of the most interesting properties emerge when nanoparticles are brought close together. But a major challenge has been finding ways to assemble these bits of gold while controlling the three-dimensional shape of their arrangement. In a new article, researchers outline a new technique. More Scientist Identifies Energy Sensor as Potential Target for Cancer Drugs Bioscience Technology    Share    An international research team formed by a University of Cincinnati cancer researcher has shown for the first time that a specific enzyme is responsible for sensing the available supply of GTP, an energy source that fuels the uncontrolled growth of cancer cells. The research underscores the enzyme's potential to become a therapeutic target for future cancer drugs. More Advertisement Sr. R&D Manager – Mechanical Engineering Labcyte Inc. US – CA – Sunnyvale Scientist I/II ImmunoGen US – MA – Waltham Rosetta Commons REU Intership Johns Hopkins University Institute for Nanobiotechnology US – MD – Baltimore Search Jobs at SLAS Career Connections   SLAS Point-to-Point Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit Dennis Hall, Executive Editor, 469.420.2656    Contribute news This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free! SLAS Terms of Use Policy Recent issues Jan. 6, 2016 Dec. 28, 2015 Dec. 23, 2015 Dec. 16, 2015 7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063