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Start 2020 off right with an SLAS Premier Membership. Join today for 12 months of connections, exclusive scientific content, event discounts and much more.
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February's SLAS Discovery Special Issue, 'Advances in Cellular Target Engagement and Target Deconvolution' Now Available
SLAS
The February special issue of SLAS Discovery, "Advances in Cellular Target Engagement and Target Deconvolution," features 13 articles focused on multiple aspects of and technologies related to cellular target engagement. Special issue editors Martin Main, Ph.D., (Medicines Discovery Catapult, UK) and Andrew Zhang, Ph.D., (AstraZeneca, USA) selected articles that span a variety of relevant topics, from the direct measurement of compound-target interaction using BRET technologies to the measurement of compound-induced changes in protein stability and localization. Open access is available until February 20.
READ MORE IN SLAS DISCOVERY
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Access is Now Available for February's SLAS Technology Special Issue, 'Flexible Analytical Devices for Point-of-Care Testing'
SLAS
The first SLAS Technology issue of 2020, "Flexible Analytical Devices for Point-of-Care Testing," features a series of articles and research reviews highlighting the ever-increasing popularity of wearable technology devices as they apply to disease detection and health monitoring. Special issue Editors Hideaki Tsutsui, Ph.D., (University of California Riverside, USA) and Peter Lillehoj, Ph.D., (Michigan State University, USA) selected eight articles focused on recent technological advances, challenges and the future direction of these devices as they apply to medicine. Now available through February 20.
ACCESS FEBRUARY’S SLAS TECHNOLOGY
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European Sample Management Symposium Keynote Speaker Announced
SLAS
Gisbert Schneider, Ph.D., professor and Chair for Computer-Assisted Drug Design at ETH Zurich, is a pioneer in the integration of machine-learning methods into practical medicinal chemistry. He coined the phrases "scaffold-hopping" and "frequent hitter" and his research has led him to hold many top positions in both academia and pharma. He is also confirmed as this year's European Sample Management Symposium keynote speaker (16-17 March, Berlin, Germany) where he'll present on molecules on demand and the opportunities and limitations of designing them using machine intelligence. This is a can't-miss presentation that we're very excited to host!
As a reminder, the deadline to submit a poster abstract related to supply chain management, sample collections, data management or robotics AND the opportunity to save with the Early Bird Registration rate is Monday, 10 February.
VIEW COMPLETE SYMPOSIUM DETAILS
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SLAS Europe 2020 Conference and Exhibition Important Deadline Reminder
SLAS
Several important SLAS Europe 2020 abstract deadlines are closing within the next six weeks. This year, research is being accepted in scientific tracks of emerging biology, technology, discovery and careers in business and technology. Are you prepared? This will be the first year that up to three students will be chosen for a Student Poster Award at an SLAS Europe conference. Share this opportunity with your academic colleagues.
- Podium Submission Deadline: Monday, 3 February
- Tony B. Academic Travel Award Application Deadline Podium): Monday, 3 February
- Tony B. Academic Travel Award Application Deadline (Poster Only): Monday, 2 March
- Innovation AveNEW Exhibition Applications Deadline: Monday, 2 March
Plus, registration will open soon for this year’s conference in Vienna, Austria, 2-5 June. Save the date!
VIEW SLAS EUROPE 2020 DETAILS
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SLAS2020 is Next Week!
SLAS
Don't forget these important reminders that will help level up and make the most out of your time in San Diego:
Download the SLAS2020 Conference App to access:
- direct access to the SLAS Ignite Partnership Tool
- the most up-to-date conference schedule, abstracts and exhibitor directory
- exclusive access to session speaker Q&A
- conference-related maps, including the conference center and Exhibition
- automatic program updates and notifications
- access to the e-poster gallery
To access, search "SLAS Events" in your favorite app store or visit the SLAS2020 Conference App page for complete details.
VIEW COMPLETE CONFERENCE APP DETAILS
While in the Conference App, Create Your SLAS Ignite Partnership Profile
The SLAS Ignite Partnership Tool was created to foster future collaboration opportunities between SLAS2020 attendees. Search and connect with your colleagues based on similar interests and set up a time to meet and discuss future partnership possibilities. One-touch access is available through the SLAS2020 Conference App or at the link below.
ACCESS THE SLAS IGNITE PARTNERSHIP TOOL
SLAS2020 Rates Increase January 25
Online registration will remain open during the conference, but the current registration rate will increase this Saturday, January 25. Reserve your spot today or tomorrow and save $200!
REGISTER NOW
Get CONNECTED: Introduce Yourself to Fellow SLAS2020 Attendees
Before landing in San Diego, log on to CONNECTED and introduce yourself to other SLAS2020 registrants. As a registered attendee, you have access to this exclusive online community designed to as a place to connect and share all things SLAS2020. To connect:
GET CONNECTED
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Black Dog offers quality refurbished FLIPR® fluorescence readers and FLIPRTETRA® cellular screening systems at affordable prices. Take advantage of Black Dog's 15-Year Anniversary Promotion: SAVE 15% on your instrument purchase and get a 15-Month Warranty*! Cost-effective leasing options are also available. Hurry, offer ends March 31, 2020.
