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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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Speed, sensitivity and precision in all detection modes. BMG LABTECH’s PHERAstar FS has no equal.
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SLAS returns to San Diego in 2014
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As SLAS2013 comes to a close today in Orlando, Fla., plans are already well underway for SLAS2014, Jan. 18-22, at the San Diego Convention Center, San Diego, Calif. SLAS2014 co-chairs are Michele Cleary, Ph.D., of Merck in West Point, Pa., and David Eddington, Ph.D., of University of Illinois at Chicago, Chicago, Ill. Mark your calendar now.
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SLAS announces plan for expansion in Europe
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At SLAS2013, incoming SLAS Board President Jeff Paslay announced the Society's formal business plan to grow and re-engage constituents in Europe at a higher level. According to Paslay, the plan will officially commence later in 2013. SLAS will take a deliberate approach and start with grassroots activities to build brand awareness and strengthen member engagement, gradually moving towards more substantial activities and events. While subject to change, Paslay cited Denmark, Germany, Spain, Switzerland and the United Kingdom as the initial target markets for SLAS. "Laboratory science and technology are crucial to many European-based organizations and industries. We feel that the expert resources, education and peer-to-peer intelligent networking that SLAS can provide will be of tremendous and immediate value to laboratory professionals, researchers, technologists and academics in Europe," said Paslay.
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Three-time SLAS Tony B. Academic Travel Award recipient featured
in SLAS ELN e-zine
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Krishna Vattipalli talks about the impact the SLAS community and mentors have had on his career growth. He also discusses his SLAS2013 podium presentation, "Performance Comparison of Nanomonitor against Elisa on Patient Pool Samples," and details his work in the early diagnosis of cardiac markers to enhance patient outcomes. He describes how his laboratory uses an electrochemical-based nanomonitor that requires mere drops of blood to test for Troponin-T, a representative biomarker sometimes present in cardiac events or stroke. Read more in SLAS Electronic Laboratory Neighborhood e-zine.
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JALA and JBS manuscript proposal deadlines near
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The SLAS journal publishing team is working on three special issues with first quarter 2013 deadlines:
January 25: JBS Special Issue on Phenotypic Drug Discovery
Guest editors: Ellen L. Berg, Ph.D., and Jonathan A. Lee, Ph.D.
January 25: JALA Advancements in Biomedical Micro/Nano Tools and Technology
Co-Guest editors: Eric Pei-Yu Chiou, Ph.D., of University of California, Los Angeles and Hideaki Tsutsui, Ph.D., of University of California, Riverside
March 15: JALA New Developments in Global Health Technologies
Guest editor: Peter B. Lillehoj, Ph.D., of Michigan State University
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For more information visit www.parker.com/precisionfluidics or email ppfinfo@parker.com.
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Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption.
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This application note by INTEGRA discusses and demonstrates how the advent of adjustable spacing multichannel pipettes presents labs with a valuable new tool for accelerating tasks where samples need reformatting while at the same time increasing precision, reliability and comfort of the pipetting procedure. MORE
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At Molecular Devices, we understand your desire for a top-of-the-line multi-mode microplate reader while balancing an ever-tightening budget. Get the reliability and sensitivity your lab deserves at the price-point you need from a name you trust. Learn more at info.moleculardevices.com
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SLAS Journal Achievement Award honorees announced at SLAS2013
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Readers' Choice, Authors' Choice and Reviewer Excellence Awards acknowledge the year-round impact of the two SLAS internationally recognized peer-reviewed scientific journals, the Journal of Laboratory Automation and the Journal of Biomolecular Screening. Review the list of winners and access their papers at SLAS.org.
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Become an SLAS volunteer!
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SLAS believes the more energy and effort you invest in your membership, the greater benefits you receive in return. As a volunteer, you can expand your personal and professional network working with other talented professionals, while contributing to the future of laboratory science and technology. Complete a short form to let SLAS know your interests.
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 SLAS Facebook photo wrap-up of SLAS2013
SLAS Share
Experience the excitement of SLAS2013 while viewing pictures from the event held Jan. 12-16 at the Gaylord Palms Convention Center in Orlando, Fla.
Enjoy!
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Increasing science strategic planning success
Genetic Engineering & Biotechnology News Share
Why should science organizations do strategic planning? Conventional businesses often struggle with it, and their products and services are much easier to understand and predict than the compounds in development in a lab. Science organizations understandably overlook strategic planning because their focus on their science absorbs the lion's share of their interest.
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O2-independent formation of the inactive states of NiFe hydrogenase
Nature Chemical Biology Share
We studied the mechanism of aerobic inactivation of Desulfovibrio fructosovorans nickel-iron (NiFe) hydrogenase by quantitatively examining the results of electrochemistry, EPR and FTIR experiments. They suggest that, contrary to the commonly accepted mechanism, the attacking O2 is not incorporated as an active site ligand but, rather, acts as an electron acceptor. Our findings offer new ways toward the understanding of O2 inactivation and O2 tolerance in NiFe hydrogenases.
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Astronomers find massive supply of gas around modern galaxies
ScienceDaily Share
Galaxies have a voracious appetite for fuel — in this case, fresh gas — but astronomers have had difficulty finding the pristine gas that should be falling onto galaxies. Now, scientists have provided direct empirical evidence for these gas flows using new observations from the Hubble Space Telescope.
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Newfound brain cells linked to high blood pressure
LiveScience Share
High blood pressure has just gotten a new culprit: a newly discovered brain cell. While the usual suspects of heart risk — weight problems, stress, smoking, those salty slices of bacon — do contribute to high blood pressure, researchers think they've discovered a new cluster of neurons that also play a role.
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How to treat heat like light
Lab Manager Share
A Massachusetts Institute of Technology researcher has developed a technique that provides a new way of manipulating heat, allowing it to be controlled much as light waves can be manipulated by lenses and mirrors.
The approach relies on engineered materials consisting of nanostructured semiconductor alloy crystals.
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The secrets of a tadpole's tail and the implications for human healing
Bioscience Technology Share
Scientists at The University of Manchester have made a surprising finding after studying how tadpoles re-grow their tails which could have big implications for research into human healing and regeneration. It is generally appreciated that frogs and salamanders have remarkable regenerative capacities, in contrast to mammals, including humans.
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Iterative refinement of a binding pocket model: Active computational steering of lead optimization
Journal of Medicinal Chemistry Share
Computational approaches for binding affinity prediction are most frequently demonstrated through cross-validation within a series of molecules or through performance shown on a blinded test set. Here, we show how such a system performs in an iterative, temporal lead optimization exercise. A series of gyrase inhibitors with known synthetic order formed the set of molecules that could be selected for "synthesis."
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Positively scintillating neutral particles brighten scientific prospects
Science & Technology Review Share
Since the 1930s, when Austrian-born physicist Wolfgang Pauli first theorized the existence of the neutrino, this tiny, nearly massless particle with no charge has made mighty contributions to scientific exploration. Researchers first thought the neutrino would be undetectable because it seldom interacts with matter and is not affected by the electromagnetic force. But its existence was proven 25 years later.
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Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.
Discover Picus at www.sartorius.com/picus.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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Dennis Hall, Senior Content Editor, 469.420.2656
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Johns Hopkins scientists win JALA & JBS Art of Science Contest
