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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Jan. 22, 2014

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SLAS2014: Great science, great people
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The SLAS Third Annual Conference and Exhibition comes to a close today at the San Diego Convention Center in San Diego. Watch Twitter for the announcement of the 2014 SLAS Innovation Award winner today (about 5 p.m. PT), see more photos on Facebook and catch up on some of the discussions building on SLAS LinkedIn and the SLAS Special Interest Group LinkedIn subgroups. More



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SLAS ELN Reports: New SLAS Board Members Value Collaboration and Community
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Building, nurturing and accessing a robust network of scientific colleagues is vital to success in an increasingly global market according to Alastair Binnie, Bristol-Myers Squibb; Richard M. Eglen, Corning Life Sciences; and Michael (Mike) Snowden, AstraZeneca. Each has benefitted from powerful professional communities and now they're driven to give back by stepping into SLAS executive leadership roles. Get to know these leaders in the SLAS Electronic Laboratory Neighborhood e-zine. More

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New at JALA Online: Special issue on Advancements in Biomedical Micro/Nano Tools and Technology
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Part two of this special issue by guest editors Eric Pei-Yu Chiou and Hideaki Tsutsui includes review articles, "Physical Methods for Intracellular Delivery: Practical Aspects from Laboratory Use to Industrial-Scale Processing" and "Modeling Mass Transfer from Carmustine-Loaded Polymeric Implants for Malignant Gliomas."
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JALA & JBS Art of Science Contest voting ends Jan. 31
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The race to the finish accelerated through voting at the SLAS2014 Member Center in San Diego, but there still is time to cast your vote for the coolest image in the contest. Help one scientist/artist win a $500 Amazon gift card! More


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SLAS Webinar Series: Protein-Protein Interactions as Small Molecule Drug Targets
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SLAS delivers world-class education and information to your desktop again this spring. Register today for:
March 18: Challenging Targets for Drug Discovery
April 15: Targeting Protein-Protein Interactions as an Anticancer Strategy
May 13: Cellular Protein: Protein Interaction Assays Implemented using BacMam
Webinars are FREE to dues-paid SLAS members.
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'How to' video: Set up for a world-class exhibition
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Take a tour of the SLAS2014 Exhibit Hall with Barry Sacks, SLAS exhibits manager, one full day before it opened to those seeking to explore new products and services of more than 300 multinational companies. Instead of impressive equipment and colorful displays, you’ll see busy forklifts, mountains of crates and hard-working set-up teams! More

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Efficient syntheses of korupensamines A, B and michellamine B by asymmetric Suzuki-Miyaura coupling reactions
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Efficient asymmetric Suzuki-Miyaura coupling reactions are employed for the first time in total syntheses of chiral biaryl natural products korupensamine A and B in combination with an effective diastereoselective hydrogenation, allowing ultimately a concise and stereoselective synthesis of michellamine B. Chiral monophosphorus ligands L1–3 are effective for the syntheses of a series of functionalized chiral biaryls by asymmetric Suzuki-Miyaura coupling reactions in excellent yields and enantioselectivities (up to 99% ee). More

Grants available for microRNA, long non-coding RNA or mRNA research
Exiqon    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Three grants of $12,500 (€9000) each in free Exiqon products or services will be awarded to groundbreaking research projects in the fields of microRNA, long non-coding RNA or mRNA. Online applications will be accepted through Jan. 31, 2014. The Exiqon Grant Program is open to researchers at academic institutions and non-profit research centers across the world. More

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Under controversial patent regime, Indian companies supply pharmaceuticals to patients globally
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In October 2013, at the pharmaceutical trade show CPhI in Frankfurt, Germany, officials from India announced a goal of raising that country's drug exports from $15 billion per year currently to $25 billion by 2016. The goal is part of a larger campaign launched in 2012 to position India as the "pharmacy to the world." Considering the recent headlines about India's drug industry, the campaign's goal seems optimistic. More

Discovery could offer new way to treat prion diseases
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
New research from the University of Alberta has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years. The new findings "present a breakthrough in understanding the secret life of prion molecules in the brain and may offer a new way to treat prion diseases," said project leader David Westaway. More


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Plastic injection protects mouse hearts after attack
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The discovery was a happy accident. It turns out that an injection of microscopic tags made of a plastic-like polymer can help limit tissue damage after a heart attack in mice. The hope is that it could one day help treat this and other conditions in humans. The hunt to find a therapy that shuts down inflammatory monocytes — a kind of immune cell that can damage the body after a heart attack and in other illnesses — has been long and elusive, says Stephen Miller at Northwestern University. More

Progress in stem cell pluripotency
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The stem cell world finds itself at a critical juncture as the new year begins. That's the view of Paul Knoepfler, Ph.D., associate professor at the UC Davis School of Medicine. Last month he moderated one of the sessions at the Genetics Policy Institute's "World Stem Cell Summit." "The field has been buoyed by building momentum for both transformative basic science discoveries and clinical translation of stem cells," he noted. More

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Live cell chemical profiling of temporal redox dynamics in a photoautotrophic cyanobacterium
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Protein reduction–oxidation modification is an important mechanism that allows microorganisms to sense environmental changes and initiate cellular responses. We have developed a quantitative chemical probe approach for live cell labeling and imaging of proteins that are sensitive to redox modifications. More

Researchers harness sun's energy during day for use at night
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Solar energy has long been used as a clean alternative to fossil fuels such as coal and oil, but it could only be harnessed during the day when the sun's rays were strongest. Now researchers led by Tom Meyer at the Energy Frontier Research Center at the University of North Carolina at Chapel Hill have built a system that converts the sun's energy not into electricity but hydrogen fuel and stores it for later use, allowing us to power our devices long after the sun goes down. More



Genome of the blood-sucking hookworm decoded
Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have decoded the genome of a lowly, blood-sucking hookworm, an advance they say could lead to cures for hookworm infection, a painful condition afflicting more than 700 million people worldwide, mostly in underdeveloped countries. But the worm's unique relationship with the human immune system means the new findings may also provide insights into treating autoimmune diseases rampant in the United States. More

Immune cells may heal an injured heart
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The immune system plays an important role in the heart's response to injury. But until recently, confusing data made it difficult to distinguish the immune factors that encourage the heart to heal following a heart attack, for example, from those that lead to further damage. Now, researchers at Washington University School of Medicine in St. Louis have shown that two major pools of immune cells are at work in the heart. More


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    Senior Research Scientist – High-Throughput Screening
    Vertex Pharmaceuticals, Inc.
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    Applications Scientist
    Fluid Imaging Technologies
    US – CA

    More jobs at SLAS Career Connections


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