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Calendar of Important Dates
SLAS
Journal Deadlines
Hit Discovery Methodology
Proposals due January 31
AI in Process Automation
Proposals due: On a rolling basis
Early Drug Discovery Approaches with More Physiologically Relevant Targets
Proposals due March 31
Advances in Protein Degradation
Proposals due March 31
Upcoming Events
Come see SLAS at these important events:
SLAS2020 International Conference and Exhibition
January 25 – 29, 2020
San Diego, CA, USA
View SLAS2020 Sponsorship Opportunities
SLAS 2020 European Sample Management Symposium — Registration Now Open!
Berlin, Germany
16-17 March 2020
Poster Submission Deadline: Monday, 10 February
SLAS 2020 Europe Conference and Exhibition — Now Accepting Podium and Poster Abstracts!
Vienna, Austria
2-5 June 2020
Podium Submission Deadline: Monday, 3 February
Tony B. Application Deadline (Podium): Monday, 3 February
Tony B. Application Deadline (Poster Only): Monday, 2 March
Innovation AveNew Application Deadline: Monday, 2 March
Student Poster Submission Deadline: Monday, 6 April
Final Poster Submission Deadline: Monday, 27 April
COMPLETE LIST OF SLAS CONFERENCES AND SYMPOSIA
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SPONSORED VIDEO |
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Promoted by
Thermo Scientific
The Thermo Scientific™ inSPIRE™ collaborative system brings interactive, configurable solutions to the lab to automate your research. Learn how our unique touch-enabled technology and modular design is delivering inSPIREd science.
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Multivalent Cation-Induced Actuation of DNA-Mediated Colloidal Superlattices
Journal of the American Chemical Society
Nanoparticles functionalized with DNA can assemble into ordered superlattices with defined crystal habits through programmable DNA "bonds." Here, we examine the interactions of multivalent cations with these DNA bonds as a chemical approach for actuating colloidal superlattices. Multivalent cations alter DNA structure on the molecular scale, enabling the DNA "bond length" to be reversibly altered between 17 and 3 nm, ultimately leading to changes in the overall dimensions of the micrometer-sized superlattice.
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Predicting Breast Cancer by Paper Spray Ion Mobility Spectrometry Mass Spectrometry and Machine Learning
Analytical Chemistry
Paper spray ionization has been used as a fast sampling/ionization method for the direct mass spectrometric analysis of biological samples at ambient conditions. Here, we demonstrated that by utilizing paper spray ionization-mass spectrometry coupled with field asymmetric waveform ion mobility spectrometry, predictive metabolic and lipidomic profiles of routine breast core needle biopsies could be obtained effectively.
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Chemists Teach Neural Networks to Predict Properties of Compounds
Phys.org
A new joint Russian-French-Japanese team has developed a computational model able to predict the properties of new molecules based on the analysis of fundamental chemical laws. The study, titled "Using AI methods for the planning of chemical synthesis," is published in the Journal of Chemical Information and Modeling.
Associate Professor Timur Madzhidov says, "We offered a way to insert the preexisting chemical equations into some frameworks of machine learning."
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Walking With Atoms: Chemical Bond Making and Breaking Recorded in Action
Science Daily
Ever since it was proposed that atoms are building blocks of the world, scientists have been trying to understand how and why they bond to each other. Be it a molecule (which is a group of atoms joined together in a particular fashion), or a block of material or a whole living organism, ultimately, everything is controlled by the way atoms bond, and the way bonds break.
The challenge is that lengths of chemical bonds are between 0.1-0.3 nm, about half a million times smaller than the width of a human hair, making direct imaging of bonding between a pair of atoms difficult.
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Opening up DNA to Delete Disease
Lab Manager
Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assaults on disease.
The DNA-binding editorial assistants were devised by a US-based team of bioengineers, who describe their design in APL Bioengineering, from AIP Publishing.
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Multimodal Genomic Predictor of Immunotherapy Success
Genetic Engineering & Biotechnology News
Immune checkpoint inhibitor drugs have added a dimension to physicians' arsenal in their fight against cancer. However, not all patients will respond to the currently approved therapies, wasting precious time that could be spent using other potentially lifesaving drugs. Successes are limited by the lack of biomarkers that identify patients most likely to respond. Now, a team of investigators have developed an integrated genomic approach that potentially could help physicians predict which patients with non-small cell lung cancer will respond to therapy with immune checkpoint inhibitors.
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New iPSC Culture Medium Promises Weekends Off at Low Costs
The Scientist
Stem cell biologists rarely get weekends off. Seven days a week, their labs need someone to change the media keeping induced pluripotent stem cells alive. For many groups that use iPSCs, weekend lab visits — and expensive culture media — are considered inescapable facts of research.
In an effort to solve both problems, researchers at Northwestern University's Feinberg School of Medicine have developed a new human iPSC culture medium any lab can make from scratch at low cost and while taking weekends off.
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EU Moves Toward Strict Controls on 3 Plastics Chemicals and PFBS
Chemical & Engineering News
The European Union is taking aim at two chemicals used in polymer production, a phthalate, and a perfluorinated compound and its salts. All are now on a list of substances that are candidates for strict regulation.
If the chemicals on the list are selected for further controls, companies would only be allowed to use them if the European Chemicals Agency authorizes specific uses. ECHA says it added three of the substances to the list on Jan. 16 because they are reproductive toxics.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
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NMSU Chemical & Materials Engineering
US – NM – Las Cruces
Research Specialist A
University of Pennsylvania
US – PA – Philadelphia
Research Technologist I
University of Nebraska Medical Center
US – NE – Omaha
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