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Interactive e-zine sharing experiences and perspectives on science-related topics.
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On-demand scientific presentations: two live streamed sessions from SLAS2013. Available 365/24/7.
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 Andrea Weston earns 2013 SLAS Innovation Award
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SLAS congratulates Andrea Weston, Bristol-Myers Squibb, for her 2013 SLAS Innovation Award-winning presentation, "Making a Quantum Leap in Mass Spectrometry Throughput: Applying the NextVal MassInsight Technology to Monitor Cytochrome P450 Enzyme Inhibition in Human Liver Microsomes."
Weston, one of nine finalists for the prestigious annual award, was judged best for quality of science, impact on laboratory automation and screening, originality and creativity.
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 JALA and JBS special issues proposal deadlines in two days
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Jan. 25 is the deadline to submit manuscript proposals for the JBS Special Issue on Phenotypic Drug Discovery and the JALA Special Issue on Advancements in Biomedical Micro/Nano Tools and Technology.
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Honarnejad, Jacobs and Wu earn top SLAS student poster honors
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Congratulations to Kamran Honarnejad, M.Sc., University of Munich (Development and Implementation of a High-throughput FRET-based Calcium Imaging Assay for Alzheimer's Disease Drug Screening); Michael T. Jacobs, The University of Texas at Dallas (A Novel Nanotexturing Approach for Enhanced Biomarker Detection); and Yang Wu, Ph.D., University of New Mexico, (Discovery of Regulators of Receptor Internalization by High Throughput Flow Cytometry).
Take a look at the SLAS2013 Poster Gallery.
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Three companies receive SLAS New Product Award designations
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More than 66 new products were launched at SLAS2013, and three companies were selected by a panel of judges to receive the SLAS New Product Award (NPA) designation, recognizing the best of what's new on the exhibit floor. NPA winners were Andrew Alliance for Andrew, GenCell Biosystems for GenCell GT-Series and Prior Scientific for LumaSpec800.
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San Diego and Washington, DC, named future sites for SLAS annual conferences
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Beginning with SLAS2014 in San Diego, SLAS will rotate its annual conference and exhibition between these highly accessible west and east coast locations. "After comprehensive consideration and negotiation with many different locations and venues, it was unanimously agreed by the SLAS Board of Directors that San Diego will become the stage for SLAS2014, SLAS2016 and SLAS2018; while Washington, D.C., will serve as home to SLAS2015, SLAS2017 and SLAS2019," said 2012 SLAS President Dave Dorsett at SLAS2013. "California and the northeastern states house strong populations of laboratory science and technology professionals working in academic, corporate and government environments."
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NEW! JALA February issue podcast is live
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February JALA author Na Li, Ph.D., talks with JALA Podcast Editor David Pechter about her featured manuscript, "Reversible Regulation of Aptamer Activity with Effector-Responsive Hairpin Oligonucleotides." Li is in the Department of Mechanical and Aerospace Engineering at the University of Miami, Coral Gables, Fla.
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Add your SLAS2013 photos to the SLAS Facebook page
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SLAS invites you to share your SLAS2013 photos on the SLAS Facebook page. Let others see what you experienced at the Jan. 12-16 event at the Gaylord Palms Convention Center in Orlando, FL.
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'Quadruple helix' DNA discovered in human cells
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In 1953, Cambridge researchers Watson and Crick published a paper describing the interweaving "double helix" DNA structure — the chemical code for all life. Now, in the year of that scientific landmark's 60th Anniversary, Cambridge researchers have published a paper proving that four-stranded "quadruple helix" DNA structures — known as G-quadruplexes — also exist within the human genome.
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NIH director: Medical research at risk with sequestration
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From his perch at the National Institutes of Health's sprawling campus in Bethesda, Md., Director Francis Collins is eyeing the impending sequestration cuts warily. If lawmakers don't find a way to blunt the across-the-board cuts, the government's premier medical research center will lose 6.4 percent of its budget — a cut Collins calls a "profound and devastating blow" for medical research at a time of unprecedented scientific discovery.
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In the search for new drugs, diverging roads for microdosing
Chemical & Engineering News Share
When microdosing was the next big thing — back in the early to mid-2000s — drug developers had great plans for it. One of the problems with drug development is that failures often happen late in the development process. Microdosing offered a way to identify potential failures earlier, before full-fledged clinical trials.
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Men commit more scientific fraud than women
LiveScience Share
Men are more likely than women to commit scientific fraud, a new analysis of misconduct convictions reveals. And the urge to cheat spans the entire range of academic careers, from students to seasoned professors. For the new study, published in the journal mBio, scientists examined 228 cases of misconduct in the records of the United States Office of Research Integrity.
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Turning back the evolutionary clock
Bioscience Technology Share
John Chaput and his research team are developing new exotic molecules called XNA, that are alternatives to natural DNA and RNA. The team is simultaneously working with these molecules in two very different directions. In one effort, they are determining whether XNA contributed to the rise of life on Earth. At the same time, the team also is evolving XNA molecules with functions that could be used to diagnose and treat human diseases.
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In vitro demonstration of apoptosis mediated photodynamic activity and NIR nucleus imaging through a novel porphyrin
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We synthesized a novel water-soluble porphyrin THPP and its metalated derivative Zn-THPP having excellent triplet excited state quantum yields and singlet oxygen generation efficiency. When compared to U.S. Food and Drug Administration approved and clinically used sensitizer Photofrin, THPP showed ca. 2–3-fold higher in vitro photodynamic activity in different cell lines under identical conditions.
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Twitter reveals how Higgs gossip reached fever pitch
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Anyone who fondly remembers the heady days in early July 2012 when the discovery of the Higgs boson was hotly anticipated, and eventually announced, can now relive the thrilling experience thanks to an analysis of Higgs-related traffic on Twitter. The traffic — amounting to more than 1 million tweets — provides a neat reflection of real-world excitement, starting with rumors and eventually erupting into a buzz of Higgsteria.
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Will the zebrafish transform medicine?
Popular Science Share
The animal facility on the bottom floor of a drab building at Duke University is uncomfortably warm and smells a bit like raw seafood. That's not surprising given what's down there. The space holds a few thousand plastic fish tanks, each home to dozens of zebrafish: one-inch-long, big-eyed vertebrates that are becoming go-to research subjects for many scientists.
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Big pharma's reputation sinks with patient groups
eBioNews Share
Big Pharma's reputation among patient groups tumbled in 2012 with only 34 percent of participants in an annual survey saying multinational firms had an excellent or good reputation, compared to 43 percent a year ago. The 2012 survey of the corporate reputation of pharma, biotech and the healthcare industry found the industry took a drubbing for a lack of fair pricing policies, lack of transparency in all corporate activities and poor management of adverse news about products.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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